Movement Disorders (revue)

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Distinct Basal Ganglia Hyperechogenicity in Idiopathic Basal Ganglia Calcification

Identifieur interne : 002526 ( PascalFrancis/Curation ); précédent : 002525; suivant : 002527

Distinct Basal Ganglia Hyperechogenicity in Idiopathic Basal Ganglia Calcification

Auteurs : Norbert Brüggemann [Allemagne] ; Susanne A. Schneider [Allemagne] ; Thurid Sander [Allemagne] ; Christine Klein [Allemagne] ; Johann Hagenah [Allemagne]

Source :

RBID : Pascal:10-0512955

Descripteurs français

English descriptors

Abstract

We report a 67-year-old patient with idiopathic basal ganglia calcification (IBGC). He presented with progressive cognitive impairment, frontal lobe dysfunction, mild leg spasticity, and levodopa (L-dopa)-responsive parkinsonism. Transcranial sonography (TCS) revealed marked hyperechogenicity of the basal ganglia and periventricular spaces bilaterally. The detected signal alterations showed a fairly symmetric distribution and corresponded to the hyperintense calcifications depicted on the computer tomography brain scan. The combination of symmetric hyperechogenic areas adjacent to the lateral ventricles and of the basal ganglia may serve as an imaging marker characteristic of IBGC. Hyperechogenicity due to extended basal ganglia calcification as presented here is distinct from the pattern of hyperechogenicity caused by heavy metal accumulation, which is described to be less striking. In addition to atypical parkinsonian syndromes such as progressive supranuclear palsy and multiple system atrophy, IBGC is thus another differential diagnosis of parkinsonism with basal ganglia hyperechogenicity.
pA  
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A03   1    @0 Mov. disord.
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A08 01  1  ENG  @1 Distinct Basal Ganglia Hyperechogenicity in Idiopathic Basal Ganglia Calcification
A11 01  1    @1 BRÜGGEMANN (Norbert)
A11 02  1    @1 SCHNEIDER (Susanne A.)
A11 03  1    @1 SANDER (Thurid)
A11 04  1    @1 KLEIN (Christine)
A11 05  1    @1 HAGENAH (Johann)
A14 01      @1 Schilling Section of Clinical and Molecular Neurogenetics, University of Lübeck @2 Lübeck @3 DEU @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
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A44       @0 0000 @1 © 2010 INIST-CNRS. All rights reserved.
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C01 01    ENG  @0 We report a 67-year-old patient with idiopathic basal ganglia calcification (IBGC). He presented with progressive cognitive impairment, frontal lobe dysfunction, mild leg spasticity, and levodopa (L-dopa)-responsive parkinsonism. Transcranial sonography (TCS) revealed marked hyperechogenicity of the basal ganglia and periventricular spaces bilaterally. The detected signal alterations showed a fairly symmetric distribution and corresponded to the hyperintense calcifications depicted on the computer tomography brain scan. The combination of symmetric hyperechogenic areas adjacent to the lateral ventricles and of the basal ganglia may serve as an imaging marker characteristic of IBGC. Hyperechogenicity due to extended basal ganglia calcification as presented here is distinct from the pattern of hyperechogenicity caused by heavy metal accumulation, which is described to be less striking. In addition to atypical parkinsonian syndromes such as progressive supranuclear palsy and multiple system atrophy, IBGC is thus another differential diagnosis of parkinsonism with basal ganglia hyperechogenicity.
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C03 01  X  FRE  @0 Parkinsonisme @2 NM @5 01
C03 01  X  ENG  @0 Parkinsonism @2 NM @5 01
C03 01  X  SPA  @0 Parkinson síndrome @2 NM @5 01
C03 02  X  FRE  @0 Pathologie du système nerveux @5 02
C03 02  X  ENG  @0 Nervous system diseases @5 02
C03 02  X  SPA  @0 Sistema nervioso patología @5 02
C03 03  X  FRE  @0 Noyau gris central @5 09
C03 03  X  ENG  @0 Basal ganglion @5 09
C03 03  X  SPA  @0 Núcleo basal @5 09
C03 04  X  FRE  @0 Idiopathique @5 10
C03 04  X  ENG  @0 Idiopathic @5 10
C03 04  X  SPA  @0 Idiopático @5 10
C03 05  X  FRE  @0 Calcification @5 11
C03 05  X  ENG  @0 Calcification @5 11
C03 05  X  SPA  @0 Calcificación @5 11
C03 06  X  FRE  @0 Exploration ultrason @5 12
C03 06  X  ENG  @0 Sonography @5 12
C03 06  X  SPA  @0 Exploración ultrasonido @5 12
C07 01  X  FRE  @0 Encéphale @5 37
C07 01  X  ENG  @0 Encephalon @5 37
C07 01  X  SPA  @0 Encéfalo @5 37
C07 02  X  FRE  @0 Système nerveux central @5 38
C07 02  X  ENG  @0 Central nervous system @5 38
C07 02  X  SPA  @0 Sistema nervioso central @5 38
N21       @1 347
N44 01      @1 OTO
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<div type="abstract" xml:lang="en">We report a 67-year-old patient with idiopathic basal ganglia calcification (IBGC). He presented with progressive cognitive impairment, frontal lobe dysfunction, mild leg spasticity, and levodopa (L-dopa)-responsive parkinsonism. Transcranial sonography (TCS) revealed marked hyperechogenicity of the basal ganglia and periventricular spaces bilaterally. The detected signal alterations showed a fairly symmetric distribution and corresponded to the hyperintense calcifications depicted on the computer tomography brain scan. The combination of symmetric hyperechogenic areas adjacent to the lateral ventricles and of the basal ganglia may serve as an imaging marker characteristic of IBGC. Hyperechogenicity due to extended basal ganglia calcification as presented here is distinct from the pattern of hyperechogenicity caused by heavy metal accumulation, which is described to be less striking. In addition to atypical parkinsonian syndromes such as progressive supranuclear palsy and multiple system atrophy, IBGC is thus another differential diagnosis of parkinsonism with basal ganglia hyperechogenicity.</div>
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<fC03 i1="05" i2="X" l="FRE">
<s0>Calcification</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Calcification</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Calcificación</s0>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Exploration ultrason</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Sonography</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Exploración ultrasonido</s0>
<s5>12</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Encéphale</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Encephalon</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Encéfalo</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Système nerveux central</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Central nervous system</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Sistema nervioso central</s0>
<s5>38</s5>
</fC07>
<fN21>
<s1>347</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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