MovDisordV3, PubMed, Corpus, bibRecord, 001C97

Progression of ataxia in patients with Machado-Joseph disease.

Identifieur interne : 001C97 ( PubMed/Corpus ); précédent : 001C96; suivant : 001C98

Progression of ataxia in patients with Machado-Joseph disease.

Auteurs : Marcondes C. França ; Anelyssa D'Abreu ; Anamarli Nucci ; Fernando Cendes ; Iscia Lopes-Cendes

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2009.

RBID : pubmed:19441132

English descriptors

KwdEn :
- Adult, Aged, Ataxia (etiology), Brazil, Disability Evaluation, Disease Progression, Female, Humans, Machado-Joseph Disease (complications), Machado-Joseph Disease (genetics), Male, Middle Aged, Prospective Studies, Severity of Illness Index, Trinucleotide Repeat Expansion (genetics), Young Adult.
MESH :
- geographic : Brazil.
- complications : Machado-Joseph Disease.
- etiology : Ataxia.
- genetics : Machado-Joseph Disease, Trinucleotide Repeat Expansion.
- Adult, Aged, Disability Evaluation, Disease Progression, Female, Humans, Male, Middle Aged, Prospective Studies, Severity of Illness Index, Young Adult.

Abstract

Although ataxia is the most distressing manifestation of Machado-Joseph disease (MJD), little is known about its natural history. Therefore, we prospectively followed a cohort of patients with MJD for 13 months to characterize the progression of ataxia and identify its contributory factors. The international cooperative ataxia rating scale (ICARS) was used to estimate severity of ataxia at baseline and at follow-up. Thirty-four patients were enrolled in the study, 22 of whom were men. Mean age at onset of the disease was 34.7 years and length of expanded CAG repeat was 66. Mean ICARS scores at baseline was 37.6 and at follow-up was 42.7 (P < 0.001). Multivariate analysis did not find significant association of progression of disease and age at disease onset, length of expanded (CAG), or duration of disease.

DOI: 10.1002/mds.22627
PubMed: 19441132

Links to Exploration step

pubmed:19441132

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Progression of ataxia in patients with Machado-Joseph disease.</title>
<author><name sortKey="Franca, Marcondes C" sort="Franca, Marcondes C" uniqKey="Franca M" first="Marcondes C" last="França">Marcondes C. França</name>
<affiliation><nlm:affiliation>Department of Neurology, University of Campinas, São Paulo, Brazil.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="D Abreu, Anelyssa" sort="D Abreu, Anelyssa" uniqKey="D Abreu A" first="Anelyssa" last="D'Abreu">Anelyssa D'Abreu</name>
</author>
<author><name sortKey="Nucci, Anamarli" sort="Nucci, Anamarli" uniqKey="Nucci A" first="Anamarli" last="Nucci">Anamarli Nucci</name>
</author>
<author><name sortKey="Cendes, Fernando" sort="Cendes, Fernando" uniqKey="Cendes F" first="Fernando" last="Cendes">Fernando Cendes</name>
</author>
<author><name sortKey="Lopes Cendes, Iscia" sort="Lopes Cendes, Iscia" uniqKey="Lopes Cendes I" first="Iscia" last="Lopes-Cendes">Iscia Lopes-Cendes</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2009">2009</date>
<idno type="doi">10.1002/mds.22627</idno>
<idno type="RBID">pubmed:19441132</idno>
<idno type="pmid">19441132</idno>
<idno type="wicri:Area/PubMed/Corpus">001C97</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Progression of ataxia in patients with Machado-Joseph disease.</title>
<author><name sortKey="Franca, Marcondes C" sort="Franca, Marcondes C" uniqKey="Franca M" first="Marcondes C" last="França">Marcondes C. França</name>
<affiliation><nlm:affiliation>Department of Neurology, University of Campinas, São Paulo, Brazil.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="D Abreu, Anelyssa" sort="D Abreu, Anelyssa" uniqKey="D Abreu A" first="Anelyssa" last="D'Abreu">Anelyssa D'Abreu</name>
</author>
<author><name sortKey="Nucci, Anamarli" sort="Nucci, Anamarli" uniqKey="Nucci A" first="Anamarli" last="Nucci">Anamarli Nucci</name>
</author>
<author><name sortKey="Cendes, Fernando" sort="Cendes, Fernando" uniqKey="Cendes F" first="Fernando" last="Cendes">Fernando Cendes</name>
</author>
<author><name sortKey="Lopes Cendes, Iscia" sort="Lopes Cendes, Iscia" uniqKey="Lopes Cendes I" first="Iscia" last="Lopes-Cendes">Iscia Lopes-Cendes</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2009" type="published">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Ataxia (etiology)</term>
<term>Brazil</term>
<term>Disability Evaluation</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Machado-Joseph Disease (complications)</term>
<term>Machado-Joseph Disease (genetics)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Severity of Illness Index</term>
<term>Trinucleotide Repeat Expansion (genetics)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Brazil</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Machado-Joseph Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Ataxia</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Machado-Joseph Disease</term>
<term>Trinucleotide Repeat Expansion</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Disability Evaluation</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Severity of Illness Index</term>
<term>Young Adult</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Although ataxia is the most distressing manifestation of Machado-Joseph disease (MJD), little is known about its natural history. Therefore, we prospectively followed a cohort of patients with MJD for 13 months to characterize the progression of ataxia and identify its contributory factors. The international cooperative ataxia rating scale (ICARS) was used to estimate severity of ataxia at baseline and at follow-up. Thirty-four patients were enrolled in the study, 22 of whom were men. Mean age at onset of the disease was 34.7 years and length of expanded CAG repeat was 66. Mean ICARS scores at baseline was 37.6 and at follow-up was 42.7 (P < 0.001). Multivariate analysis did not find significant association of progression of disease and age at disease onset, length of expanded (CAG), or duration of disease.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">19441132</PMID>
<DateCreated><Year>2009</Year>
<Month>08</Month>
<Day>03</Day>
</DateCreated>
<DateCompleted><Year>2009</Year>
<Month>10</Month>
<Day>21</Day>
</DateCompleted>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>24</Volume>
<Issue>9</Issue>
<PubDate><Year>2009</Year>
<Month>Jul</Month>
<Day>15</Day>
</PubDate>
</JournalIssue>
<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>Progression of ataxia in patients with Machado-Joseph disease.</ArticleTitle>
<Pagination><MedlinePgn>1387-90</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.22627</ELocationID>
<Abstract><AbstractText>Although ataxia is the most distressing manifestation of Machado-Joseph disease (MJD), little is known about its natural history. Therefore, we prospectively followed a cohort of patients with MJD for 13 months to characterize the progression of ataxia and identify its contributory factors. The international cooperative ataxia rating scale (ICARS) was used to estimate severity of ataxia at baseline and at follow-up. Thirty-four patients were enrolled in the study, 22 of whom were men. Mean age at onset of the disease was 34.7 years and length of expanded CAG repeat was 66. Mean ICARS scores at baseline was 37.6 and at follow-up was 42.7 (P < 0.001). Multivariate analysis did not find significant association of progression of disease and age at disease onset, length of expanded (CAG), or duration of disease.</AbstractText>
<CopyrightInformation>2009 Movement Disorder Society.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>França</LastName>
<ForeName>Marcondes C</ForeName>
<Initials>MC</Initials>
<Suffix>Jr</Suffix>
<AffiliationInfo><Affiliation>Department of Neurology, University of Campinas, São Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>D'Abreu</LastName>
<ForeName>Anelyssa</ForeName>
<Initials>A</Initials>
</Author>
<Author ValidYN="Y"><LastName>Nucci</LastName>
<ForeName>Anamarli</ForeName>
<Initials>A</Initials>
</Author>
<Author ValidYN="Y"><LastName>Cendes</LastName>
<ForeName>Fernando</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Lopes-Cendes</LastName>
<ForeName>Iscia</ForeName>
<Initials>I</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001259">Ataxia</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000209">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" Type="Geographic" UI="D001938">Brazil</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004185">Disability Evaluation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D018450">Disease Progression</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D017827">Machado-Joseph Disease</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000150">complications</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011446">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012720">Severity of Illness Index</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019680">Trinucleotide Repeat Expansion</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D055815">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year>
<Month>5</Month>
<Day>15</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2009</Year>
<Month>5</Month>
<Day>15</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2009</Year>
<Month>10</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="doi">10.1002/mds.22627</ArticleId>
<ArticleId IdType="pubmed">19441132</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PubMed/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C97 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 001C97 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    PubMed
   |étape=   Corpus
   |type=    RBID
   |clé=     pubmed:19441132
   |texte=   Progression of ataxia in patients with Machado-Joseph disease.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i   -Sk "pubmed:19441132" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd   \
       | NlmPubMed2Wicri -a MovDisordV3

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Progression of ataxia in patients with Machado-Joseph disease.

Progression of ataxia in patients with Machado-Joseph disease.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki