Movement Disorders (revue)

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Imaging measures predict progression in progressive supranuclear palsy.

Identifieur interne : 000E35 ( PubMed/Corpus ); précédent : 000E34; suivant : 000E36

Imaging measures predict progression in progressive supranuclear palsy.

Auteurs : Jennifer L. Whitwell ; Jia Xu ; Jay Mandrekar ; Jeffrey L. Gunter ; Clifford R. Jack ; Keith A. Josephs

Source :

RBID : pubmed:22415715

English descriptors

Abstract

The aim of this work was to determine whether the progressive supranuclear palsy rating scale, a measure of disease severity, is associated with neuroanatomical changes in progressive supranuclear palsy.

DOI: 10.1002/mds.24970
PubMed: 22415715

Links to Exploration step

pubmed:22415715

Le document en format XML

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<title xml:lang="en">Imaging measures predict progression in progressive supranuclear palsy.</title>
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<name sortKey="Whitwell, Jennifer L" sort="Whitwell, Jennifer L" uniqKey="Whitwell J" first="Jennifer L" last="Whitwell">Jennifer L. Whitwell</name>
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<nlm:affiliation>Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA. whitwell.jennifer@mayo.edu</nlm:affiliation>
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<name sortKey="Xu, Jia" sort="Xu, Jia" uniqKey="Xu J" first="Jia" last="Xu">Jia Xu</name>
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<name sortKey="Mandrekar, Jay" sort="Mandrekar, Jay" uniqKey="Mandrekar J" first="Jay" last="Mandrekar">Jay Mandrekar</name>
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<name sortKey="Gunter, Jeffrey L" sort="Gunter, Jeffrey L" uniqKey="Gunter J" first="Jeffrey L" last="Gunter">Jeffrey L. Gunter</name>
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<name sortKey="Jack, Clifford R" sort="Jack, Clifford R" uniqKey="Jack C" first="Clifford R" last="Jack">Clifford R. Jack</name>
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<name sortKey="Josephs, Keith A" sort="Josephs, Keith A" uniqKey="Josephs K" first="Keith A" last="Josephs">Keith A. Josephs</name>
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<title xml:lang="en">Imaging measures predict progression in progressive supranuclear palsy.</title>
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<nlm:affiliation>Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA. whitwell.jennifer@mayo.edu</nlm:affiliation>
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<name sortKey="Xu, Jia" sort="Xu, Jia" uniqKey="Xu J" first="Jia" last="Xu">Jia Xu</name>
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<name sortKey="Mandrekar, Jay" sort="Mandrekar, Jay" uniqKey="Mandrekar J" first="Jay" last="Mandrekar">Jay Mandrekar</name>
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<name sortKey="Gunter, Jeffrey L" sort="Gunter, Jeffrey L" uniqKey="Gunter J" first="Jeffrey L" last="Gunter">Jeffrey L. Gunter</name>
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<name sortKey="Jack, Clifford R" sort="Jack, Clifford R" uniqKey="Jack C" first="Clifford R" last="Jack">Clifford R. Jack</name>
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<name sortKey="Josephs, Keith A" sort="Josephs, Keith A" uniqKey="Josephs K" first="Keith A" last="Josephs">Keith A. Josephs</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
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<date when="2012" type="published">2012</date>
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<term>Aged</term>
<term>Anisotropy</term>
<term>Brain Mapping</term>
<term>Diffusion Tensor Imaging (methods)</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Image Processing, Computer-Assisted (methods)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Predictive Value of Tests</term>
<term>Supranuclear Palsy, Progressive (pathology)</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Diffusion Tensor Imaging</term>
<term>Image Processing, Computer-Assisted</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Anisotropy</term>
<term>Brain Mapping</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Predictive Value of Tests</term>
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<front>
<div type="abstract" xml:lang="en">The aim of this work was to determine whether the progressive supranuclear palsy rating scale, a measure of disease severity, is associated with neuroanatomical changes in progressive supranuclear palsy.</div>
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<DateCreated>
<Year>2013</Year>
<Month>01</Month>
<Day>03</Day>
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<DateCompleted>
<Year>2013</Year>
<Month>08</Month>
<Day>07</Day>
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<Journal>
<ISSN IssnType="Electronic">1531-8257</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>27</Volume>
<Issue>14</Issue>
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<Year>2012</Year>
<Month>Dec</Month>
</PubDate>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Imaging measures predict progression in progressive supranuclear palsy.</ArticleTitle>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The aim of this work was to determine whether the progressive supranuclear palsy rating scale, a measure of disease severity, is associated with neuroanatomical changes in progressive supranuclear palsy.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We recruited 22 subjects with probable progressive supranuclear palsy who completed the progressive supranuclear palsy rating scale at 2 time points. All subjects had magnetic resonance imaging and diffusion tensor imaging. Associations were assessed between whole brain volume, ventricular volume, midbrain area and superior cerebellar peduncle fractional anisotropy, and baseline/change of the progressive supranuclear palsy rating scale.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Superior cerebellar peduncle fractional anisotropy correlated with the total score and gait/midline subscore of the progressive supranuclear palsy rating scale. Whole brain volume, midbrain area, and disease duration predicted subsequent change over time in the gait/midline subscore of the progressive supranuclear palsy rating scale.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Imaging measures could be useful to help predict clinical progression in subjects with progressive supranuclear palsy.</AbstractText>
<CopyrightInformation>Copyright © 2012 Movement Disorder Society.</CopyrightInformation>
</Abstract>
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<ForeName>Jennifer L</ForeName>
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<RefSource>Mov Disord. 2012 Dec;27(14):1711-3</RefSource>
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<DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
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<DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
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<DescriptorName MajorTopicYN="N" UI="D011237">Predictive Value of Tests</DescriptorName>
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<DescriptorName MajorTopicYN="N" UI="D013494">Supranuclear Palsy, Progressive</DescriptorName>
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