Movement Disorders (revue)

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Long lasting pure freezing of gait preceding progressive supranuclear palsy : A clinicopathological study

Identifieur interne : 001816 ( PascalFrancis/Curation ); précédent : 001815; suivant : 001817

Long lasting pure freezing of gait preceding progressive supranuclear palsy : A clinicopathological study

Auteurs : Yaroslau Compta [Espagne] ; Francesc Valldeoriola [Espagne] ; Eduardo Tolosa [Espagne] ; Maria Jestis Rey [Espagne] ; Maria Jose Marti [Espagne] ; Josep Valls-Sole [Espagne]

Source :

RBID : Pascal:08-0015798

Descripteurs français

English descriptors

Abstract

Primary progressive freezing of gait (PPFG) is the term used to designate an uncommon condition featuring freezing of gait with frequent falls, without bradykinesia, rigidity or tremor, and unresponsive to levodopa. There are very few pathological reports of patients with PPFG in the literature. We report on 2 patients (one with pathological confirmation) diagnosed initially as PPFG and evolving into clinically defined progressive supranuclear palsy (PSP) more than 10 years after onset of symptoms. These 2 cases suggest that PPFG can represent the initial manifestation of a neurodegenerative disease, such as PSP, rather than a differentiated nosological entity.
pA  
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A08 01  1  ENG  @1 Long lasting pure freezing of gait preceding progressive supranuclear palsy : A clinicopathological study
A11 01  1    @1 COMPTA (Yaroslau)
A11 02  1    @1 VALLDEORIOLA (Francesc)
A11 03  1    @1 TOLOSA (Eduardo)
A11 04  1    @1 JESTIS REY (Maria)
A11 05  1    @1 MARTI (Maria Jose)
A11 06  1    @1 VALLS-SOLE (Josep)
A14 01      @1 Servei de Neurologia, Institut Clinic de Neurociències, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic de Barcelona @2 Barcelona, Catalonia @3 ESP @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 5 aut. @Z 6 aut.
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C01 01    ENG  @0 Primary progressive freezing of gait (PPFG) is the term used to designate an uncommon condition featuring freezing of gait with frequent falls, without bradykinesia, rigidity or tremor, and unresponsive to levodopa. There are very few pathological reports of patients with PPFG in the literature. We report on 2 patients (one with pathological confirmation) diagnosed initially as PPFG and evolving into clinically defined progressive supranuclear palsy (PSP) more than 10 years after onset of symptoms. These 2 cases suggest that PPFG can represent the initial manifestation of a neurodegenerative disease, such as PSP, rather than a differentiated nosological entity.
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C03 01  X  ENG  @0 Nervous system diseases @5 01
C03 01  X  SPA  @0 Sistema nervioso patología @5 01
C03 02  X  FRE  @0 Trouble de la marche @5 02
C03 02  X  ENG  @0 Gait disorder @5 02
C03 02  X  SPA  @0 Trastorno marcha @5 02
C03 03  X  FRE  @0 Longue durée @5 09
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C03 03  X  SPA  @0 Larga duración @5 09
C03 04  X  FRE  @0 Congélation @5 10
C03 04  X  ENG  @0 Freezing @5 10
C03 04  X  SPA  @0 Congelación @5 10
N21       @1 009
N44 01      @1 OTO
N82       @1 OTO

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Pascal:08-0015798

Le document en format XML

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