Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome).
Identifieur interne : 002597 ( PubMed/Corpus ); précédent : 002596; suivant : 002598Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome).
Auteurs : Jill L. Ostrem ; William J. Marks ; Monica M. Volz ; Susan L. Heath ; Philip A. StarrSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.
English descriptors
- KwdEn :
- Adult, Aged, Deep Brain Stimulation (adverse effects), Deep Brain Stimulation (instrumentation), Electrodes, Implanted, Female, Follow-Up Studies, Globus Pallidus (physiopathology), Humans, Male, Meige Syndrome (physiopathology), Meige Syndrome (therapy), Microcomputers, Middle Aged, Neurologic Examination, Pilot Projects, Pyramidal Tracts (physiopathology), Torticollis (physiopathology), Torticollis (therapy), Treatment Outcome.
- MESH :
- adverse effects : Deep Brain Stimulation.
- instrumentation : Deep Brain Stimulation.
- physiopathology : Globus Pallidus, Meige Syndrome, Pyramidal Tracts, Torticollis.
- therapy : Meige Syndrome, Torticollis.
- Adult, Aged, Electrodes, Implanted, Female, Follow-Up Studies, Humans, Male, Microcomputers, Middle Aged, Neurologic Examination, Pilot Projects, Treatment Outcome.
Abstract
Idiopathic cranial-cervical dystonia (ICCD) is an adult-onset dystonia syndrome affecting orbicularis oculi, facial, oromandibular, and cervical musculature. ICCD is frequently difficult to treat medically. Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a highly effective treatment for idiopathic generalized dystonia, however less is known about the effect of GPi DBS on ICCD. In this article, we present the results from a pilot study assessing the effect of GPi DBS in a series of patients with ICCD. Six patients underwent bilateral stereotactic implantation of DBS leads into the sensorimotor GPi. Patients were evaluated with the Burke-Fahn-Marsden dystonia rating scale (BFMDRS) and Toronto western spamodic torticollis rating scale (TWSTRS) before surgery and 6 months postoperatively. At 6 months, patients showed a 72% mean improvement in the BFMDRS total movement score (P < 0.028, Wilcoxin signed rank test). The mean BFMDRS disability score showed a trend toward improvement (P < 0.06). The total TWSTRS score improved 54% (P < 0.043). Despite improvement in dystonia, mild worsening of motor function was reported in previously nondystonic body regions with stimulation in 4 patients. Although GPi DBS was effective in these patients, the influence of GPi DBS on nondystonic body regions deserves further investigation.
DOI: 10.1002/mds.21580
PubMed: 17618522
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pubmed:17618522Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome).</title><author><name sortKey="Ostrem, Jill L" sort="Ostrem, Jill L" uniqKey="Ostrem J" first="Jill L" last="Ostrem">Jill L. Ostrem</name><affiliation><nlm:affiliation>Department of Neurology, University of California, San Francisco, California 94143, USA. jill.ostrem@ucsf.edu</nlm:affiliation></affiliation></author><author><name sortKey="Marks, William J" sort="Marks, William J" uniqKey="Marks W" first="William J" last="Marks">William J. Marks</name></author><author><name sortKey="Volz, Monica M" sort="Volz, Monica M" uniqKey="Volz M" first="Monica M" last="Volz">Monica M. Volz</name></author><author><name sortKey="Heath, Susan L" sort="Heath, Susan L" uniqKey="Heath S" first="Susan L" last="Heath">Susan L. Heath</name></author><author><name sortKey="Starr, Philip A" sort="Starr, Philip A" uniqKey="Starr P" first="Philip A" last="Starr">Philip A. Starr</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1002/mds.21580</idno><idno type="RBID">pubmed:17618522</idno><idno type="pmid">17618522</idno><idno type="wicri:Area/PubMed/Corpus">002597</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome).</title><author><name sortKey="Ostrem, Jill L" sort="Ostrem, Jill L" uniqKey="Ostrem J" first="Jill L" last="Ostrem">Jill L. Ostrem</name><affiliation><nlm:affiliation>Department of Neurology, University of California, San Francisco, California 94143, USA. jill.ostrem@ucsf.edu</nlm:affiliation></affiliation></author><author><name sortKey="Marks, William J" sort="Marks, William J" uniqKey="Marks W" first="William J" last="Marks">William J. Marks</name></author><author><name sortKey="Volz, Monica M" sort="Volz, Monica M" uniqKey="Volz M" first="Monica M" last="Volz">Monica M. Volz</name></author><author><name sortKey="Heath, Susan L" sort="Heath, Susan L" uniqKey="Heath S" first="Susan L" last="Heath">Susan L. Heath</name></author><author><name sortKey="Starr, Philip A" sort="Starr, Philip A" uniqKey="Starr P" first="Philip A" last="Starr">Philip A. Starr</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Deep Brain Stimulation (adverse effects)</term><term>Deep Brain Stimulation (instrumentation)</term><term>Electrodes, Implanted</term><term>Female</term><term>Follow-Up Studies</term><term>Globus Pallidus (physiopathology)</term><term>Humans</term><term>Male</term><term>Meige Syndrome (physiopathology)</term><term>Meige Syndrome (therapy)</term><term>Microcomputers</term><term>Middle Aged</term><term>Neurologic Examination</term><term>Pilot Projects</term><term>Pyramidal Tracts (physiopathology)</term><term>Torticollis (physiopathology)</term><term>Torticollis (therapy)</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Globus Pallidus</term><term>Meige Syndrome</term><term>Pyramidal Tracts</term><term>Torticollis</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Meige Syndrome</term><term>Torticollis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Electrodes, Implanted</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Microcomputers</term><term>Middle Aged</term><term>Neurologic Examination</term><term>Pilot Projects</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Idiopathic cranial-cervical dystonia (ICCD) is an adult-onset dystonia syndrome affecting orbicularis oculi, facial, oromandibular, and cervical musculature. ICCD is frequently difficult to treat medically. Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a highly effective treatment for idiopathic generalized dystonia, however less is known about the effect of GPi DBS on ICCD. In this article, we present the results from a pilot study assessing the effect of GPi DBS in a series of patients with ICCD. Six patients underwent bilateral stereotactic implantation of DBS leads into the sensorimotor GPi. Patients were evaluated with the Burke-Fahn-Marsden dystonia rating scale (BFMDRS) and Toronto western spamodic torticollis rating scale (TWSTRS) before surgery and 6 months postoperatively. At 6 months, patients showed a 72% mean improvement in the BFMDRS total movement score (P < 0.028, Wilcoxin signed rank test). The mean BFMDRS disability score showed a trend toward improvement (P < 0.06). The total TWSTRS score improved 54% (P < 0.043). Despite improvement in dystonia, mild worsening of motor function was reported in previously nondystonic body regions with stimulation in 4 patients. Although GPi DBS was effective in these patients, the influence of GPi DBS on nondystonic body regions deserves further investigation.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">17618522</PMID><DateCreated><Year>2007</Year><Month>11</Month><Day>05</Day></DateCreated><DateCompleted><Year>2008</Year><Month>03</Month><Day>21</Day></DateCompleted><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN><JournalIssue CitedMedium="Print"><Volume>22</Volume><Issue>13</Issue><PubDate><Year>2007</Year><Month>Oct</Month><Day>15</Day></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Pallidal deep brain stimulation in patients with cranial-cervical dystonia (Meige syndrome).</ArticleTitle><Pagination><MedlinePgn>1885-91</MedlinePgn></Pagination><Abstract><AbstractText>Idiopathic cranial-cervical dystonia (ICCD) is an adult-onset dystonia syndrome affecting orbicularis oculi, facial, oromandibular, and cervical musculature. ICCD is frequently difficult to treat medically. Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a highly effective treatment for idiopathic generalized dystonia, however less is known about the effect of GPi DBS on ICCD. In this article, we present the results from a pilot study assessing the effect of GPi DBS in a series of patients with ICCD. Six patients underwent bilateral stereotactic implantation of DBS leads into the sensorimotor GPi. Patients were evaluated with the Burke-Fahn-Marsden dystonia rating scale (BFMDRS) and Toronto western spamodic torticollis rating scale (TWSTRS) before surgery and 6 months postoperatively. At 6 months, patients showed a 72% mean improvement in the BFMDRS total movement score (P < 0.028, Wilcoxin signed rank test). The mean BFMDRS disability score showed a trend toward improvement (P < 0.06). The total TWSTRS score improved 54% (P < 0.043). Despite improvement in dystonia, mild worsening of motor function was reported in previously nondystonic body regions with stimulation in 4 patients. Although GPi DBS was effective in these patients, the influence of GPi DBS on nondystonic body regions deserves further investigation.</AbstractText><CopyrightInformation>2007 Movement Disorder Society</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ostrem</LastName><ForeName>Jill L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Department of Neurology, University of California, San Francisco, California 94143, USA. jill.ostrem@ucsf.edu</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marks</LastName><ForeName>William J</ForeName><Initials>WJ</Initials><Suffix>Jr</Suffix></Author><Author ValidYN="Y"><LastName>Volz</LastName><ForeName>Monica M</ForeName><Initials>MM</Initials></Author><Author ValidYN="Y"><LastName>Heath</LastName><ForeName>Susan L</ForeName><Initials>SL</Initials></Author><Author ValidYN="Y"><LastName>Starr</LastName><ForeName>Philip A</ForeName><Initials>PA</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>K08</GrantID><Agency>PHS HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D046690">Deep Brain Stimulation</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000295">instrumentation</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004567">Electrodes, Implanted</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005500">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005917">Globus Pallidus</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008538">Meige Syndrome</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000628">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008838">Microcomputers</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009460">Neurologic Examination</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010865">Pilot Projects</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011712">Pyramidal Tracts</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014103">Torticollis</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000628">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>7</Month><Day>10</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2008</Year><Month>3</Month><Day>22</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>7</Month><Day>10</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1002/mds.21580</ArticleId><ArticleId IdType="pubmed">17618522</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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