Primary lateral sclerosis as progressive supranuclear palsy: diagnosis by diffusion tensor imaging.
Identifieur interne : 000C75 ( PubMed/Checkpoint ); précédent : 000C74; suivant : 000C76Primary lateral sclerosis as progressive supranuclear palsy: diagnosis by diffusion tensor imaging.
Auteurs : Elizabeth A. Coon [États-Unis] ; Jennifer L. Whitwell ; Clifford R. Jack ; Keith A. JosephsSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2012.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Anisotropy, Case-Control Studies, Corpus Callosum (pathology), Diffusion Tensor Imaging, Female, Humans, Male, Middle Aged, Motor Neuron Disease (diagnosis), Prospective Studies, Pyramidal Tracts (pathology), Supranuclear Palsy, Progressive (physiopathology), Tegmentum Mesencephali (pathology).
- MESH :
- diagnosis : Motor Neuron Disease.
- pathology : Corpus Callosum, Pyramidal Tracts, Tegmentum Mesencephali.
- physiopathology : Supranuclear Palsy, Progressive.
- Aged, Aged, 80 and over, Anisotropy, Case-Control Studies, Diffusion Tensor Imaging, Female, Humans, Male, Middle Aged, Prospective Studies.
Abstract
Evaluating the integrity of white matter tracts with diffusion tensor imaging may differentiate primary lateral sclerosis from progressive supranuclear palsy.
DOI: 10.1002/mds.24990
PubMed: 22517038
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:22517038Le document en format XML
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Corpus Callosum (pathology)</term>
<term>Diffusion Tensor Imaging</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Motor Neuron Disease (diagnosis)</term>
<term>Prospective Studies</term>
<term>Pyramidal Tracts (pathology)</term>
<term>Supranuclear Palsy, Progressive (physiopathology)</term>
<term>Tegmentum Mesencephali (pathology)</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Motor Neuron Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Corpus Callosum</term>
<term>Pyramidal Tracts</term>
<term>Tegmentum Mesencephali</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Supranuclear Palsy, Progressive</term>
</keywords>
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<term>Aged, 80 and over</term>
<term>Anisotropy</term>
<term>Case-Control Studies</term>
<term>Diffusion Tensor Imaging</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">Evaluating the integrity of white matter tracts with diffusion tensor imaging may differentiate primary lateral sclerosis from progressive supranuclear palsy.</div>
</front>
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<Month>06</Month>
<Day>25</Day>
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<DateCompleted><Year>2012</Year>
<Month>11</Month>
<Day>13</Day>
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<Day>16</Day>
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<Issue>7</Issue>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>Primary lateral sclerosis as progressive supranuclear palsy: diagnosis by diffusion tensor imaging.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Evaluating the integrity of white matter tracts with diffusion tensor imaging may differentiate primary lateral sclerosis from progressive supranuclear palsy.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Thirty-three prospectively recruited subjects had standardized evaluations and diffusion tensor imaging: 3 with primary lateral sclerosis who presented with features suggestive of progressive supranuclear palsy, 10 with probable or definite progressive supranuclear palsy, and 20 matched controls. We compared fractional anisotropy of the corticospinal tract, superior cerebellar peduncles, and body of the corpus callosum between groups.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Both the primary lateral sclerosis and progressive supranuclear palsy subjects showed reduced fractional anisotropy in superior cerebellar peduncle and body of the corpus callosum compared with controls, but only primary lateral sclerosis subjects showed reductions in the corticospinal tracts. A ratio of corticospinal tract/superior cerebellar peduncle best distinguished the disorders (P < .02).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The corticospinal tract/superior cerebellar peduncle ratio is a marker to differentiate primary lateral sclerosis from progressive supranuclear palsy.</AbstractText>
<CopyrightInformation>Copyright © 2012 Movement Disorder Society.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Coon</LastName>
<ForeName>Elizabeth A</ForeName>
<Initials>EA</Initials>
<AffiliationInfo><Affiliation>Department of Neurology (Behavioral Neurology), Mayo Clinic, Rochester, Minnesota 55905, USA.</Affiliation>
</AffiliationInfo>
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<ForeName>Jennifer L</ForeName>
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<Language>eng</Language>
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