Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.
Identifieur interne : 002A80 ( PubMed/Corpus ); précédent : 002A79; suivant : 002A81Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.
Auteurs : Annu Aggarwal ; Sachin Vaidya ; Samir Shah ; Joshita Singh ; Shrinivas Desai ; Mohit BhattSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
English descriptors
- KwdEn :
- Adult, Antiparkinson Agents (adverse effects), Female, Globus Pallidus (pathology), Humans, Levodopa (adverse effects), Liver Failure, Acute (complications), Liver Failure, Acute (pathology), Magnetic Resonance Imaging, Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (pathology), Parkinsonian Disorders (drug therapy), Parkinsonian Disorders (etiology), Parkinsonian Disorders (pathology).
- MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- chemically induced : Parkinson Disease, Secondary.
- complications : Liver Failure, Acute.
- drug therapy : Parkinsonian Disorders.
- etiology : Parkinsonian Disorders.
- pathology : Globus Pallidus, Liver Failure, Acute, Parkinson Disease, Secondary, Parkinsonian Disorders.
- Adult, Female, Humans, Magnetic Resonance Imaging.
Abstract
We report on a young woman who survived acute liver failure (ALF) without liver transplant. During the ALF, she developed a disabling, levodopa-unresponsive, symmetrical Parkinsonism. This was characterized by severe bradykinesia, mild rigidity, mutism, and prominent gait impairment. Magnetic resonance imaging (MRI) showed bilateral T1W pallidal hyperintensities. Parkinsonism and MRI changes remitted in parallel with normalization of hepatic function. We implicate excessive pallidal manganese deposition secondary to ALF in the pathogenesis of this neuroradiological syndrome. Though hitherto unreported, we propose that Parkinsonism with T1W pallidal hyperintensities may not be uncommon in ALF.
DOI: 10.1002/mds.21096
PubMed: 16991145
Links to Exploration step
pubmed:16991145Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.</title><author><name sortKey="Aggarwal, Annu" sort="Aggarwal, Annu" uniqKey="Aggarwal A" first="Annu" last="Aggarwal">Annu Aggarwal</name><affiliation><nlm:affiliation>Movement Disorder Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, India.</nlm:affiliation></affiliation></author><author><name sortKey="Vaidya, Sachin" sort="Vaidya, Sachin" uniqKey="Vaidya S" first="Sachin" last="Vaidya">Sachin Vaidya</name></author><author><name sortKey="Shah, Samir" sort="Shah, Samir" uniqKey="Shah S" first="Samir" last="Shah">Samir Shah</name></author><author><name sortKey="Singh, Joshita" sort="Singh, Joshita" uniqKey="Singh J" first="Joshita" last="Singh">Joshita Singh</name></author><author><name sortKey="Desai, Shrinivas" sort="Desai, Shrinivas" uniqKey="Desai S" first="Shrinivas" last="Desai">Shrinivas Desai</name></author><author><name sortKey="Bhatt, Mohit" sort="Bhatt, Mohit" uniqKey="Bhatt M" first="Mohit" last="Bhatt">Mohit Bhatt</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="doi">10.1002/mds.21096</idno><idno type="RBID">pubmed:16991145</idno><idno type="pmid">16991145</idno><idno type="wicri:Area/PubMed/Corpus">002A80</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.</title><author><name sortKey="Aggarwal, Annu" sort="Aggarwal, Annu" uniqKey="Aggarwal A" first="Annu" last="Aggarwal">Annu Aggarwal</name><affiliation><nlm:affiliation>Movement Disorder Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, India.</nlm:affiliation></affiliation></author><author><name sortKey="Vaidya, Sachin" sort="Vaidya, Sachin" uniqKey="Vaidya S" first="Sachin" last="Vaidya">Sachin Vaidya</name></author><author><name sortKey="Shah, Samir" sort="Shah, Samir" uniqKey="Shah S" first="Samir" last="Shah">Samir Shah</name></author><author><name sortKey="Singh, Joshita" sort="Singh, Joshita" uniqKey="Singh J" first="Joshita" last="Singh">Joshita Singh</name></author><author><name sortKey="Desai, Shrinivas" sort="Desai, Shrinivas" uniqKey="Desai S" first="Shrinivas" last="Desai">Shrinivas Desai</name></author><author><name sortKey="Bhatt, Mohit" sort="Bhatt, Mohit" uniqKey="Bhatt M" first="Mohit" last="Bhatt">Mohit Bhatt</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Antiparkinson Agents (adverse effects)</term><term>Female</term><term>Globus Pallidus (pathology)</term><term>Humans</term><term>Levodopa (adverse effects)</term><term>Liver Failure, Acute (complications)</term><term>Liver Failure, Acute (pathology)</term><term>Magnetic Resonance Imaging</term><term>Parkinson Disease, Secondary (chemically induced)</term><term>Parkinson Disease, Secondary (pathology)</term><term>Parkinsonian Disorders (drug therapy)</term><term>Parkinsonian