MovDisordV3, PubMed, Checkpoint, bibRecord, 004A73

Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.

Identifieur interne : 004A73 ( PubMed/Checkpoint ); précédent : 004A72; suivant : 004A74

Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.

Auteurs : H. Reichmann [Allemagne] ; M. Naumann ; S. Hauck ; B. Janetzky

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1994.

RBID : pubmed:7845398

English descriptors

KwdEn :
- Adult, Aged, Blood Platelets (metabolism), Blotting, Southern, Chromosome Deletion, DNA, Mitochondrial (blood), DNA, Mitochondrial (genetics), Dystonia (genetics), Dystonia (physiopathology), Electron Transport (genetics), Electron Transport (physiology), Female, Humans, Male, Middle Aged, NAD(P)H Dehydrogenase (Quinone) (deficiency), Neurologic Examination, Torticollis (genetics), Torticollis (physiopathology).
MESH :
- chemical , blood : DNA, Mitochondrial.
- chemical , deficiency : NAD(P)H Dehydrogenase (Quinone).
- chemical , genetics : DNA, Mitochondrial.
- genetics : Dystonia, Electron Transport, Torticollis.
- metabolism : Blood Platelets.
- physiology : Electron Transport.
- physiopathology : Dystonia, Torticollis.
- Adult, Aged, Blotting, Southern, Chromosome Deletion, Female, Humans, Male, Middle Aged, Neurologic Examination.

Abstract

An increasing number of neurodegenerative diseases seem to be associated with or even due to disturbances of cerebral energy metabolism. One generally accepted example is complex I deficiency in substantia nigra from patients with Parkinson's disease. Reports on a complex I defect in platelets from patients with dystonia led us to check for disturbances of the respiratory chain or of the mitochondrial genome in isolated mitochondria from patients with focal or generalized dystonia. We could not confirm the idea of mitochondrial disturbance in platelets from patients with dystonia because we did not find abnormal enzyme activities or any deletions of the mitochondrial genome. Thus, we do not think that blood cells such as platelets can serve as markers for neurodegenerative disorders such as dystonia.

DOI: 10.1002/mds.870090603
PubMed: 7845398

Affiliations:

Allemagne

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 004A54
to stream PubMed, to step Curation: 004A54

Links to Exploration step

pubmed:7845398

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.</title>
<author><name sortKey="Reichmann, H" sort="Reichmann, H" uniqKey="Reichmann H" first="H" last="Reichmann">H. Reichmann</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Würzburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Würzburg</wicri:regionArea>
<wicri:noRegion>University of Würzburg</wicri:noRegion>
<wicri:noRegion>University of Würzburg</wicri:noRegion>
<wicri:noRegion>University of Würzburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Naumann, M" sort="Naumann, M" uniqKey="Naumann M" first="M" last="Naumann">M. Naumann</name>
</author>
<author><name sortKey="Hauck, S" sort="Hauck, S" uniqKey="Hauck S" first="S" last="Hauck">S. Hauck</name>
</author>
<author><name sortKey="Janetzky, B" sort="Janetzky, B" uniqKey="Janetzky B" first="B" last="Janetzky">B. Janetzky</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1994">1994</date>
<idno type="RBID">pubmed:7845398</idno>
<idno type="pmid">7845398</idno>
<idno type="doi">10.1002/mds.870090603</idno>
<idno type="wicri:Area/PubMed/Corpus">004A54</idno>
<idno type="wicri:Area/PubMed/Curation">004A54</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004A73</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.</title>
<author><name sortKey="Reichmann, H" sort="Reichmann, H" uniqKey="Reichmann H" first="H" last="Reichmann">H. Reichmann</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Würzburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Würzburg</wicri:regionArea>
<wicri:noRegion>University of Würzburg</wicri:noRegion>
<wicri:noRegion>University of Würzburg</wicri:noRegion>
<wicri:noRegion>University of Würzburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Naumann, M" sort="Naumann, M" uniqKey="Naumann M" first="M" last="Naumann">M. Naumann</name>
</author>
<author><name sortKey="Hauck, S" sort="Hauck, S" uniqKey="Hauck S" first="S" last="Hauck">S. Hauck</name>
</author>
<author><name sortKey="Janetzky, B" sort="Janetzky, B" uniqKey="Janetzky B" first="B" last="Janetzky">B. Janetzky</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="1994" type="published">1994</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Blood Platelets (metabolism)</term>
<term>Blotting, Southern</term>
<term>Chromosome Deletion</term>
<term>DNA, Mitochondrial (blood)</term>
<term>DNA, Mitochondrial (genetics)</term>
<term>Dystonia (genetics)</term>
<term>Dystonia (physiopathology)</term>
<term>Electron Transport (genetics)</term>
<term>Electron Transport (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>NAD(P)H Dehydrogenase (Quinone) (deficiency)</term>
<term>Neurologic Examination</term>
<term>Torticollis (genetics)</term>
<term>Torticollis (physiopathology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>DNA, Mitochondrial</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>NAD(P)H Dehydrogenase (Quinone)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>DNA, Mitochondrial</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Dystonia</term>
<term>Electron Transport</term>
<term>Torticollis</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Blood Platelets</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Electron Transport</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dystonia</term>
<term>Torticollis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Blotting, Southern</term>
<term>Chromosome Deletion</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neurologic Examination</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">An increasing number of neurodegenerative diseases seem to be associated with or even due to disturbances of cerebral energy metabolism. One generally accepted example is complex I deficiency in substantia nigra from patients with Parkinson's disease. Reports on a complex I defect in platelets from patients with dystonia led us to check for disturbances of the respiratory chain or of the mitochondrial genome in isolated mitochondria from patients with focal or generalized dystonia. We could not confirm the idea of mitochondrial disturbance in platelets from patients with dystonia because we did not find abnormal enzyme activities or any deletions of the mitochondrial genome. Thus, we do not think that blood cells such as platelets can serve as markers for neurodegenerative disorders such as dystonia.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">7845398</PMID>
<DateCreated><Year>1995</Year>
<Month>03</Month>
<Day>08</Day>
</DateCreated>
<DateCompleted><Year>1995</Year>
<Month>03</Month>
<Day>08</Day>
</DateCompleted>
<DateRevised><Year>2007</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN>
<JournalIssue CitedMedium="Print"><Volume>9</Volume>
<Issue>6</Issue>
<PubDate><Year>1994</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.</ArticleTitle>
<Pagination><MedlinePgn>597-600</MedlinePgn>
</Pagination>
<Abstract><AbstractText>An increasing number of neurodegenerative diseases seem to be associated with or even due to disturbances of cerebral energy metabolism. One generally accepted example is complex I deficiency in substantia nigra from patients with Parkinson's disease. Reports on a complex I defect in platelets from patients with dystonia led us to check for disturbances of the respiratory chain or of the mitochondrial genome in isolated mitochondria from patients with focal or generalized dystonia. We could not confirm the idea of mitochondrial disturbance in platelets from patients with dystonia because we did not find abnormal enzyme activities or any deletions of the mitochondrial genome. Thus, we do not think that blood cells such as platelets can serve as markers for neurodegenerative disorders such as dystonia.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Reichmann</LastName>
<ForeName>H</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, University of Würzburg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Naumann</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hauck</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Janetzky</LastName>
<ForeName>B</ForeName>
<Initials>B</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>UNITED STATES</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D004272">DNA, Mitochondrial</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 1.6.5.2</RegistryNumber>
<NameOfSubstance UI="D016660">NAD(P)H Dehydrogenase (Quinone)</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001792">Blood Platelets</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000378">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D015139">Blotting, Southern</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002872">Chromosome Deletion</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004272">DNA, Mitochondrial</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000097">blood</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004421">Dystonia</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004579">Electron Transport</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D016660">NAD(P)H Dehydrogenase (Quinone)</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000172">deficiency</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D009460">Neurologic Examination</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014103">Torticollis</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1994</Year>
<Month>11</Month>
<Day>1</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1994</Year>
<Month>11</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>1</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>1994</Year>
<Month>11</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">7845398</ArticleId>
<ArticleId IdType="doi">10.1002/mds.870090603</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Allemagne</li>
</country>
</list>
<tree><noCountry><name sortKey="Hauck, S" sort="Hauck, S" uniqKey="Hauck S" first="S" last="Hauck">S. Hauck</name>
<name sortKey="Janetzky, B" sort="Janetzky, B" uniqKey="Janetzky B" first="B" last="Janetzky">B. Janetzky</name>
<name sortKey="Naumann, M" sort="Naumann, M" uniqKey="Naumann M" first="M" last="Naumann">M. Naumann</name>
</noCountry>
<country name="Allemagne"><noRegion><name sortKey="Reichmann, H" sort="Reichmann, H" uniqKey="Reichmann H" first="H" last="Reichmann">H. Reichmann</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004A73 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 004A73 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:7845398
   |texte=   Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:7845398" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a MovDisordV3

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.

Respiratory chain and mitochondrial deoxyribonucleic acid in blood cells from patients with focal and generalized dystonia.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki