Movement Disorders (revue)

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Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation.

Identifieur interne : 002C65 ( PubMed/Corpus ); précédent : 002C64; suivant : 002C66

Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation.

Auteurs : Erika Driver-Dunckley ; Virgilio Gerald H. Evidente ; Charles H. Adler ; Renee Hillman ; Jose Hernandez ; Geoffrey Fletcher ; Mark K. Lyons

Source :

RBID : pubmed:16671093

English descriptors

Abstract

We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.

DOI: 10.1002/mds.20911
PubMed: 16671093

Links to Exploration step

pubmed:16671093

Le document en format XML

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<name sortKey="Driver Dunckley, Erika" sort="Driver Dunckley, Erika" uniqKey="Driver Dunckley E" first="Erika" last="Driver-Dunckley">Erika Driver-Dunckley</name>
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<nlm:affiliation>Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA.</nlm:affiliation>
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<name sortKey="Evidente, Virgilio Gerald H" sort="Evidente, Virgilio Gerald H" uniqKey="Evidente V" first="Virgilio Gerald H" last="Evidente">Virgilio Gerald H. Evidente</name>
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<name sortKey="Hernandez, Jose" sort="Hernandez, Jose" uniqKey="Hernandez J" first="Jose" last="Hernandez">Jose Hernandez</name>
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<name sortKey="Fletcher, Geoffrey" sort="Fletcher, Geoffrey" uniqKey="Fletcher G" first="Geoffrey" last="Fletcher">Geoffrey Fletcher</name>
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<term>Levodopa (therapeutic use)</term>
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<term>Middle Aged</term>
<term>Parkinson Disease (drug therapy)</term>
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<div type="abstract" xml:lang="en">We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.</div>
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