Deep brain stimulation for gait and postural symptoms in Parkinson's disease.
Identifieur interne : 000A45 ( PubMed/Checkpoint ); précédent : 000A44; suivant : 000A46Deep brain stimulation for gait and postural symptoms in Parkinson's disease.
Auteurs : Monika Pötter-Nerger [Allemagne] ; Jens VolkmannSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- complications : Parkinson Disease.
- etiology : Gait Disorders, Neurologic, Sensation Disorders.
- methods : Deep Brain Stimulation.
- physiology : Postural Balance.
- therapy : Gait Disorders, Neurologic, Sensation Disorders.
- Humans.
Abstract
In patients with Parkinson's disease, gait and balance difficulties have emerged as some of the main therapeutic concerns. During earlier stages of the disease, the dopamine-responsive aspects of gait disorder can be treated initially with dopaminergic drugs or deep brain stimulation. However, certain temporal aspects of parkinsonian gait disorder remain therapeutically resistant in both the short term and the long term. In this review, we summarize the effects of deep brain stimulation on gait and postural symptoms in the five currently available targets (subthalamic nucleus, globus pallidus, ventralis intermedius thalamic nucleus, pedunculopontine nucleus, and substantia nigra) and describe programming strategies for patients who are mainly disabled by gait problems.
DOI: 10.1002/mds.25677
PubMed: 24132849
Affiliations:
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In this review, we summarize the effects of deep brain stimulation on gait and postural symptoms in the five currently available targets (subthalamic nucleus, globus pallidus, ventralis intermedius thalamic nucleus, pedunculopontine nucleus, and substantia nigra) and describe programming strategies for patients who are mainly disabled by gait problems.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">24132849</PMID><DateCreated><Year>2013</Year><Month>10</Month><Day>17</Day></DateCreated><DateCompleted><Year>2014</Year><Month>05</Month><Day>19</Day></DateCompleted><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>28</Volume><Issue>11</Issue><PubDate><Year>2013</Year><Month>Sep</Month><Day>15</Day></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. 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