A phase II, open-label evaluation of cysteamine tolerability in patients with Huntington's disease.
Identifieur interne : 000333 ( PubMed/Corpus ); précédent : 000332; suivant : 000334A phase II, open-label evaluation of cysteamine tolerability in patients with Huntington's disease.
Auteurs : Adriana Prundean ; Katia Youssov ; Sandrine Humbert ; Dominique Bonneau ; Christophe VernySource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Cysteamine.
- chemical , adverse effects : Cysteamine.
- chemical , therapeutic use : Cysteamine.
- drug therapy : Huntington Disease.
- Adolescent, Adult, Drug Tolerance, Humans, Middle Aged, Treatment Outcome, Young Adult.
DOI: 10.1002/mds.26101
PubMed: 25475049
Links to Exploration step
pubmed:25475049Le document en format XML
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<author><name sortKey="Prundean, Adriana" sort="Prundean, Adriana" uniqKey="Prundean A" first="Adriana" last="Prundean">Adriana Prundean</name>
<affiliation><nlm:affiliation>Centre de référence des maladies neurogénétiques, Centre Hospitalier Universitaire, Angers, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Youssov, Katia" sort="Youssov, Katia" uniqKey="Youssov K" first="Katia" last="Youssov">Katia Youssov</name>
</author>
<author><name sortKey="Humbert, Sandrine" sort="Humbert, Sandrine" uniqKey="Humbert S" first="Sandrine" last="Humbert">Sandrine Humbert</name>
</author>
<author><name sortKey="Bonneau, Dominique" sort="Bonneau, Dominique" uniqKey="Bonneau D" first="Dominique" last="Bonneau">Dominique Bonneau</name>
</author>
<author><name sortKey="Verny, Christophe" sort="Verny, Christophe" uniqKey="Verny C" first="Christophe" last="Verny">Christophe Verny</name>
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<author><name sortKey="Prundean, Adriana" sort="Prundean, Adriana" uniqKey="Prundean A" first="Adriana" last="Prundean">Adriana Prundean</name>
<affiliation><nlm:affiliation>Centre de référence des maladies neurogénétiques, Centre Hospitalier Universitaire, Angers, France.</nlm:affiliation>
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<author><name sortKey="Youssov, Katia" sort="Youssov, Katia" uniqKey="Youssov K" first="Katia" last="Youssov">Katia Youssov</name>
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<author><name sortKey="Humbert, Sandrine" sort="Humbert, Sandrine" uniqKey="Humbert S" first="Sandrine" last="Humbert">Sandrine Humbert</name>
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<author><name sortKey="Bonneau, Dominique" sort="Bonneau, Dominique" uniqKey="Bonneau D" first="Dominique" last="Bonneau">Dominique Bonneau</name>
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<author><name sortKey="Verny, Christophe" sort="Verny, Christophe" uniqKey="Verny C" first="Christophe" last="Verny">Christophe Verny</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2015" type="published">2015</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Cysteamine (administration & dosage)</term>
<term>Cysteamine (adverse effects)</term>
<term>Cysteamine (therapeutic use)</term>
<term>Drug Tolerance</term>
<term>Humans</term>
<term>Huntington Disease (drug therapy)</term>
<term>Middle Aged</term>
<term>Treatment Outcome</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Cysteamine</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Cysteamine</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Cysteamine</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Huntington Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Drug Tolerance</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Treatment Outcome</term>
<term>Young Adult</term>
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<Month>02</Month>
<Day>04</Day>
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<DateCompleted><Year>2015</Year>
<Month>10</Month>
<Day>22</Day>
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<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>30</Volume>
<Issue>2</Issue>
<PubDate><Year>2015</Year>
<Month>Feb</Month>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>A phase II, open-label evaluation of cysteamine tolerability in patients with Huntington's disease.</ArticleTitle>
<Pagination><MedlinePgn>288-9</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.26101</ELocationID>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Prundean</LastName>
<ForeName>Adriana</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Centre de référence des maladies neurogénétiques, Centre Hospitalier Universitaire, Angers, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Youssov</LastName>
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<Author ValidYN="Y"><LastName>Humbert</LastName>
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<Author ValidYN="Y"><LastName>Bonneau</LastName>
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<Author ValidYN="Y"><LastName>Verny</LastName>
<ForeName>Christophe</ForeName>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D017427">Clinical Trial, Phase II</PublicationType>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>5UX2SD1KE2</RegistryNumber>
<NameOfSubstance UI="D003543">Cysteamine</NameOfSubstance>
</Chemical>
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<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000293">Adolescent</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003543">Cysteamine</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000008">administration & dosage</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004361">Drug Tolerance</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006816">Huntington Disease</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
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</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D055815">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Huntington's disease</Keyword>
<Keyword MajorTopicYN="N">cysteamine</Keyword>
<Keyword MajorTopicYN="N">tolerability</Keyword>
</KeywordList>
</MedlineCitation>
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<PubMedPubDate PubStatus="revised"><Year>2014</Year>
<Month>9</Month>
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<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
<Month>10</Month>
<Day>27</Day>
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<PubMedPubDate PubStatus="aheadofprint"><Year>2014</Year>
<Month>12</Month>
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<PublicationStatus>ppublish</PublicationStatus>
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