Alcohol and Risk of Parkinson Disease in a Large Prospective Cohort of Men and Women
Identifieur interne : 000272 ( Pmc/Curation ); précédent : 000271; suivant : 000273Alcohol and Risk of Parkinson Disease in a Large Prospective Cohort of Men and Women
Auteurs : N. Palacios [États-Unis] ; X. Gao [États-Unis] ; E. O Eilly [États-Unis] ; M. Schwarzschild ; M. L. Mccullough [États-Unis] ; T. Mayo [États-Unis] ; S. M. Gapstur [États-Unis] ; A. Ascherio [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2012.
Abstract
Addictive behaviors such as cigarette smoking and coffee drinking have been associated with a reduced risk of Parkinson disease. Whether alcohol consumption is also associated with risk is less certain.
We prospectively followed 132,403 participants in the Cancer Prevention Study II Nutrition Cohort from 1992 to 2005. Alcohol intake was assessed at baseline. Incident cases of Parkinson Disease (n = 605; 389 male and 216 female) were confirmed by treating physicians and medical record review. Relative risks were estimated using proportional hazards models, adjusting for age, smoking and other risk factors.
Alcohol consumption was not significantly associated with Parkinson Disease risk. After adjustment for age, smoking, and other risk factors, the Relative Risk comparing men consuming 30 or more grams of alcohol (highest category) to non-drinker men was 1.29 (95% CI: 0.90, 1.86,
The results of this large prospective study do not support an association between alcohol intake and risk of Parkinson disease.
Url:
DOI: 10.1002/mds.25050
PubMed: 22714720
PubMed Central: 3548327
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000272
Links to Exploration step
PMC:3548327Curation
No country items
M. Schwarzschild<affiliation><nlm:aff id="A2">Massachusetts General Hospital, Boston, MA, 02114</nlm:aff><wicri:noCountry code="subfield">02114</wicri:noCountry></affiliation>Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Alcohol and Risk of Parkinson Disease in a Large Prospective Cohort of Men and Women</title><author><name sortKey="Palacios, N" sort="Palacios, N" uniqKey="Palacios N" first="N." last="Palacios">N. Palacios</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation></author><author><name sortKey="Gao, X" sort="Gao, X" uniqKey="Gao X" first="X." last="Gao">X. Gao</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="O Eilly, E" sort="O Eilly, E" uniqKey="O Eilly E" first="E." last="O Eilly">E. O Eilly</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation></author><author><name sortKey="Schwarzschild, M" sort="Schwarzschild, M" uniqKey="Schwarzschild M" first="M." last="Schwarzschild">M. Schwarzschild</name><affiliation><nlm:aff id="A2">Massachusetts General Hospital, Boston, MA, 02114</nlm:aff><wicri:noCountry code="subfield">02114</wicri:noCountry></affiliation></author><author><name sortKey="Mccullough, M L" sort="Mccullough, M L" uniqKey="Mccullough M" first="M. L." last="Mccullough">M. L. Mccullough</name><affiliation wicri:level="2"><nlm:aff id="A3">Epidemiology Research Program, 250 Williams St., Atlanta, GA 30303-1002</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Epidemiology Research Program, 250 Williams St., Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Mayo, T" sort="Mayo, T" uniqKey="Mayo T" first="T." last="Mayo">T. Mayo</name><affiliation wicri:level="2"><nlm:aff id="A3">Epidemiology Research Program, 250 Williams St., Atlanta, GA 30303-1002</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Epidemiology Research Program, 250 Williams St., Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Gapstur, S M" sort="Gapstur, S M" uniqKey="Gapstur S" first="S. M." last="Gapstur">S. M. Gapstur</name><affiliation wicri:level="2"><nlm:aff id="A3">Epidemiology Research Program, 250 Williams St., Atlanta, GA 30303-1002</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Epidemiology Research Program, 250 Williams St., Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Ascherio, A" sort="Ascherio, A" uniqKey="Ascherio A" first="A." last="Ascherio">A. Ascherio</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4">Dept. of Epidemiology, Harvard School of Public Health 677 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Epidemiology, Harvard School of Public Health 677 Huntington Ave., Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22714720</idno><idno type="pmc">3548327</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548327</idno><idno type="RBID">PMC:3548327</idno><idno