Movement Disorders (revue)

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Postural sway and falls in parkinson's disease : A regression approach

Identifieur interne : 001812 ( PascalFrancis/Curation ); précédent : 001811; suivant : 001813

Postural sway and falls in parkinson's disease : A regression approach

Auteurs : Maarit Matinolli [Finlande] ; Juha T. Korpelainen [Finlande] ; Raija Korpelainen [Finlande] ; Kyösti A. Sotaniemi [Finlande] ; Minna Virranniemi [Finlande] ; Vilho V. Myllyl [Finlande]

Source :

RBID : Pascal:08-0015794

Descripteurs français

English descriptors

Abstract

A population-based study was designed to evaluate the clinical associates of postural sway and to identify the risk factors for falls in Parkinson's disease (PD). From a total population of 205,000 inhabitants, 215 PD patients were identified of which 120 home-dwelling cases were finally included in the study. Medical data were collected and patients were clinically examined and tested for static balance using an inclinometric device. Recent falls occurred in 40 (33%) of the subjects and 27 (23%) subjects were recurrent fallers. The fallers had a significantly larger sway area (P = 0.021) and a larger maximum deflection in anterior-posterior (P = 0.016) and lateral directions (P = 0.006) than the nonfallers. A significant correlation was found between the sway measures and the UPDRS total score, motor subcore and UPDRS "bradykinesia" item. A higher UPDRS total score (OR: 1.04, 95% CI: 1.01-1.07) and an increased sway area (OR: 1.25, 95% CI: 1.02-1.54) were independent risk factors for recent falling in PD. In addition, the duration and severity of PD, antiparkinsonian medication, recent falling and the use of a walking aid were associated with increased sway measures. The results can be used to identify PD patients who are at a risk of falling. Both antiparkinsonian medication and nonmedical treatment should be optimized to reduce falls in PD.
pA  
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A03   1    @0 Mov. disord.
A05       @2 22
A06       @2 13
A08 01  1  ENG  @1 Postural sway and falls in parkinson's disease : A regression approach
A11 01  1    @1 MATINOLLI (Maarit)
A11 02  1    @1 KORPELAINEN (Juha T.)
A11 03  1    @1 KORPELAINEN (Raija)
A11 04  1    @1 SOTANIEMI (Kyösti A.)
A11 05  1    @1 VIRRANNIEMI (Minna)
A11 06  1    @1 MYLLYLÄ (Vilho V.)
A14 01      @1 Department of Neurology, University of Oulu @2 Oulu @3 FIN @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut.
A14 02      @1 Department of Sports Medicine, Deaconess Institute of Oulu @2 Oulu @3 FIN @Z 3 aut.
A14 03      @1 Department of Public Health and General Practice, University of Oulu @2 Oulu @3 FIN @Z 3 aut.
A20       @1 1927-1935
A21       @1 2007
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000173554140130
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 36 ref.
A47 01  1    @0 08-0015794
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 A population-based study was designed to evaluate the clinical associates of postural sway and to identify the risk factors for falls in Parkinson's disease (PD). From a total population of 205,000 inhabitants, 215 PD patients were identified of which 120 home-dwelling cases were finally included in the study. Medical data were collected and patients were clinically examined and tested for static balance using an inclinometric device. Recent falls occurred in 40 (33%) of the subjects and 27 (23%) subjects were recurrent fallers. The fallers had a significantly larger sway area (P = 0.021) and a larger maximum deflection in anterior-posterior (P = 0.016) and lateral directions (P = 0.006) than the nonfallers. A significant correlation was found between the sway measures and the UPDRS total score, motor subcore and UPDRS "bradykinesia" item. A higher UPDRS total score (OR: 1.04, 95% CI: 1.01-1.07) and an increased sway area (OR: 1.25, 95% CI: 1.02-1.54) were independent risk factors for recent falling in PD. In addition, the duration and severity of PD, antiparkinsonian medication, recent falling and the use of a walking aid were associated with increased sway measures. The results can be used to identify PD patients who are at a risk of falling. Both antiparkinsonian medication and nonmedical treatment should be optimized to reduce falls in PD.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C02 03  X    @0 002B17A03
C03 01  X  FRE  @0 Pathologie du système nerveux @5 01
C03 01  X  ENG  @0 Nervous system diseases @5 01
C03 01  X  SPA  @0 Sistema nervioso patología @5 01
C03 02  X  FRE  @0 Trouble de l'équilibre @5 02
C03 02  X  ENG  @0 Equilibrium disorder @5 02
C03 02  X  SPA  @0 Trastorno equilibrio @5 02
C03 03  X  FRE  @0 Maladie de Parkinson @2 NM @5 03
C03 03  X  ENG  @0 Parkinson disease @2 NM @5 03
C03 03  X  SPA  @0 Parkinson enfermedad @2 NM @5 03
C03 04  X  FRE  @0 Voie abord @5 09
C03 04  X  ENG  @0 Surgical approach @5 09
C03 04  X  SPA  @0 Vía abordaje @5 09
C07 01  X  FRE  @0 Pathologie ORL @5 37
C07 01  X  ENG  @0 ENT disease @5 37
C07 01  X  SPA  @0 ORL patología @5 37
C07 02  X  FRE  @0 Pathologie de l'encéphale @5 39
C07 02  X  ENG  @0 Cerebral disorder @5 39
C07 02  X  SPA  @0 Encéfalo patología @5 39
C07 03  X  FRE  @0 Syndrome extrapyramidal @5 40
C07 03  X  ENG  @0 Extrapyramidal syndrome @5 40
C07 03  X  SPA  @0 Extrapiramidal síndrome @5 40
C07 04  X  FRE  @0 Maladie dégénérative @5 41
C07 04  X  ENG  @0 Degenerative disease @5 41
C07 04  X  SPA  @0 Enfermedad degenerativa @5 41
C07 05  X  FRE  @0 Pathologie du système nerveux central @5 42
C07 05  X  ENG  @0 Central nervous system disease @5 42
C07 05  X  SPA  @0 Sistema nervosio central patología @5 42
N21       @1 009
N44 01      @1 OTO
N82       @1 OTO

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Pascal:08-0015794

Le document en format XML

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<div type="abstract" xml:lang="en">A population-based study was designed to evaluate the clinical associates of postural sway and to identify the risk factors for falls in Parkinson's disease (PD). From a total population of 205,000 inhabitants, 215 PD patients were identified of which 120 home-dwelling cases were finally included in the study. Medical data were collected and patients were clinically examined and tested for static balance using an inclinometric device. Recent falls occurred in 40 (33%) of the subjects and 27 (23%) subjects were recurrent fallers. The fallers had a significantly larger sway area (P = 0.021) and a larger maximum deflection in anterior-posterior (P = 0.016) and lateral directions (P = 0.006) than the nonfallers. A significant correlation was found between the sway measures and the UPDRS total score, motor subcore and UPDRS "bradykinesia" item. A higher UPDRS total score (OR: 1.04, 95% CI: 1.01-1.07) and an increased sway area (OR: 1.25, 95% CI: 1.02-1.54) were independent risk factors for recent falling in PD. In addition, the duration and severity of PD, antiparkinsonian medication, recent falling and the use of a walking aid were associated with increased sway measures. The results can be used to identify PD patients who are at a risk of falling. Both antiparkinsonian medication and nonmedical treatment should be optimized to reduce falls in PD.</div>
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<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Trouble de l'équilibre</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Equilibrium disorder</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Trastorno equilibrio</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Maladie de Parkinson</s0>
<s2>NM</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Parkinson disease</s0>
<s2>NM</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Parkinson enfermedad</s0>
<s2>NM</s2>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Voie abord</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Surgical approach</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Vía abordaje</s0>
<s5>09</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Pathologie ORL</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>ENT disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>ORL patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Pathologie de l'encéphale</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Syndrome extrapyramidal</s0>
<s5>40</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Pathologie du système nerveux central</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>42</s5>
</fC07>
<fN21>
<s1>009</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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