MovDisordV3, PubMed, Corpus, bibRecord, 002E36

On-demand deep brain stimulation for essential tremor: a report on four cases.

Identifieur interne : 002E36 ( PubMed/Corpus ); précédent : 002E35; suivant : 002E37

On-demand deep brain stimulation for essential tremor: a report on four cases.

Auteurs : Martin Kronenbuerger ; Christoph Fromm ; Frank Block ; Volker A. Coenen ; Ina Rohde ; Veit Rohde ; Johannes Noth

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.

RBID : pubmed:16211619

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Deep Brain Stimulation (methods), Essential Tremor (therapy), Female, Humans, Male, Middle Aged, Questionnaires, Thalamus (pathology).
MESH :
- methods : Deep Brain Stimulation.
- pathology : Thalamus.
- therapy : Essential Tremor.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Questionnaires.

Abstract

Deep brain stimulation (DBS) is an established therapy for essential tremor (ET), but loss of efficacy due to tolerance can occur. Our objective was to evaluate if it is feasible to use DBS only on-demand and if this would prevent tolerance. We report on the effects of left-side thalamic DBS in 4 ET patients who were instructed to switch on stimulation only when using their right hand for motor tasks and were followed-up to 30 months after surgery. The patients were capable of using DBS only on-demand (DBS use of 22.0+/-13.5%/day). DBS led to a stable suppression of right arm tremor throughout the follow-up. No problems associated with tolerance such as tremor rebound or late therapy failure occurred. In comparison to publications stating that ET patients had been using DBS continuously during the daytime, the use of on-demand DBS saves battery life, which delays surgical replacement of the stimulator. Thus, on-demand DBS saves money, may help to prevent tolerance, and should be adopted for the long-term treatment of ET patients.

DOI: 10.1002/mds.20714
PubMed: 16211619

Links to Exploration step

pubmed:16211619

Le document en format XML

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<author><name sortKey="Kronenbuerger, Martin" sort="Kronenbuerger, Martin" uniqKey="Kronenbuerger M" first="Martin" last="Kronenbuerger">Martin Kronenbuerger</name>
<affiliation><nlm:affiliation>Department of Neurology, University Hospital, RWTH Aachen, Germany. martin_kronenbuerger@web.de</nlm:affiliation>
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<author><name sortKey="Fromm, Christoph" sort="Fromm, Christoph" uniqKey="Fromm C" first="Christoph" last="Fromm">Christoph Fromm</name>
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<author><name sortKey="Block, Frank" sort="Block, Frank" uniqKey="Block F" first="Frank" last="Block">Frank Block</name>
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<author><name sortKey="Coenen, Volker A" sort="Coenen, Volker A" uniqKey="Coenen V" first="Volker A" last="Coenen">Volker A. Coenen</name>
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<author><name sortKey="Rohde, Ina" sort="Rohde, Ina" uniqKey="Rohde I" first="Ina" last="Rohde">Ina Rohde</name>
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<author><name sortKey="Rohde, Veit" sort="Rohde, Veit" uniqKey="Rohde V" first="Veit" last="Rohde">Veit Rohde</name>
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<front><div type="abstract" xml:lang="en">Deep brain stimulation (DBS) is an established therapy for essential tremor (ET), but loss of efficacy due to tolerance can occur. Our objective was to evaluate if it is feasible to use DBS only on-demand and if this would prevent tolerance. We report on the effects of left-side thalamic DBS in 4 ET patients who were instructed to switch on stimulation only when using their right hand for motor tasks and were followed-up to 30 months after surgery. The patients were capable of using DBS only on-demand (DBS use of 22.0+/-13.5%/day). DBS led to a stable suppression of right arm tremor throughout the follow-up. No problems associated with tolerance such as tremor rebound or late therapy failure occurred. In comparison to publications stating that ET patients had been using DBS continuously during the daytime, the use of on-demand DBS saves battery life, which delays surgical replacement of the stimulator. Thus, on-demand DBS saves money, may help to prevent tolerance, and should be adopted for the long-term treatment of ET patients.</div>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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	Movement Disorders (revue)
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Movement Disorders (revue)

On-demand deep brain stimulation for essential tremor: a report on four cases.

On-demand deep brain stimulation for essential tremor: a report on four cases.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki