Movement Disorders (revue)

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Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst.

Identifieur interne : 004497 ( PubMed/Checkpoint ); précédent : 004496; suivant : 004498

Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst.

Auteurs : C. Singer [États-Unis] ; N J Schatz ; B. Bowen ; D. Eidelberg ; K. Kazumata ; L. Sternau ; L M Shulman ; W J Weiner

Source :

RBID : pubmed:9452338

English descriptors

Abstract

A 66-year-old woman presented with a 3-year history of predominantly right-sided blepharospasm and a 1-year history of progressive predominantly left-sided hemiparkinsonism manifested by a left upper extremity resting tremor and left-sided bradykinesia. Magnetic resonance imaging of the brain revealed a large right mesencephalic cyst with mass effect. Positron emission tomography revealed bilateral striatal hypometabolism consistent with nigrostriatal dopaminergic dysfunction. The association of predominantly ipsilateral blepharospasm and predominantly contralateral hemiparkinsonism is very rare, and its association with a posterior fossa space-occupying lesion has been reported only once. This is the second report of such an association and the first description of adult-onset symptomatology.

DOI: 10.1002/mds.870130125
PubMed: 9452338


Affiliations:


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pubmed:9452338

Le document en format XML

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<term>Arachnoid Cysts (physiopathology)</term>
<term>Arm</term>
<term>Blepharospasm (etiology)</term>
<term>Blepharospasm (pathology)</term>
<term>Blepharospasm (physiopathology)</term>
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<term>Magnetic Resonance Imaging</term>
<term>Mesencephalon (pathology)</term>
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<div type="abstract" xml:lang="en">A 66-year-old woman presented with a 3-year history of predominantly right-sided blepharospasm and a 1-year history of progressive predominantly left-sided hemiparkinsonism manifested by a left upper extremity resting tremor and left-sided bradykinesia. Magnetic resonance imaging of the brain revealed a large right mesencephalic cyst with mass effect. Positron emission tomography revealed bilateral striatal hypometabolism consistent with nigrostriatal dopaminergic dysfunction. The association of predominantly ipsilateral blepharospasm and predominantly contralateral hemiparkinsonism is very rare, and its association with a posterior fossa space-occupying lesion has been reported only once. This is the second report of such an association and the first description of adult-onset symptomatology.</div>
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