Down-regulating α-synuclein for treating synucleopathies.
Identifieur interne : 000393 ( PubMed/Corpus ); précédent : 000392; suivant : 000394Down-regulating α-synuclein for treating synucleopathies.
Auteurs : Mathieu Bourdenx ; Benjamin Dehay ; Erwan BezardSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : RNA, Small Interfering.
- drug effects : Gene Expression Regulation.
- genetics : Mutation, alpha-Synuclein.
- metabolism : Brain, alpha-Synuclein.
- Animals, Humans.
DOI: 10.1002/mds.26028
PubMed: 25214445
Links to Exploration step
pubmed:25214445Le document en format XML
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<author><name sortKey="Bourdenx, Mathieu" sort="Bourdenx, Mathieu" uniqKey="Bourdenx M" first="Mathieu" last="Bourdenx">Mathieu Bourdenx</name>
<affiliation><nlm:affiliation>Institute of Neurodegenerative Diseases, University of Bordeaux, Centre National de la Recherche Scientifique Unité Mixte de Recherche, Bordeaux, France.</nlm:affiliation>
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<author><name sortKey="Dehay, Benjamin" sort="Dehay, Benjamin" uniqKey="Dehay B" first="Benjamin" last="Dehay">Benjamin Dehay</name>
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<author><name sortKey="Bezard, Erwan" sort="Bezard, Erwan" uniqKey="Bezard E" first="Erwan" last="Bezard">Erwan Bezard</name>
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<author><name sortKey="Dehay, Benjamin" sort="Dehay, Benjamin" uniqKey="Dehay B" first="Benjamin" last="Dehay">Benjamin Dehay</name>
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<author><name sortKey="Bezard, Erwan" sort="Bezard, Erwan" uniqKey="Bezard E" first="Erwan" last="Bezard">Erwan Bezard</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
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<term>Gene Expression Regulation (drug effects)</term>
<term>Humans</term>
<term>Mutation (genetics)</term>
<term>RNA, Small Interfering (administration & dosage)</term>
<term>alpha-Synuclein (genetics)</term>
<term>alpha-Synuclein (metabolism)</term>
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<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>RNA, Small Interfering</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Gene Expression Regulation</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Mutation</term>
<term>alpha-Synuclein</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Brain</term>
<term>alpha-Synuclein</term>
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<DateCompleted><Year>2015</Year>
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<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>29</Volume>
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<PubDate><Year>2014</Year>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Down-regulating α-synuclein for treating synucleopathies.</ArticleTitle>
<Pagination><MedlinePgn>1463-5</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.26028</ELocationID>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bourdenx</LastName>
<ForeName>Mathieu</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute of Neurodegenerative Diseases, University of Bordeaux, Centre National de la Recherche Scientifique Unité Mixte de Recherche, Bordeaux, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Dehay</LastName>
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<Author ValidYN="Y"><LastName>Bezard</LastName>
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<Language>eng</Language>
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<MedlineJournalInfo><Country>United States</Country>
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<CommentsCorrectionsList><CommentsCorrections RefType="CommentOn"><RefSource>Mov Disord. 2014 Oct;29(12):1476-85</RefSource>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Parkinson's disease</Keyword>
<Keyword MajorTopicYN="N">siRNA</Keyword>
<Keyword MajorTopicYN="N">therapeutic strategy</Keyword>
<Keyword MajorTopicYN="N">α-synuclein</Keyword>
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