Functional Correlates of Lower Cognitive Test Scores in Essential Tremor
Identifieur interne : 000344 ( Pmc/Checkpoint ); précédent : 000343; suivant : 000345Functional Correlates of Lower Cognitive Test Scores in Essential Tremor
Auteurs : Elan D. Louis [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2010.
Abstract
Although motor features have been the defining element of essential tremor (ET), lower neurocognitive test scores are increasingly being recognized. However, the clinical correlates, if any, of these lower test scores remain largely unexplored.
To determine whether cognitive test scores in ET have any functional correlates.
The Modified Mini Mental Status Examination (MMSE), Katz Activities of Daily Living (ADL) scale and Lawton Instrumental (I) ADL scale were administered to 95 cases.
The Katz ADL score (rho = 0.26, p = 0.01) and Lawton IADL score (rho = 0.32, p = 0.001) were correlated with MMSE scores, such that poorer cognitive performance indicated greater dysfunction. Furthermore, cognitive test scores were a better predictor of functional disability than was tremor severity.
Poorer cognitive performance in ET was associated with greater functional deficit. Cognition should enter the clinical dialogue with ET patients as an issue of clinical significance.
Url:
DOI: 10.1002/mds.22920
PubMed: 20108374
PubMed Central: 2847294
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:2847294Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Functional Correlates of Lower Cognitive Test Scores in Essential Tremor</title><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name><affiliation wicri:level="4"><nlm:aff id="A1">GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A3">Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A4">Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">20108374</idno><idno type="pmc">2847294</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847294</idno><idno type="RBID">PMC:2847294</idno><idno type="doi">10.1002/mds.22920</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">000081</idno><idno type="wicri:Area/Pmc/Curation">000081</idno><idno type="wicri:Area/Pmc/Checkpoint">000344</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Functional Correlates of Lower Cognitive Test Scores in Essential Tremor</title><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name><affiliation wicri:level="4"><nlm:aff id="A1">GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A3">Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A4">Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title><p id="P1">Although motor features have been the defining element of essential tremor (ET), lower neurocognitive test scores are increasingly being recognized. However, the clinical correlates, if any, of these lower test scores remain largely unexplored.</p></sec><sec id="S2"><title>Objective</title><p id="P2">To determine whether cognitive test scores in ET have any functional correlates.</p></sec><sec sec-type="methods" id="S3"><title>Methods</title><p id="P3">The Modified Mini Mental Status Examination (MMSE), Katz Activities of Daily Living (ADL) scale and Lawton Instrumental (I) ADL scale were administered to 95 cases.</p></sec><sec id="S4"><title>Results</title><p id="P4">The Katz ADL score (rho = 0.26, p = 0.01) and Lawton IADL score (rho = 0.32, p = 0.001) were correlated with MMSE scores, such that poorer cognitive performance indicated greater dysfunction. Furthermore, cognitive test scores were a better predictor of functional disability than was tremor severity.</p></sec><sec id="S5"><title>Conclusions</title><p id="P5">Poorer cognitive performance in ET was associated with greater functional deficit. Cognition should enter the clinical dialogue with ET patients as an issue of clinical significance.</p></sec></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8610688</journal-id><journal-id journal-id-type="pubmed-jr-id">5937</journal-id><journal-id journal-id-type="nlm-ta">Mov Disord</journal-id><journal-title>Movement disorders : official journal of the Movement Disorder Society</journal-title><issn pub-type="ppub">0885-3185</issn><issn pub-type="epub">1531-8257</issn></journal-meta><article-meta><article-id pub-id-type="pmid">20108374</article-id><article-id pub-id-type="pmc">2847294</article-id><article-id pub-id-type="doi">10.1002/mds.22920</article-id><article-id pub-id-type="manuscript">NIHMS183788</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Functional Correlates of Lower Cognitive Test Scores in Essential Tremor</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Louis</surname><given-names>Elan D.</given-names></name><degrees>M.D., M.Sc.</degrees><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A3">3</xref><xref ref-type="aff" rid="A4">4</xref></contrib></contrib-group><aff id="A1"><label>1</label>GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA</aff><aff id="A2"><label>2</label>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA</aff><aff id="A3"><label>3</label>Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA</aff><aff id="A4"><label>4</label>Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA</aff><author-notes><corresp id="cor1">Correspondence: Dr. Elan Louis, Unit 198, Neurological Institute, 710 West 168th Street, New York, NY, 10032, USA. Tel: (212) 305 - 9194, FAX: (212) 305 -1304, <email>EDL2@columbia.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>16</day><month>3</month><year>2010</year></pub-date><pub-date pub-type="ppub"><day>15</day><month>3</month><year>2010</year></pub-date><pub-date pub-type="pmc-release"><day>30</day><month>3</month><year>2010</year></pub-date><volume>25</volume><issue>4</issue><fpage>481</fpage><lpage>485</lpage><abstract><sec id="S1"><title>Background</title><p id="P1">Although motor features have been the defining element of essential tremor (ET), lower neurocognitive test scores are increasingly being recognized. However, the clinical correlates, if any, of these lower test scores remain largely unexplored.</p></sec><sec id="S2"><title>Objective</title><p id="P2">To determine whether cognitive test scores in ET have any functional correlates.</p></sec><sec sec-type="methods" id="S3"><title>Methods</title><p id="P3">The Modified Mini Mental Status Examination (MMSE), Katz Activities of Daily Living (ADL) scale and Lawton Instrumental (I) ADL scale were administered to 95 cases.</p></sec><sec id="S4"><title>Results</title><p id="P4">The Katz ADL score (rho = 0.26, p = 0.01) and Lawton IADL score (rho = 0.32, p = 0.001) were correlated with MMSE scores, such that poorer cognitive performance indicated greater dysfunction. Furthermore, cognitive test scores were a better predictor of functional disability than was tremor severity.</p></sec><sec id="S5"><title>Conclusions</title><p id="P5">Poorer cognitive performance in ET was associated with greater functional deficit. Cognition should enter the clinical dialogue with ET patients as an issue of clinical significance.</p></sec></abstract><kwd-group><kwd>essential tremor</kwd><kwd>cognition</kwd><kwd>dementia</kwd><kwd>mini mental status</kwd><kwd>functional disability</kwd><kwd>epidemiology</kwd><kwd>Alzheimer’s disease</kwd></kwd-group><contract-num rid="NS1">R01 NS039422-09
||NS</contract-num><contract-num rid="NS1">R01 NS039422-08
||NS</contract-num><contract-num rid="NS1">R01 NS039422-06
||NS</contract-num><contract-sponsor id="NS1">National Institute of Neurological Disorders and Stroke : NINDS</contract-sponsor></article-meta></front></pmc><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region><settlement><li>New York</li></settlement><orgName><li>Université Columbia</li></orgName></list><tree><country name="États-Unis"><region name="État de New York"><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name></region><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000344 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000344 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:2847294
|texte= Functional Correlates of Lower Cognitive Test Scores in Essential Tremor
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:20108374" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |