Movement Disorders (revue)

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Weak Detrusor Contractility Correlates With Motor Disorders in Parkinson's Disease

Identifieur interne : 002C93 ( PascalFrancis/Curation ); précédent : 002C92; suivant : 002C94

Weak Detrusor Contractility Correlates With Motor Disorders in Parkinson's Disease

Auteurs : Keiichiro Terayama [Japon] ; Ryuji Sakakibara [Japon] ; Akihiro Ogawa [Japon] ; Hiroyuki Haruta [Japon] ; Takashi Akiba [Japon] ; Takeki Nagao [Japon] ; Osamu Takahashi [Japon] ; Megumi Sugiyama [Japon] ; Akihiko Tateno [Japon] ; Fuyuki Tateno [Japon] ; Masashi Yano [Japon] ; Masahiko Kishi [Japon] ; Yohei Tsuyusaki [Japon] ; Tomoyuki Uchiyama [Japon] ; Tatsuya Yamamoto [Japon]

Source :

RBID : Pascal:13-0063581

Descripteurs français

English descriptors

Abstract

Limited attention has been paid to the relationship between urinary symptoms or urodynamic findings and motor disorders in Parkinson's disease (PD). We aimed to correlate pressure-flow urodynamic parameters with video-gait analysis parameters in PD. We recruited 41 patients with PD (25 men and 16 women; age, 70.6 ± 8.5 years; H & Y motor grading: 2 [range, 1-3]; disease duration: 4 years [range, 1-7]; taking levodopa 300 mg/day [range, 100-400]). All patients underwent pressure-flow urodynamics (parameters: first sensation, bladder capacity, detrusor overactivity [noted in 24 patients], and Watts factor [WF]) and video-gait analysis (parameters: time and number of strides for 5-m gait [simple task] and time for timed up and go [complex task]). Statistical analysis was made by Mann-Whitney's U-test for analyzing the relation between detrusor over-activity and gait as well as Spearman's rank-correlation coefficient test for analyzing the relation between the remaining parameters and gait. We found no relation between filling-phase urodynamics (detrusor overactivity, first sensation, and bladder capacity) and video-gait analysis parameters. By contrast, we found a significant relation between voiding-phase urodynamics (WF, reflecting detrusor power) and all three video-gait analysis parameters (reflecting lower-half bradykinesia and loss of postural reflex) in our PD patients (P < 0.01). The close relation between the WF and motor disorders in the present study suggests that, though clinically mild, a weak detrusor in PD might have a central origin. We should follow postvoid residual volume carefully in PD patients with advanced gait disorder, because postvoid residual volume might increase in such patients. (.
pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 27
A06       @2 14
A08 01  1  ENG  @1 Weak Detrusor Contractility Correlates With Motor Disorders in Parkinson's Disease
A11 01  1    @1 TERAYAMA (Keiichiro)
A11 02  1    @1 SAKAKIBARA (Ryuji)
A11 03  1    @1 OGAWA (Akihiro)
A11 04  1    @1 HARUTA (Hiroyuki)
A11 05  1    @1 AKIBA (Takashi)
A11 06  1    @1 NAGAO (Takeki)
A11 07  1    @1 TAKAHASHI (Osamu)
A11 08  1    @1 SUGIYAMA (Megumi)
A11 09  1    @1 TATENO (Akihiko)
A11 10  1    @1 TATENO (Fuyuki)
A11 11  1    @1 YANO (Masashi)
A11 12  1    @1 KISHI (Masahiko)
A11 13  1    @1 TSUYUSAKI (Yohei)
A11 14  1    @1 UCHIYAMA (Tomoyuki)
A11 15  1    @1 YAMAMOTO (Tatsuya)
A14 01      @1 Rehabilitation Unit, Sakura Medical Center, Toho University @2 Sakura @3 JPN @Z 1 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
A14 02      @1 Neurology, Internal Medicine, Sakura Medical Center, Toho University @2 Sakura @3 JPN @Z 2 aut. @Z 9 aut. @Z 10 aut. @Z 12 aut. @Z 13 aut.
A14 03      @1 Neurosurgery, Sakura Medical Center, Toho University @2 Sakura @3 JPN @Z 6 aut.
A14 04      @1 Clinical Physiology Unit, Sakura Medical Center, Toho University @2 Sakura @3 JPN @Z 7 aut. @Z 8 aut.
A14 05      @1 Urology, Sakura Medical Center, Toho University @2 Sakura @3 JPN @Z 11 aut.
A14 06      @1 Neurology, Chiba University @2 Chiba @3 JPN @Z 14 aut. @Z 15 aut.
A20       @1 1775-1780
A21       @1 2012
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000503000040150
A44       @0 0000 @1 © 2013 INIST-CNRS. All rights reserved.