type="doi">10.1002/mds.25050</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000272</idno><idno type="wicri:Area/Pmc/Curation">000272</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Alcohol and Risk of Parkinson Disease in a Large Prospective Cohort of Men and Women</title><author><name sortKey="Palacios, N" sort="Palacios, N" uniqKey="Palacios N" first="N." last="Palacios">N. Palacios</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation></author><author><name sortKey="Gao, X" sort="Gao, X" uniqKey="Gao X" first="X." last="Gao">X. Gao</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="O Eilly, E" sort="O Eilly, E" uniqKey="O Eilly E" first="E." last="O Eilly">E. O Eilly</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation></author><author><name sortKey="Schwarzschild, M" sort="Schwarzschild, M" uniqKey="Schwarzschild M" first="M." last="Schwarzschild">M. Schwarzschild</name><affiliation><nlm:aff id="A2">Massachusetts General Hospital, Boston, MA, 02114</nlm:aff><wicri:noCountry code="subfield">02114</wicri:noCountry></affiliation></author><author><name sortKey="Mccullough, M L" sort="Mccullough, M L" uniqKey="Mccullough M" first="M. L." last="Mccullough">M. L. Mccullough</name><affiliation wicri:level="2"><nlm:aff id="A3">Epidemiology Research Program, 250 Williams St., Atlanta, GA 30303-1002</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Epidemiology Research Program, 250 Williams St., Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Mayo, T" sort="Mayo, T" uniqKey="Mayo T" first="T." last="Mayo">T. Mayo</name><affiliation wicri:level="2"><nlm:aff id="A3">Epidemiology Research Program, 250 Williams St., Atlanta, GA 30303-1002</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Epidemiology Research Program, 250 Williams St., Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Gapstur, S M" sort="Gapstur, S M" uniqKey="Gapstur S" first="S. M." last="Gapstur">S. M. Gapstur</name><affiliation wicri:level="2"><nlm:aff id="A3">Epidemiology Research Program, 250 Williams St., Atlanta, GA 30303-1002</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Epidemiology Research Program, 250 Williams St., Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Ascherio, A" sort="Ascherio, A" uniqKey="Ascherio A" first="A." last="Ascherio">A. Ascherio</name><affiliation wicri:level="2"><nlm:aff id="A1">Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4">Dept. of Epidemiology, Harvard School of Public Health 677 Huntington Ave., Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dept. of Epidemiology, Harvard School of Public Health 677 Huntington Ave., Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA 02115</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston</wicri:cityArea></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title><p id="P1">Addictive behaviors such as cigarette smoking and coffee drinking have been associated with a reduced risk of Parkinson disease. Whether alcohol consumption is also associated with risk is less certain.</p></sec><sec id="S2"><title>Methods</title><p id="P2">We prospectively followed 132,403 participants in the Cancer Prevention Study II Nutrition Cohort from 1992 to 2005. Alcohol intake was assessed at baseline. Incident cases of Parkinson Disease (n = 605; 389 male and 216 female) were confirmed by treating physicians and medical record review. Relative risks were estimated using proportional hazards models, adjusting for age, smoking and other risk factors.</p></sec><sec id="S3"><title>Results</title><p id="P3">Alcohol consumption was not significantly associated with Parkinson Disease risk. After adjustment for age, smoking, and other risk factors, the Relative Risk comparing men consuming 30 or more grams of alcohol (highest category) to non-drinker men was 1.29 (95% CI: 0.90, 1.86, <italic>p-trend</italic>: 0.40) and the Relative Risk comparing women consuming 15 or more grams of alcohol (highest category) per day to non-drinker women was 0.77 (95% CI: 0.41, 1.45, <italic>p-trend</italic>: 0.87). Consumption of beer, wine or liquor was also not associated with Parkinson Disease risk.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">The results of this large prospective study do not support an association between alcohol intake and risk of Parkinson disease.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8610688</journal-id><journal-id journal-id-type="pubmed-jr-id">5937</journal-id><journal-id journal-id-type="nlm-ta">Mov Disord</journal-id><journal-id journal-id-type="iso-abbrev">Mov. Disord.