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Transcranial Sonography Findings in Welding-Related Parkinsonism in Comparison to Parkinson's Disease

Identifieur interne : 001919 ( PascalFrancis/Curation ); précédent : 001918; suivant : 001920

Transcranial Sonography Findings in Welding-Related Parkinsonism in Comparison to Parkinson's Disease

Auteurs : Uwe Walter [Allemagne] ; Dirk Dressier [Allemagne] ; Christian Lindemann [Chili] ; Andrea Slachevsky [Chili] ; Marcelo Miranda [Chili]

Source :

RBID : Pascal:08-0115913

Descripteurs français

English descriptors

Abstract

The pathogenetic relationship of welding-related Parkinsonism (WP) and idiopathic Parkinson's disease (PD) is a matter of debate. In the present study, we compared transcranial sonography (TCS) findings in patients with WP and PD. Two male patients with WP, who had developed levodopa-resistant akinetic-rigid Parkinsonism without ongoing progression after having worked as welders for many years in Chilean mines in confined spaces without adequate ventilation, and three age-matched male patients with clinically definite akinetic-rigid PD were studied with TCS in a random order by two investigators blind to clinical diagnoses. In both WP patients, normal echogenicity of substantia nigra was found whereas all PD patients exhibited marked substantia nigra hyperechogenicity, previously reported as a characteristic TCS finding in idiopathic PD. In contrast, lenticular nucleus was hyperechogenic in both WP patients but only in one of the PD patients. TCS findings suggest a different pathophysiology of Parkinsonism in WP and PD patients.
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A08 01  1  ENG  @1 Transcranial Sonography Findings in Welding-Related Parkinsonism in Comparison to Parkinson's Disease
A11 01  1    @1 WALTER (Uwe)
A11 02  1    @1 DRESSIER (Dirk)
A11 03  1    @1 LINDEMANN (Christian)
A11 04  1    @1 SLACHEVSKY (Andrea)
A11 05  1    @1 MIRANDA (Marcelo)
A14 01      @1 Department of Neurology, University of Rostock @2 Rostock @3 DEU @Z 1 aut. @Z 2 aut.
A14 02      @1 Department of Radiology, Clinica Las Condes @2 Santiago @3 CHL @Z 3 aut.
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A47 01  1    @0 08-0115913
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C01 01    ENG  @0 The pathogenetic relationship of welding-related Parkinsonism (WP) and idiopathic Parkinson's disease (PD) is a matter of debate. In the present study, we compared transcranial sonography (TCS) findings in patients with WP and PD. Two male patients with WP, who had developed levodopa-resistant akinetic-rigid Parkinsonism without ongoing progression after having worked as welders for many years in Chilean mines in confined spaces without adequate ventilation, and three age-matched male patients with clinically definite akinetic-rigid PD were studied with TCS in a random order by two investigators blind to clinical diagnoses. In both WP patients, normal echogenicity of substantia nigra was found whereas all PD patients exhibited marked substantia nigra hyperechogenicity, previously reported as a characteristic TCS finding in idiopathic PD. In contrast, lenticular nucleus was hyperechogenic in both WP patients but only in one of the PD patients. TCS findings suggest a different pathophysiology of Parkinsonism in WP and PD patients.
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C03 01  X  FRE  @0 Parkinsonisme @2 NM @5 01
C03 01  X  ENG  @0 Parkinsonism @2 NM @5 01
C03 01  X  SPA  @0 Parkinson síndrome @2 NM @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
C03 02  X  ENG  @0 Parkinson disease @2 NM @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
C03 03  X  FRE  @0 Pathologie du système nerveux @5 03
C03 03  X  ENG  @0 Nervous system diseases @5 03
C03 03  X  SPA  @0 Sistema nervioso patología @5 03
C03 04  X  FRE  @0 Exploration ultrason @5 09
C03 04  X  ENG  @0 Sonography @5 09
C03 04  X  SPA  @0 Exploración ultrasonido @5 09
C03 05  X  FRE  @0 Etude comparative @5 10
C03 05  X  ENG  @0 Comparative study @5 10
C03 05  X  SPA  @0 Estudio comparativo @5 10
C03 06  X  FRE  @0 Encéphale @5 11
C03 06  X  ENG  @0 Encephalon @5 11
C03 06  X  SPA  @0 Encéfalo @5 11
C03 07  X  FRE  @0 Locus niger @5 12
C03 07  X  ENG  @0 Locus niger @5 12
C03 07  X  SPA  @0 Locus níger @5 12
C07 01  X  FRE  @0 Pathologie de l'encéphale @5 38
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C07 01  X  SPA  @0 Encéfalo patología @5 38
C07 02  X  FRE  @0 Syndrome extrapyramidal @5 39
C07 02  X  ENG  @0 Extrapyramidal syndrome @5 39
C07 02  X  SPA  @0 Extrapiramidal síndrome @5 39
C07 03  X  FRE  @0 Maladie dégénérative @5 40
C07 03  X  ENG  @0 Degenerative disease @5 40
C07 03  X  SPA  @0 Enfermedad degenerativa @5 40
C07 04  X  FRE  @0 Pathologie du système nerveux central @5 41
C07 04  X  ENG  @0 Central nervous system disease @5 41
C07 04  X  SPA  @0 Sistema nervosio central patología @5 41
C07 05  X  FRE  @0 Système nerveux central @5 42
C07 05  X  ENG  @0 Central nervous system @5 42
C07 05  X  SPA  @0 Sistema nervioso central @5 42
N21       @1 063
N44 01      @1 OTO
N82       @1 OTO

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Pascal:08-0115913

Le document en format XML

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<s0>Sistema nervioso central</s0>
<s5>42</s5>
</fC07>
<fN21>
<s1>063</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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