A45       @0 39 ref.
A47 01  1    @0 13-0063581
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 Limited attention has been paid to the relationship between urinary symptoms or urodynamic findings and motor disorders in Parkinson's disease (PD). We aimed to correlate pressure-flow urodynamic parameters with video-gait analysis parameters in PD. We recruited 41 patients with PD (25 men and 16 women; age, 70.6 ± 8.5 years; H & Y motor grading: 2 [range, 1-3]; disease duration: 4 years [range, 1-7]; taking levodopa 300 mg/day [range, 100-400]). All patients underwent pressure-flow urodynamics (parameters: first sensation, bladder capacity, detrusor overactivity [noted in 24 patients], and Watts factor [WF]) and video-gait analysis (parameters: time and number of strides for 5-m gait [simple task] and time for timed up and go [complex task]). Statistical analysis was made by Mann-Whitney's U-test for analyzing the relation between detrusor over-activity and gait as well as Spearman's rank-correlation coefficient test for analyzing the relation between the remaining parameters and gait. We found no relation between filling-phase urodynamics (detrusor overactivity, first sensation, and bladder capacity) and video-gait analysis parameters. By contrast, we found a significant relation between voiding-phase urodynamics (WF, reflecting detrusor power) and all three video-gait analysis parameters (reflecting lower-half bradykinesia and loss of postural reflex) in our PD patients (P < 0.01). The close relation between the WF and motor disorders in the present study suggests that, though clinically mild, a weak detrusor in PD might have a central origin. We should follow postvoid residual volume carefully in PD patients with advanced gait disorder, because postvoid residual volume might increase in such patients. (.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Trouble moteur @5 01
C03 01  X  ENG  @0 Motor system disorder @5 01
C03 01  X  SPA  @0 Trastorno motor @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
C03 02  X  ENG  @0 Parkinson disease @2 NM @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
C03 03  X  FRE  @0 Vessie hyperactive @2 NM @5 03
C03 03  X  ENG  @0 Overactive bladder @2 NM @5 03
C03 03  X  SPA  @0 Vejiga hiperactiva @2 NM @5 03
C03 04  X  FRE  @0 Pathologie du système nerveux @5 04
C03 04  X  ENG  @0 Nervous system diseases @5 04
C03 04  X  SPA  @0 Sistema nervioso patología @5 04
C03 05  X  FRE  @0 Contractilité @5 09
C03 05  X  ENG  @0 Contractility @5 09
C03 05  X  SPA  @0 Contractilidad @5 09
C03 06  X  FRE  @0 Vessie urinaire @5 10
C03 06  X  ENG  @0 Urinary bladder @5 10
C03 06  X  SPA  @0 Vejiga @5 10
C07 01  X  FRE  @0 Trouble neurologique @5 38
C07 01  X  ENG  @0 Neurological disorder @5 38
C07 01  X  SPA  @0 Trastorno neurológico @5 38
C07 02  X  FRE  @0 Pathologie de l'encéphale @5 39
C07 02  X  ENG  @0 Cerebral disorder @5 39
C07 02  X  SPA  @0 Encéfalo patología @5 39
C07 03  X  FRE  @0 Syndrome extrapyramidal @5 40
C07 03  X  ENG  @0 Extrapyramidal syndrome @5 40
C07 03  X  SPA  @0 Extrapiramidal síndrome @5 40
C07 04  X  FRE  @0 Maladie dégénérative @5 41
C07 04  X  ENG  @0 Degenerative disease @5 41
C07 04  X  SPA  @0 Enfermedad degenerativa @5 41
C07 05  X  FRE  @0 Pathologie du système nerveux central @5 42
C07 05  X  ENG  @0 Central nervous system disease @5 42
C07 05  X  SPA  @0 Sistema nervosio central patología @5 42
C07 06  X  FRE  @0 Appareil urinaire @5 43
C07 06  X  ENG  @0 Urinary system @5 43
C07 06  X  SPA  @0 Aparato urinario @5 43
C07 07  X  FRE  @0 Pathologie de l'appareil urinaire @5 44
C07 07  X  ENG  @0 Urinary system disease @5 44
C07 07  X  SPA  @0 Aparato urinario patología @5 44
C07 08  X  FRE  @0 Pathologie de la vessie @5 45
C07 08  X  ENG  @0 Bladder disease @5 45
C07 08  X  SPA  @0 Vejiga patología @5 45
C07 09  X  FRE  @0 Pathologie des voies urinaires @5 46
C07 09  X  ENG  @0 Urinary tract disease @5 46
C07 09  X  SPA  @0 Vía urinaria patología @5 46
N21       @1 042
N44 01      @1 OTO
N82       @1 OTO

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Pascal:13-0063581

Le document en format XML

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<title xml:lang="en" level="a">Weak Detrusor Contractility Correlates With Motor Disorders in Parkinson's Disease</title>
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<name sortKey="Ogawa, Akihiro" sort="Ogawa, Akihiro" uniqKey="Ogawa A" first="Akihiro" last="Ogawa">Akihiro Ogawa</name>
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<name sortKey="Haruta, Hiroyuki" sort="Haruta, Hiroyuki" uniqKey="Haruta H" first="Hiroyuki" last="Haruta">Hiroyuki Haruta</name>
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<name sortKey="Akiba, Takashi" sort="Akiba, Takashi" uniqKey="Akiba T" first="Takashi" last="Akiba">Takashi Akiba</name>
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<name sortKey="Nagao, Takeki" sort="Nagao, Takeki" uniqKey="Nagao T" first="Takeki" last="Nagao">Takeki Nagao</name>
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<s1>Neurosurgery, Sakura Medical Center, Toho University</s1>
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<name sortKey="Takahashi, Osamu" sort="Takahashi, Osamu" uniqKey="Takahashi O" first="Osamu" last="Takahashi">Osamu Takahashi</name>
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<name sortKey="Sugiyama, Megumi" sort="Sugiyama, Megumi" uniqKey="Sugiyama M" first="Megumi" last="Sugiyama">Megumi Sugiyama</name>
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<div type="abstract" xml:lang="en">Limited attention has been paid to the relationship between urinary symptoms or urodynamic findings and motor disorders in Parkinson's disease (PD). We aimed to correlate pressure-flow urodynamic parameters with video-gait analysis parameters in PD. We recruited 41 patients with PD (25 men and 16 women; age, 70.6 ± 8.5 years; H & Y motor grading: 2 [range, 1-3]; disease duration: 4 years [range, 1-7]; taking levodopa 300 mg/day [range, 100-400]). All patients underwent pressure-flow urodynamics (parameters: first sensation, bladder capacity, detrusor overactivity [noted in 24 patients], and Watts factor [WF]) and video-gait analysis (parameters: time and number of strides for 5-m gait [simple task] and time for timed up and go [complex task]). Statistical analysis was made by Mann-Whitney's U-test for analyzing the relation between detrusor over-activity and gait as well as Spearman's rank-correlation coefficient test for analyzing the relation between the remaining parameters and gait. We found no relation between filling-phase urodynamics (detrusor overactivity, first sensation, and bladder capacity) and video-gait analysis parameters. By contrast, we found a significant relation between voiding-phase urodynamics (WF, reflecting detrusor power) and all three video-gait analysis parameters (reflecting lower-half bradykinesia and loss of postural reflex) in our PD patients (P < 0.01). The close relation between the WF and motor disorders in the present study suggests that, though clinically mild, a weak detrusor in PD might have a central origin. We should follow postvoid residual volume carefully in PD patients with advanced gait disorder, because postvoid residual volume might increase in such patients. (.</div>
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