Treatment of proximal upper limb tremor with botulinum toxin therapy.
Identifieur interne : 000373 ( PubMed/Checkpoint ); précédent : 000372; suivant : 000374Treatment of proximal upper limb tremor with botulinum toxin therapy.
Auteurs : Samuel D. Kim [Australie] ; Con Yiannikas ; Neil Mahant ; Steve Vucic ; Victor S C. FungSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Botulinum Toxins, Neurotoxins.
- drug therapy : Tremor.
- physiopathology : Upper Extremity.
- Adult, Aged, Aged, 80 and over, Disability Evaluation, Female, Humans, Male, Middle Aged, Outcome Assessment (Health Care), Retrospective Studies, Young Adult.
Abstract
Proximal-dominant upper limb tremor is highly disabling, and there is no effective medical therapy. In this study, we evaluated the efficacy of botulinum toxin (BTX) injections for the treatment of proximal tremor.
DOI: 10.1002/mds.25739
PubMed: 24519658
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Treatment of proximal upper limb tremor with botulinum toxin therapy.</title><author><name sortKey="Kim, Samuel D" sort="Kim, Samuel D" uniqKey="Kim S" first="Samuel D" last="Kim">Samuel D. Kim</name><affiliation wicri:level="1"><nlm:affiliation>Movement Disorders Unit, Department of Neurology, Westmead Hospital, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Movement Disorders Unit, Department of Neurology, Westmead Hospital, Sydney, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Yiannikas, Con" sort="Yiannikas, Con" uniqKey="Yiannikas C" first="Con" last="Yiannikas">Con Yiannikas</name></author><author><name sortKey="Mahant, Neil" sort="Mahant, Neil" uniqKey="Mahant N" first="Neil" last="Mahant">Neil Mahant</name></author><author><name sortKey="Vucic, Steve" sort="Vucic, Steve" uniqKey="Vucic S" first="Steve" last="Vucic">Steve Vucic</name></author><author><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S C" last="Fung">Victor S C. Fung</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24519658</idno><idno type="pmid">24519658</idno><idno type="doi">10.1002/mds.25739</idno><idno type="wicri:Area/PubMed/Corpus">000582</idno><idno type="wicri:Area/PubMed/Curation">000582</idno><idno type="wicri:Area/PubMed/Checkpoint">000373</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Treatment of proximal upper limb tremor with botulinum toxin therapy.</title><author><name sortKey="Kim, Samuel D" sort="Kim, Samuel D" uniqKey="Kim S" first="Samuel D" last="Kim">Samuel D. Kim</name><affiliation wicri:level="1"><nlm:affiliation>Movement Disorders Unit, Department of Neurology, Westmead Hospital, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Movement Disorders Unit, Department of Neurology, Westmead Hospital, Sydney, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Yiannikas, Con" sort="Yiannikas, Con" uniqKey="Yiannikas C" first="Con" last="Yiannikas">Con Yiannikas</name></author><author><name sortKey="Mahant, Neil" sort="Mahant, Neil" uniqKey="Mahant N" first="Neil" last="Mahant">Neil Mahant</name></author><author><name sortKey="Vucic, Steve" sort="Vucic, Steve" uniqKey="Vucic S" first="Steve" last="Vucic">Steve Vucic</name></author><author><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S C" last="Fung">Victor S C. Fung</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Botulinum Toxins (therapeutic use)</term><term>Disability Evaluation</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neurotoxins (therapeutic use)</term><term>Outcome Assessment (Health Care)</term><term>Retrospective Studies</term><term>Tremor (drug therapy)</term><term>Upper Extremity (physiopathology)</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Botulinum Toxins</term><term>Neurotoxins</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Tremor</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Upper Extremity</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Disability Evaluation</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Outcome Assessment (Health Care)</term><term>Retrospective Studies</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Proximal-dominant upper limb tremor is highly disabling, and there is no effective medical therapy. In this study, we evaluated the efficacy of botulinum toxin (BTX) injections for the treatment of proximal tremor.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">24519658</PMID><DateCreated><Year>2014</Year><Month>05</Month><Day>06</Day></DateCreated><DateCompleted><Year>2014</Year><Month>12</Month><Day>19</Day></DateCompleted><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>29</Volume><Issue>6</Issue><PubDate><Year>2014</Year><Month>May</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Treatment of proximal upper limb tremor with botulinum toxin therapy.</ArticleTitle><Pagination><MedlinePgn>835-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.25739</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Proximal-dominant upper limb tremor is highly disabling, and there is no effective medical therapy. In this study, we evaluated the efficacy of botulinum toxin (BTX) injections for the treatment of proximal tremor.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We conducted a retrospective analysis of open-label treatment with BTX in 19 patients with proximal tremor. The response to therapy was graded into four categories according to self-reported improvements in tremor and function.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In total, 63% of patients reported moderate or marked benefit, defined as functional improvements sufficient enough to allow feeding or drinking from a cup; whereas 21% of patients reported mild benefit; and 15% of patients reported no benefit. One patient developed severe weakness of shoulder abduction and withdrew from the treatment; otherwise, the therapy was free of side effects.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The current findings support the efficacy of BTX therapy in the treatment of proximal upper limb tremor with minimal side effects.</AbstractText><CopyrightInformation>© 2013 International Parkinson and Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Samuel D</ForeName><Initials>SD</Initials><AffiliationInfo><Affiliation>Movement Disorders Unit, Department of Neurology, Westmead Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yiannikas</LastName><ForeName>Con</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Mahant</LastName><ForeName>Neil</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Vucic</LastName><ForeName>Steve</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Fung</LastName><ForeName>Victor S C</ForeName><Initials>VS</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>11</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009498">Neurotoxins</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.24.69</RegistryNumber><NameOfSubstance UI="D001905">Botulinum Toxins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001905">Botulinum Toxins</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004185">Disability Evaluation</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009498">Neurotoxins</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017063">Outcome Assessment (Health Care)</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012189">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014202">Tremor</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000188">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D034941">Upper Extremity</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D055815">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">botulinum toxin</Keyword><Keyword MajorTopicYN="N">proximal tremor</Keyword><Keyword MajorTopicYN="N">wing-beating tremor</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>6</Month><Day>5</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2013</Year><Month>8</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>9</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2013</Year><Month>11</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>12</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24519658</ArticleId><ArticleId IdType="doi">10.1002/mds.25739</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li></country></list><tree><noCountry><name sortKey="Fung, Victor S C" sort="Fung, Victor S C" uniqKey="Fung V" first="Victor S C" last="Fung">Victor S C. Fung</name><name sortKey="Mahant, Neil" sort="Mahant, Neil" uniqKey="Mahant N" first="Neil" last="Mahant">Neil Mahant</name><name sortKey="Vucic, Steve" sort="Vucic, Steve" uniqKey="Vucic S" first="Steve" last="Vucic">Steve Vucic</name><name sortKey="Yiannikas, Con" sort="Yiannikas, Con" uniqKey="Yiannikas C" first="Con" last="Yiannikas">Con Yiannikas</name></noCountry><country name="Australie"><noRegion><name sortKey="Kim, Samuel D" sort="Kim, Samuel D" uniqKey="Kim S" first="Samuel D" last="Kim">Samuel D. Kim</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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