Tics in a patient with Parkinson's disease.
Identifieur interne : 005100 ( PubMed/Checkpoint ); précédent : 005099; suivant : 005101Tics in a patient with Parkinson's disease.
Auteurs : H. Shale [États-Unis] ; S. Fahn ; R. MayeuxSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1986.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Levodopa.
- chemically induced : Tourette Syndrome.
- complications : Parkinson Disease, Tourette Syndrome.
- drug therapy : Parkinson Disease.
- chemical , physiology : Receptors, Dopamine.
- physiopathology : Tourette Syndrome.
- Humans, Male, Middle Aged.
Abstract
A patient with Gilles de la Tourette syndrome later developed Parkinson's disease in middle age. This was accompanied by a marked reduction in the frequency of tics but levodopa toxicity exacerbated the tics. The dopamine hypothesis of tic disorders is supported by this observation.
DOI: 10.1002/mds.870010111
PubMed: 3504234
Affiliations:
Links toward previous steps (curation, corpus...)
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pubmed:3504234Le document en format XML
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<front><div type="abstract" xml:lang="en">A patient with Gilles de la Tourette syndrome later developed Parkinson's disease in middle age. This was accompanied by a marked reduction in the frequency of tics but levodopa toxicity exacerbated the tics. The dopamine hypothesis of tic disorders is supported by this observation.</div>
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