MovDisordV3, PubMed, Checkpoint, bibRecord, 002008

Ultrasound-guided injection of the iliopsoas muscle with botulinum toxin in camptocormia.

Identifieur interne : 002008 ( PubMed/Checkpoint ); précédent : 002007; suivant : 002009

Ultrasound-guided injection of the iliopsoas muscle with botulinum toxin in camptocormia.

Auteurs : Rainer Von Coelln [Allemagne] ; Armin Raible ; Thomas Gasser ; Friedrich Asmus

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.

RBID : pubmed:18307265

English descriptors

KwdEn :
- Aged, Anti-Dyskinesia Agents (therapeutic use), Botulinum Toxins (therapeutic use), Female, Humans, Male, Parkinson Disease (complications), Parkinson Disease (drug therapy), Psoas Muscles, Treatment Outcome.
MESH :
- chemical , therapeutic use : Anti-Dyskinesia Agents, Botulinum Toxins.
- complications : Parkinson Disease.
- drug therapy : Parkinson Disease.
- Aged, Female, Humans, Male, Psoas Muscles, Treatment Outcome.

Abstract

Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco-lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound-guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500-1,500 MU of BTX per side in 4-6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow-up visits, as well as self-assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism-associated camptocormia.

DOI: 10.1002/mds.21967
PubMed: 18307265

Affiliations:

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pubmed:18307265

Le document en format XML

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<author><name sortKey="Von Coelln, Rainer" sort="Von Coelln, Rainer" uniqKey="Von Coelln R" first="Rainer" last="Von Coelln">Rainer Von Coelln</name>
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<author><name sortKey="Gasser, Thomas" sort="Gasser, Thomas" uniqKey="Gasser T" first="Thomas" last="Gasser">Thomas Gasser</name>
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<author><name sortKey="Asmus, Friedrich" sort="Asmus, Friedrich" uniqKey="Asmus F" first="Friedrich" last="Asmus">Friedrich Asmus</name>
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<front><div type="abstract" xml:lang="en">Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco-lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound-guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500-1,500 MU of BTX per side in 4-6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow-up visits, as well as self-assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism-associated camptocormia.</div>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<Abstract><AbstractText>Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco-lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound-guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500-1,500 MU of BTX per side in 4-6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow-up visits, as well as self-assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism-associated camptocormia.</AbstractText>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Ultrasound-guided injection of the iliopsoas muscle with botulinum toxin in camptocormia.

Ultrasound-guided injection of the iliopsoas muscle with botulinum toxin in camptocormia.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

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