Movement Disorders (revue)

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Diffusion tensor imaging of freezing of gait in patients with white matter changes.

Identifieur interne : 000F40 ( PubMed/Corpus ); précédent : 000F39; suivant : 000F41

Diffusion tensor imaging of freezing of gait in patients with white matter changes.

Auteurs : Jinyoung Youn ; Jin Whan Cho ; Won Yong Lee ; Gyeong-Moon Kim ; Sung Tae Kim ; Hee-Tae Kim

Source :

RBID : pubmed:22162037

English descriptors

Abstract

Freezing of gait is a common and disabling symptom of parkinsonism. However, the corresponding anatomic structures have yet to be clearly elucidated.

DOI: 10.1002/mds.24034
PubMed: 22162037

Links to Exploration step

pubmed:22162037

Le document en format XML

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<name sortKey="Youn, Jinyoung" sort="Youn, Jinyoung" uniqKey="Youn J" first="Jinyoung" last="Youn">Jinyoung Youn</name>
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<nlm:affiliation>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:affiliation>
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<name sortKey="Cho, Jin Whan" sort="Cho, Jin Whan" uniqKey="Cho J" first="Jin Whan" last="Cho">Jin Whan Cho</name>
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<name sortKey="Lee, Won Yong" sort="Lee, Won Yong" uniqKey="Lee W" first="Won Yong" last="Lee">Won Yong Lee</name>
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<name sortKey="Kim, Gyeong Moon" sort="Kim, Gyeong Moon" uniqKey="Kim G" first="Gyeong-Moon" last="Kim">Gyeong-Moon Kim</name>
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<name sortKey="Kim, Sung Tae" sort="Kim, Sung Tae" uniqKey="Kim S" first="Sung Tae" last="Kim">Sung Tae Kim</name>
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<name sortKey="Kim, Hee Tae" sort="Kim, Hee Tae" uniqKey="Kim H" first="Hee-Tae" last="Kim">Hee-Tae Kim</name>
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<nlm:affiliation>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:affiliation>
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<name sortKey="Cho, Jin Whan" sort="Cho, Jin Whan" uniqKey="Cho J" first="Jin Whan" last="Cho">Jin Whan Cho</name>
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<name sortKey="Lee, Won Yong" sort="Lee, Won Yong" uniqKey="Lee W" first="Won Yong" last="Lee">Won Yong Lee</name>
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<name sortKey="Kim, Gyeong Moon" sort="Kim, Gyeong Moon" uniqKey="Kim G" first="Gyeong-Moon" last="Kim">Gyeong-Moon Kim</name>
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<name sortKey="Kim, Sung Tae" sort="Kim, Sung Tae" uniqKey="Kim S" first="Sung Tae" last="Kim">Sung Tae Kim</name>
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<name sortKey="Kim, Hee Tae" sort="Kim, Hee Tae" uniqKey="Kim H" first="Hee-Tae" last="Kim">Hee-Tae Kim</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
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<term>Anisotropy</term>
<term>Brain (pathology)</term>
<term>Brain (physiopathology)</term>
<term>Diffusion Tensor Imaging</term>
<term>Female</term>
<term>Gait Disorders, Neurologic (pathology)</term>
<term>Gait Disorders, Neurologic (physiopathology)</term>
<term>Humans</term>
<term>Image Processing, Computer-Assisted</term>
<term>Male</term>
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<term>Brain</term>
<term>Gait Disorders, Neurologic</term>
<term>Nerve Fibers, Myelinated</term>
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<term>Nerve Fibers, Myelinated</term>
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<term>Brain</term>
<term>Gait Disorders, Neurologic</term>
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<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Anisotropy</term>
<term>Diffusion Tensor Imaging</term>
<term>Female</term>
<term>Humans</term>
<term>Image Processing, Computer-Assisted</term>
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<front>
<div type="abstract" xml:lang="en">Freezing of gait is a common and disabling symptom of parkinsonism. However, the corresponding anatomic structures have yet to be clearly elucidated.</div>
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<ISSN IssnType="Electronic">1531-8257</ISSN>
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<Volume>27</Volume>
<Issue>6</Issue>
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<Month>May</Month>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Diffusion tensor imaging of freezing of gait in patients with white matter changes.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Freezing of gait is a common and disabling symptom of parkinsonism. However, the corresponding anatomic structures have yet to be clearly elucidated.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We performed diffusion tensor imaging on 40 subjects with white matter changes. We compared apparent diffusion coefficient values and fraction anisotropy values of 7 candidate anatomic structures between 14 patients with freezing of gait (freezing of gait group) and 26 without freezing of gait (control group).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Fraction anisotropy values of the bilateral pedunculopontine nucleus, bilateral superior premotor cortex, right orbitofrontal area, and left supplement motor area were significantly lower in the freezing of gait group than in the control group. In contrast, there were no significant differences in apparent diffusion coefficient values between freezing of gait and control groups.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our findings suggest that the bilateral pedunculopontine nucleus, bilateral superior premotor cortex, right orbitofrontal area, and left supplement motor area are closely related to freezing of gait.</AbstractText>
<CopyrightInformation>Copyright © 2011 Movement Disorder Society.</CopyrightInformation>
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