</journal-id><journal-title-group><journal-title>Movement disorders : official journal of the Movement Disorder Society</journal-title></journal-title-group><issn pub-type="ppub">0885-3185</issn><issn pub-type="epub">1531-8257</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22714720</article-id><article-id pub-id-type="pmc">3548327</article-id><article-id pub-id-type="doi">10.1002/mds.25050</article-id><article-id pub-id-type="manuscript">NIHMS419260</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Alcohol and Risk of Parkinson Disease in a Large Prospective Cohort of Men and Women</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Palacios</surname><given-names>N.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Gao</surname><given-names>X.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>O’Reilly</surname><given-names>E.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Schwarzschild</surname><given-names>M.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>McCullough</surname><given-names>M.L.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Mayo</surname><given-names>T.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Gapstur</surname><given-names>S.M.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Ascherio</surname><given-names>A.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A5">5</xref></contrib></contrib-group><aff id="A1"><label>1</label>Dept. of Nutrition, Harvard School of Public Health 655 Huntington Ave., Boston, MA 02115</aff><aff id="A2"><label>2</label>Massachusetts General Hospital, Boston, MA, 02114</aff><aff id="A3"><label>3</label>Epidemiology Research Program, 250 Williams St., Atlanta, GA 30303-1002</aff><aff id="A4"><label>4</label>Dept. of Epidemiology, Harvard School of Public Health 677 Huntington Ave., Boston, MA 02115</aff><aff id="A5"><label>5</label>Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA 02115</aff><pub-date pub-type="nihms-submitted"><day>21</day><month>12</month><year>2012</year></pub-date><pub-date pub-type="epub"><day>19</day><month>6</month><year>2012</year></pub-date><pub-date pub-type="ppub"><month>7</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>7</month><year>2013</year></pub-date><volume>27</volume><issue>8</issue><fpage>980</fpage><lpage>987</lpage><abstract><sec id="S1"><title>Background</title><p id="P1">Addictive behaviors such as cigarette smoking and coffee drinking have been associated with a reduced risk of Parkinson disease. Whether alcohol consumption is also associated with risk is less certain.</p></sec><sec id="S2"><title>Methods</title><p id="P2">We prospectively followed 132,403 participants in the Cancer Prevention Study II Nutrition Cohort from 1992 to 2005. Alcohol intake was assessed at baseline. Incident cases of Parkinson Disease (n = 605; 389 male and 216 female) were confirmed by treating physicians and medical record review. Relative risks were estimated using proportional hazards models, adjusting for age, smoking and other risk factors.</p></sec><sec id="S3"><title>Results</title><p id="P3">Alcohol consumption was not significantly associated with Parkinson Disease risk. After adjustment for age, smoking, and other risk factors, the Relative Risk comparing men consuming 30 or more grams of alcohol (highest category) to non-drinker men was 1.29 (95% CI: 0.90, 1.86, <italic>p-trend</italic>: 0.40) and the Relative Risk comparing women consuming 15 or more grams of alcohol (highest category) per day to non-drinker women was 0.77 (95% CI: 0.41, 1.45, <italic>p-trend</italic>: 0.87). Consumption of beer, wine or liquor was also not associated with Parkinson Disease risk.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">The results of this large prospective study do not support an association between alcohol intake and risk of Parkinson disease.</p></sec></abstract><funding-group><award-group><funding-source country="United States">National Institute of Neurological Disorders and Stroke : NINDS</funding-source><award-id>R01 NS061858 || NS</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000272 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 000272 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Pmc
|étape= Curation
|type= RBID
|clé= PMC:3548327
|texte= Alcohol and Risk of Parkinson Disease in a Large Prospective Cohort of Men and Women
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:22714720" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |