MovDisordV3, PubMed, Corpus, bibRecord, 002031

The use of smell identification tests in the diagnosis of Parkinson's disease in Brazil.

Identifieur interne : 002031 ( PubMed/Corpus ); précédent : 002030; suivant : 002032

The use of smell identification tests in the diagnosis of Parkinson's disease in Brazil.

Auteurs : Laura Silveira-Moriyama ; Margarete De Jesus Carvalho ; Regina Katzenschlager ; Aviva Petrie ; Ronald Ranvaud ; Egberto Reis Barbosa ; Andrew J. Lees

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.

RBID : pubmed:18785265

English descriptors

KwdEn :
- Adult, Brazil, Discrimination (Psychology) (physiology), Female, Humans, Logistic Models, Male, Middle Aged, Neuropsychological Tests, Odors, Parkinson Disease (diagnosis), Parkinson Disease (physiopathology), Smell (physiology).
MESH :
- geographic : Brazil.
- diagnosis : Parkinson Disease.
- physiology : Discrimination (Psychology), Smell.
- physiopathology : Parkinson Disease.
- Adult, Female, Humans, Logistic Models, Male, Middle Aged, Neuropsychological Tests, Odors.

Abstract

Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls). The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.

DOI: 10.1002/mds.22241
PubMed: 18785265

Links to Exploration step

pubmed:18785265

Le document en format XML

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<author><name sortKey="Silveira Moriyama, Laura" sort="Silveira Moriyama, Laura" uniqKey="Silveira Moriyama L" first="Laura" last="Silveira-Moriyama">Laura Silveira-Moriyama</name>
<affiliation><nlm:affiliation>Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, London, United Kingdom.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Carvalho, Margarete De Jesus" sort="Carvalho, Margarete De Jesus" uniqKey="Carvalho M" first="Margarete De Jesus" last="Carvalho">Margarete De Jesus Carvalho</name>
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<author><name sortKey="Katzenschlager, Regina" sort="Katzenschlager, Regina" uniqKey="Katzenschlager R" first="Regina" last="Katzenschlager">Regina Katzenschlager</name>
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<author><name sortKey="Petrie, Aviva" sort="Petrie, Aviva" uniqKey="Petrie A" first="Aviva" last="Petrie">Aviva Petrie</name>
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<author><name sortKey="Ranvaud, Ronald" sort="Ranvaud, Ronald" uniqKey="Ranvaud R" first="Ronald" last="Ranvaud">Ronald Ranvaud</name>
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<author><name sortKey="Barbosa, Egberto Reis" sort="Barbosa, Egberto Reis" uniqKey="Barbosa E" first="Egberto Reis" last="Barbosa">Egberto Reis Barbosa</name>
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<author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J" last="Lees">Andrew J. Lees</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">The use of smell identification tests in the diagnosis of Parkinson's disease in Brazil.</title>
<author><name sortKey="Silveira Moriyama, Laura" sort="Silveira Moriyama, Laura" uniqKey="Silveira Moriyama L" first="Laura" last="Silveira-Moriyama">Laura Silveira-Moriyama</name>
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<author><name sortKey="Carvalho, Margarete De Jesus" sort="Carvalho, Margarete De Jesus" uniqKey="Carvalho M" first="Margarete De Jesus" last="Carvalho">Margarete De Jesus Carvalho</name>
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<author><name sortKey="Katzenschlager, Regina" sort="Katzenschlager, Regina" uniqKey="Katzenschlager R" first="Regina" last="Katzenschlager">Regina Katzenschlager</name>
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<author><name sortKey="Ranvaud, Ronald" sort="Ranvaud, Ronald" uniqKey="Ranvaud R" first="Ronald" last="Ranvaud">Ronald Ranvaud</name>
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<term>Humans</term>
<term>Logistic Models</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Odors</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (physiopathology)</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Female</term>
<term>Humans</term>
<term>Logistic Models</term>
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<front><div type="abstract" xml:lang="en">Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls). The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.</div>
</front>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>The use of smell identification tests in the diagnosis of Parkinson's disease in Brazil.</ArticleTitle>
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<Abstract><AbstractText>Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls). The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.</AbstractText>
<CopyrightInformation>(c) 2008 Movement Disorder Society.</CopyrightInformation>
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<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Mov Disord. 2010 Mar 15;25(4):510-1</RefSource>
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Movement Disorders (revue)

The use of smell identification tests in the diagnosis of Parkinson's disease in Brazil.

The use of smell identification tests in the diagnosis of Parkinson's disease in Brazil.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki