Movement Disorders (revue)

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Executive Dysfunction Using Behavioral Assessment of the Dysexecutive Syndrome in Parkinson's Disease

Identifieur interne : 001A11 ( PascalFrancis/Curation ); précédent : 001A10; suivant : 001A12

Executive Dysfunction Using Behavioral Assessment of the Dysexecutive Syndrome in Parkinson's Disease

Auteurs : Satoshi Kamei [Japon] ; Motohiko Hara [Japon] ; Kan Serizawa [Japon] ; Masato Murakami [Japon] ; Tomohiko Mizutani [Japon] ; Motoko Ishiburo [Japon] ; Ritsuko Kawahara [Japon] ; Yukiko Takagi [Japon] ; Katsuhiko Ogawa [Japon] ; Hirokazu Yoshihashi [Japon] ; Satoru Shinbo [Japon] ; Yutaka Suzuki [Japon] ; Mai Yamaguchi [Japon] ; Akihiko Morita [Japon] ; Jun Takeshita [Japon] ; Kaname Hirayanagi [Japon]

Source :

RBID : Pascal:08-0199303

Descripteurs français

English descriptors

Abstract

The objective of this study was to evaluate the executive dysfunction (ExD) in Parkinson's disease (PD) using the Behavioral Assessment of the Dysexecutive Syndrome (BADS), which provides a wide-range assessment of ExD. The BADS and the Unified Parkinson's Disease Rating Scale (UPDRS) were investigated in 63 nondemented PD patients who revealed scores of ≥24 points on the Mini-Mental State Examination based on the DSM-IV. Multiple logistic regression analysis was performed to evaluate the predisposing factors to ExD, which was defined as <70 points on the age-controlled standardized score. The total score on the UPDRS was a significant independent predisposing factor to ExD. Among the various parts of the UPDRS, part II was the significant factor for ExD. The profile scores of all subtests on the BADS in patients with ExD were significantly lower than those of patients without ExD. All profile scores decreased with severity of PD, but the changes among these scores differed. ExD in nondemented PD predisposed to a greater severity of PD, particularly as regards the activity of daily living impairment. Nondemented PD revealed wide-range components of ExD. All components of ExD were impaired with severity of PD, but the patterns of each component exhibited variety.
pA  
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A03   1    @0 Mov. disord.
A05       @2 23
A06       @2 4
A08 01  1  ENG  @1 Executive Dysfunction Using Behavioral Assessment of the Dysexecutive Syndrome in Parkinson's Disease
A11 01  1    @1 KAMEI (Satoshi)
A11 02  1    @1 HARA (Motohiko)
A11 03  1    @1 SERIZAWA (Kan)
A11 04  1    @1 MURAKAMI (Masato)
A11 05  1    @1 MIZUTANI (Tomohiko)
A11 06  1    @1 ISHIBURO (Motoko)
A11 07  1    @1 KAWAHARA (Ritsuko)
A11 08  1    @1 TAKAGI (Yukiko)
A11 09  1    @1 OGAWA (Katsuhiko)
A11 10  1    @1 YOSHIHASHI (Hirokazu)
A11 11  1    @1 SHINBO (Satoru)
A11 12  1    @1 SUZUKI (Yutaka)
A11 13  1    @1 YAMAGUCHI (Mai)
A11 14  1    @1 MORITA (Akihiko)
A11 15  1    @1 TAKESHITA (Jun)
A11 16  1    @1 HIRAYANAGI (Kaname)
A14 01      @1 Division of Neurology, Department of Medicine, Nihon University School of Medicine @2 Tokyo @3 JPN @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 5 aut. @Z 9 aut. @Z 10 aut. @Z 11 aut. @Z 12 aut. @Z 13 aut. @Z 14 aut. @Z 15 aut.
A14 02      @1 Clinic of Psychosomatic Medicine, Nihon University Itabashi Hospital @2 Tokyo @3 JPN @Z 4 aut. @Z 6 aut. @Z 7 aut. @Z 8 aut.
A14 03      @1 Department of Hygiene and Public Health, Nihon University of Physical Education @2 Tokyo @3 JPN @Z 16 aut.
A20       @1 566-573
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000183361080120
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
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A47 01  1    @0 08-0199303
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 The objective of this study was to evaluate the executive dysfunction (ExD) in Parkinson's disease (PD) using the Behavioral Assessment of the Dysexecutive Syndrome (BADS), which provides a wide-range assessment of ExD. The BADS and the Unified Parkinson's Disease Rating Scale (UPDRS) were investigated in 63 nondemented PD patients who revealed scores of ≥24 points on the Mini-Mental State Examination based on the DSM-IV. Multiple logistic regression analysis was performed to evaluate the predisposing factors to ExD, which was defined as <70 points on the age-controlled standardized score. The total score on the UPDRS was a significant independent predisposing factor to ExD. Among the various parts of the UPDRS, part II was the significant factor for ExD. The profile scores of all subtests on the BADS in patients with ExD were significantly lower than those of patients without ExD. All profile scores decreased with severity of PD, but the changes among these scores differed. ExD in nondemented PD predisposed to a greater severity of PD, particularly as regards the activity of daily living impairment. Nondemented PD revealed wide-range components of ExD. All components of ExD were impaired with severity of PD, but the patterns of each component exhibited variety.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Trouble cognitif @5 01
C03 01  X  ENG  @0 Cognitive disorder @5 01
C03 01  X  SPA  @0 Trastorno cognitivo @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
C03 02  X  ENG  @0 Parkinson disease @2 NM @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
C03 03  X  FRE  @0 Pathologie du système nerveux @5 03
C03 03  X  ENG  @0 Nervous system diseases @5 03
C03 03  X  SPA  @0 Sistema nervioso patología @5 03
C03 04  X  FRE  @0 Fonction exécutive @5 09
C03 04  X  ENG  @0 Executive function @5 09
C03 04  X  SPA  @0 Función ejecutiva @5 09
C03 05  X  FRE  @0 Facteur risque @5 10
C03 05  X  ENG  @0 Risk factor @5 10
C03 05  X  SPA  @0 Factor riesgo @5 10
C03 06  X  FRE  @0 Echelle d'évaluation @5 11
C03 06  X  ENG  @0 Evaluation scale @5 11
C03 06  X  SPA  @0 Escala evaluación @5 11
C07 01  X  FRE  @0 Pathologie de l'encéphale @5 37
C07 01  X  ENG  @0 Cerebral disorder @5 37
C07 01  X  SPA  @0 Encéfalo patología @5 37
C07 02  X  FRE  @0 Syndrome extrapyramidal @5 38
C07 02  X  ENG  @0 Extrapyramidal syndrome @5 38
C07 02  X  SPA  @0 Extrapiramidal síndrome @5 38
C07 03  X  FRE  @0 Maladie dégénérative @5 39
C07 03  X  ENG  @0 Degenerative disease @5 39
C07 03  X  SPA  @0 Enfermedad degenerativa @5 39
C07 04  X  FRE  @0 Pathologie du système nerveux central @5 40
C07 04  X  ENG  @0 Central nervous system disease @5 40
C07 04  X  SPA  @0 Sistema nervosio central patología @5 40
N21       @1 126
N44 01      @1 OTO
N82       @1 OTO

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Pascal:08-0199303

Le document en format XML

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<title xml:lang="en" level="a">Executive Dysfunction Using Behavioral Assessment of the Dysexecutive Syndrome in Parkinson's Disease</title>
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<div type="abstract" xml:lang="en">The objective of this study was to evaluate the executive dysfunction (ExD) in Parkinson's disease (PD) using the Behavioral Assessment of the Dysexecutive Syndrome (BADS), which provides a wide-range assessment of ExD. The BADS and the Unified Parkinson's Disease Rating Scale (UPDRS) were investigated in 63 nondemented PD patients who revealed scores of ≥24 points on the Mini-Mental State Examination based on the DSM-IV. Multiple logistic regression analysis was performed to evaluate the predisposing factors to ExD, which was defined as <70 points on the age-controlled standardized score. The total score on the UPDRS was a significant independent predisposing factor to ExD. Among the various parts of the UPDRS, part II was the significant factor for ExD. The profile scores of all subtests on the BADS in patients with ExD were significantly lower than those of patients without ExD. All profile scores decreased with severity of PD, but the changes among these scores differed. ExD in nondemented PD predisposed to a greater severity of PD, particularly as regards the activity of daily living impairment. Nondemented PD revealed wide-range components of ExD. All components of ExD were impaired with severity of PD, but the patterns of each component exhibited variety.</div>
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