Movement Disorders (revue)

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Validation of a screening battery to predict driving fitness in people with Parkinson's disease.

Identifieur interne : 000A31 ( PubMed/Corpus ); précédent : 000A30; suivant : 000A32

Validation of a screening battery to predict driving fitness in people with Parkinson's disease.

Auteurs : Hannes Devos ; Wim Vandenberghe ; Alice Nieuwboer ; Mark Tant ; Willy De Weerdt ; Jeffrey D. Dawson ; Ergun Y. Uc

Source :

RBID : pubmed:23436270

English descriptors

Abstract

We previously developed a short clinical battery, consisting of contrast sensitivity, Clinical Dementia Rating, the Unified Parkinson's Disease Rating Scale-motor section (UPDRS III), and disease duration, which correctly classified 90% of drivers with Parkinson's Disease (PD). The aim of this study was to validate that screening battery in a different sample of PD drivers.

DOI: 10.1002/mds.25387
PubMed: 23436270

Links to Exploration step

pubmed:23436270

Le document en format XML

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<title xml:lang="en">Validation of a screening battery to predict driving fitness in people with Parkinson's disease.</title>
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<name sortKey="Devos, Hannes" sort="Devos, Hannes" uniqKey="Devos H" first="Hannes" last="Devos">Hannes Devos</name>
<affiliation>
<nlm:affiliation>Department of Rehabilitation Sciences, KU Leuven, Heverlee, Belgium. hannes.devos@faber.kuleuven.be</nlm:affiliation>
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<author>
<name sortKey="Vandenberghe, Wim" sort="Vandenberghe, Wim" uniqKey="Vandenberghe W" first="Wim" last="Vandenberghe">Wim Vandenberghe</name>
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<name sortKey="Nieuwboer, Alice" sort="Nieuwboer, Alice" uniqKey="Nieuwboer A" first="Alice" last="Nieuwboer">Alice Nieuwboer</name>
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<name sortKey="Tant, Mark" sort="Tant, Mark" uniqKey="Tant M" first="Mark" last="Tant">Mark Tant</name>
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<name sortKey="De Weerdt, Willy" sort="De Weerdt, Willy" uniqKey="De Weerdt W" first="Willy" last="De Weerdt">Willy De Weerdt</name>
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<name sortKey="Dawson, Jeffrey D" sort="Dawson, Jeffrey D" uniqKey="Dawson J" first="Jeffrey D" last="Dawson">Jeffrey D. Dawson</name>
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<name sortKey="Uc, Ergun Y" sort="Uc, Ergun Y" uniqKey="Uc E" first="Ergun Y" last="Uc">Ergun Y. Uc</name>
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<name sortKey="De Weerdt, Willy" sort="De Weerdt, Willy" uniqKey="De Weerdt W" first="Willy" last="De Weerdt">Willy De Weerdt</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Automobile Driving</term>
<term>Computer Simulation</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Humans</term>
<term>Logistic Models</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neurologic Examination</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (psychology)</term>
<term>Predictive Value of Tests</term>
<term>Psychomotor Performance</term>
<term>Retrospective Studies</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en">
<term>Parkinson Disease</term>
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<term>Aged</term>
<term>Automobile Driving</term>
<term>Computer Simulation</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Humans</term>
<term>Logistic Models</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Predictive Value of Tests</term>
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<div type="abstract" xml:lang="en">We previously developed a short clinical battery, consisting of contrast sensitivity, Clinical Dementia Rating, the Unified Parkinson's Disease Rating Scale-motor section (UPDRS III), and disease duration, which correctly classified 90% of drivers with Parkinson's Disease (PD). The aim of this study was to validate that screening battery in a different sample of PD drivers.</div>
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<Month>May</Month>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>Validation of a screening battery to predict driving fitness in people with Parkinson's disease.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">We previously developed a short clinical battery, consisting of contrast sensitivity, Clinical Dementia Rating, the Unified Parkinson's Disease Rating Scale-motor section (UPDRS III), and disease duration, which correctly classified 90% of drivers with Parkinson's Disease (PD). The aim of this study was to validate that screening battery in a different sample of PD drivers.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Sixty drivers with PD were enrolled to validate our original screening battery to predict driving fitness decisions (pass-fail) by a state agency where drivers underwent detailed visual, cognitive, and on-road testing.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Twenty-four participants (40%) failed the driving evaluation. The screening battery correctly classified 46 (77%) participants (sensitivity and negative predictive value = 96%; specificity and positive predictive value = 64%). Adding other clinical predictors (e.g., age of onset, Hoehn-Yahr stage instead of UPDRS III) failed to improve the specificity of the model when the sensitivity was kept constant at 96%. However, a driving simulator evaluation improved the specificity of the model to 94%.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The original clinical battery proved to be a valid screening tool that accurately identifies fit drivers with PD and select those who need more detailed testing at specialized centers.</AbstractText>
<CopyrightInformation>Copyright © 2013 Movement Disorder Society.</CopyrightInformation>
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