Global cognitive scores do not predict outcome after subthalamic nucleus deep brain stimulation.
Identifieur interne : 000224 ( PubMed/Checkpoint ); précédent : 000223; suivant : 000225Global cognitive scores do not predict outcome after subthalamic nucleus deep brain stimulation.
Auteurs : Darlene Floden [États-Unis] ; Robyn M. Busch [États-Unis] ; Scott E. Cooper [États-Unis] ; Cynthia S. Kubu [États-Unis] ; Andre G. Machado [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
Presence of dementia is a contraindication for DBS treatment of Parkinson's disease. Recent evidence suggests that borderline cognitive function, as measured with a common screening measure, the Mattis Dementia Rating Scale, has a negative impact on quality of life (QoL) after DBS of the STN.
DOI: 10.1002/mds.26292
PubMed: 26175227
Affiliations:
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<front><div type="abstract" xml:lang="en">Presence of dementia is a contraindication for DBS treatment of Parkinson's disease. Recent evidence suggests that borderline cognitive function, as measured with a common screening measure, the Mattis Dementia Rating Scale, has a negative impact on quality of life (QoL) after DBS of the STN.</div>
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<ArticleTitle>Global cognitive scores do not predict outcome after subthalamic nucleus deep brain stimulation.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Presence of dementia is a contraindication for DBS treatment of Parkinson's disease. Recent evidence suggests that borderline cognitive function, as measured with a common screening measure, the Mattis Dementia Rating Scale, has a negative impact on quality of life (QoL) after DBS of the STN.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We attempted to replicate and extend this finding in a larger group of patients with a wider range of preoperative global cognitive performance.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Our data indicate that performance on the screening measure is not associated with QoL or medical outcomes, even with scores well below the cutoff for identifying dementia.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This cognitive screening measure lacks sufficient sensitivity to warrant its use in predicting which patients will show QoL benefit from DBS.</AbstractText>
<CopyrightInformation>© 2015 International Parkinson and Movement Disorder Society.</CopyrightInformation>
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