MovDisordV3, PubMed, Corpus, bibRecord, 003153

Preserved myocardial [123I]metaiodobenzylguanidine uptake in autosomal recessive juvenile parkinsonism: first case report.

Identifieur interne : 003153 ( PubMed/Corpus ); précédent : 003152; suivant : 003154

Preserved myocardial [123I]metaiodobenzylguanidine uptake in autosomal recessive juvenile parkinsonism: first case report.

Auteurs : Masahiko Suzuki ; Nobutaka Hattori ; Satoshi Orimo ; Nobuyoshi Fukumitsu ; Masahiro Abo ; Yu Kono ; Renpei Sengoku ; Akira Kurita ; Hidehiko Honda ; Kiyoharu Inoue

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2005.

RBID : pubmed:15704207

English descriptors

KwdEn :
- 3-Iodobenzylguanidine (diagnostic use), 3-Iodobenzylguanidine (pharmacokinetics), Exons (genetics), Humans, Male, Middle Aged, Myocardium (metabolism), Parkinsonian Disorders (genetics), Parkinsonian Disorders (radionuclide imaging), Radionuclide Imaging, Radiopharmaceuticals (diagnostic use), Radiopharmaceuticals (pharmacokinetics).
MESH :
- chemical , diagnostic use : 3-Iodobenzylguanidine, Radiopharmaceuticals.
- chemical , pharmacokinetics : 3-Iodobenzylguanidine, Radiopharmaceuticals.
- genetics : Exons, Parkinsonian Disorders.
- metabolism : Myocardium.
- radionuclide imaging : Parkinsonian Disorders.
- Humans, Male, Middle Aged, Radionuclide Imaging.

Abstract

A decrease in myocardial uptake of iodine-123-labeled metaiodobenzylguanidine (123I-MIBG) has been reported in idiopathic Parkinson's disease (PD) using 123I-MIBG myocardial scintigraphy. However, the patient with autosomal recessive juvenile parkinsonism (AR-JP), caused by the parkin gene, presented here showed normal 123I-MIBG myocardial uptake, suggesting that AR-JP is a distinct disease entity from PD. Although the clinical features of AR-JP are sometimes quite similar to those of late-onset idiopathic PD, 123I-MIBG myocardial scintigraphy may be a powerful tool to differentiate PD from other parkinsonian syndromes, including AR-JP.

DOI: 10.1002/mds.20384
PubMed: 15704207

Links to Exploration step

pubmed:15704207

Le document en format XML

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<author><name sortKey="Suzuki, Masahiko" sort="Suzuki, Masahiko" uniqKey="Suzuki M" first="Masahiko" last="Suzuki">Masahiko Suzuki</name>
<affiliation><nlm:affiliation>Department of Neurology, The Jikei University School of Medicine, Tokyo, Japan. suzukimd@jikei.ac.jp</nlm:affiliation>
</affiliation>
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<author><name sortKey="Hattori, Nobutaka" sort="Hattori, Nobutaka" uniqKey="Hattori N" first="Nobutaka" last="Hattori">Nobutaka Hattori</name>
</author>
<author><name sortKey="Orimo, Satoshi" sort="Orimo, Satoshi" uniqKey="Orimo S" first="Satoshi" last="Orimo">Satoshi Orimo</name>
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<author><name sortKey="Fukumitsu, Nobuyoshi" sort="Fukumitsu, Nobuyoshi" uniqKey="Fukumitsu N" first="Nobuyoshi" last="Fukumitsu">Nobuyoshi Fukumitsu</name>
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<author><name sortKey="Abo, Masahiro" sort="Abo, Masahiro" uniqKey="Abo M" first="Masahiro" last="Abo">Masahiro Abo</name>
</author>
<author><name sortKey="Kono, Yu" sort="Kono, Yu" uniqKey="Kono Y" first="Yu" last="Kono">Yu Kono</name>
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<author><name sortKey="Sengoku, Renpei" sort="Sengoku, Renpei" uniqKey="Sengoku R" first="Renpei" last="Sengoku">Renpei Sengoku</name>
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<author><name sortKey="Kurita, Akira" sort="Kurita, Akira" uniqKey="Kurita A" first="Akira" last="Kurita">Akira Kurita</name>
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<author><name sortKey="Honda, Hidehiko" sort="Honda, Hidehiko" uniqKey="Honda H" first="Hidehiko" last="Honda">Hidehiko Honda</name>
</author>
<author><name sortKey="Inoue, Kiyoharu" sort="Inoue, Kiyoharu" uniqKey="Inoue K" first="Kiyoharu" last="Inoue">Kiyoharu Inoue</name>
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<author><name sortKey="Fukumitsu, Nobuyoshi" sort="Fukumitsu, Nobuyoshi" uniqKey="Fukumitsu N" first="Nobuyoshi" last="Fukumitsu">Nobuyoshi Fukumitsu</name>
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<author><name sortKey="Abo, Masahiro" sort="Abo, Masahiro" uniqKey="Abo M" first="Masahiro" last="Abo">Masahiro Abo</name>
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<author><name sortKey="Kono, Yu" sort="Kono, Yu" uniqKey="Kono Y" first="Yu" last="Kono">Yu Kono</name>
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<author><name sortKey="Sengoku, Renpei" sort="Sengoku, Renpei" uniqKey="Sengoku R" first="Renpei" last="Sengoku">Renpei Sengoku</name>
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<author><name sortKey="Inoue, Kiyoharu" sort="Inoue, Kiyoharu" uniqKey="Inoue K" first="Kiyoharu" last="Inoue">Kiyoharu Inoue</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Myocardium (metabolism)</term>
<term>Parkinsonian Disorders (genetics)</term>
<term>Parkinsonian Disorders (radionuclide imaging)</term>
<term>Radionuclide Imaging</term>
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<front><div type="abstract" xml:lang="en">A decrease in myocardial uptake of iodine-123-labeled metaiodobenzylguanidine (123I-MIBG) has been reported in idiopathic Parkinson's disease (PD) using 123I-MIBG myocardial scintigraphy. However, the patient with autosomal recessive juvenile parkinsonism (AR-JP), caused by the parkin gene, presented here showed normal 123I-MIBG myocardial uptake, suggesting that AR-JP is a distinct disease entity from PD. Although the clinical features of AR-JP are sometimes quite similar to those of late-onset idiopathic PD, 123I-MIBG myocardial scintigraphy may be a powerful tool to differentiate PD from other parkinsonian syndromes, including AR-JP.</div>
</front>
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<Abstract><AbstractText>A decrease in myocardial uptake of iodine-123-labeled metaiodobenzylguanidine (123I-MIBG) has been reported in idiopathic Parkinson's disease (PD) using 123I-MIBG myocardial scintigraphy. However, the patient with autosomal recessive juvenile parkinsonism (AR-JP), caused by the parkin gene, presented here showed normal 123I-MIBG myocardial uptake, suggesting that AR-JP is a distinct disease entity from PD. Although the clinical features of AR-JP are sometimes quite similar to those of late-onset idiopathic PD, 123I-MIBG myocardial scintigraphy may be a powerful tool to differentiate PD from other parkinsonian syndromes, including AR-JP.</AbstractText>
<CopyrightInformation>Copyright 2005 Movement Disorder Society.</CopyrightInformation>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Preserved myocardial [123I]metaiodobenzylguanidine uptake in autosomal recessive juvenile parkinsonism: first case report.

Preserved myocardial [123I]metaiodobenzylguanidine uptake in autosomal recessive juvenile parkinsonism: first case report.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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Pour générer des pages wiki