Disorders (etiology)</term><term>Parkinsonian Disorders (pathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term><term>Levodopa</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Parkinson Disease, Secondary</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Liver Failure, Acute</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Globus Pallidus</term><term>Liver Failure, Acute</term><term>Parkinson Disease, Secondary</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Female</term><term>Humans</term><term>Magnetic Resonance Imaging</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We report on a young woman who survived acute liver failure (ALF) without liver transplant. During the ALF, she developed a disabling, levodopa-unresponsive, symmetrical Parkinsonism. This was characterized by severe bradykinesia, mild rigidity, mutism, and prominent gait impairment. Magnetic resonance imaging (MRI) showed bilateral T1W pallidal hyperintensities. Parkinsonism and MRI changes remitted in parallel with normalization of hepatic function. We implicate excessive pallidal manganese deposition secondary to ALF in the pathogenesis of this neuroradiological syndrome. Though hitherto unreported, we propose that Parkinsonism with T1W pallidal hyperintensities may not be uncommon in ALF.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">16991145</PMID><DateCreated><Year>2006</Year><Month>12</Month><Day>05</Day></DateCreated><DateCompleted><Year>2007</Year><Month>02</Month><Day>20</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN><JournalIssue CitedMedium="Print"><Volume>21</Volume><Issue>11</Issue><PubDate><Year>2006</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.</ArticleTitle><Pagination><MedlinePgn>1986-90</MedlinePgn></Pagination><Abstract><AbstractText>We report on a young woman who survived acute liver failure (ALF) without liver transplant. During the ALF, she developed a disabling, levodopa-unresponsive, symmetrical Parkinsonism. This was characterized by severe bradykinesia, mild rigidity, mutism, and prominent gait impairment. Magnetic resonance imaging (MRI) showed bilateral T1W pallidal hyperintensities. Parkinsonism and MRI changes remitted in parallel with normalization of hepatic function. We implicate excessive pallidal manganese deposition secondary to ALF in the pathogenesis of this neuroradiological syndrome. Though hitherto unreported, we propose that Parkinsonism with T1W pallidal hyperintensities may not be uncommon in ALF.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Aggarwal</LastName><ForeName>Annu</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Movement Disorder Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vaidya</LastName><ForeName>Sachin</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Shah</LastName><ForeName>Samir</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Singh</LastName><ForeName>Joshita</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Desai</LastName><ForeName>Shrinivas</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Bhatt</LastName><ForeName>Mohit</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000978">Antiparkinson Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>46627O600J</RegistryNumber><NameOfSubstance UI="D007980">Levodopa</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000978">Antiparkinson Agents</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005917">Globus Pallidus</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007980">Levodopa</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017114">Liver Failure, Acute</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D008279">Magnetic Resonance Imaging</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010302">Parkinson Disease, Secondary</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000139">chemically induced</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020734">Parkinsonian Disorders</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000188">drug therapy</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2006</Year><Month>9</Month><Day>23</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>2</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2006</Year><Month>9</Month><Day>23</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1002/mds.21096</ArticleId><ArticleId IdType="pubmed">16991145</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A80 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 002A80 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:16991145
|texte= Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:16991145" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |