MovDisordV3, PascalFrancis, Curation, bibRecord, 001530

Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation

Identifieur interne : 001530 ( PascalFrancis/Curation ); précédent : 001529; suivant : 001531

Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation

Auteurs : Maria Teresa Giordana [Italie] ; Carla D'Agostino [Italie] ; Giovanni Albani [Italie] ; Alessandro Mauro [Italie] ; Alessio Di Fonzo [Pays-Bas, Italie] ; Angelo Antonini [Italie] ; Vincenzo Bonifati [Pays-Bas]

Source :

Movement disorders [ 0885-3185 ] ; 2007.

RBID : Pascal:07-0133261

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinson maladie, Mutation.

English descriptors

KwdEn :
- Mutation, Nervous system diseases, Parkinson disease.

Abstract

Leucine-Rich Repeat Kinase 2 (LRRK2) gene mutations are the most common known cause of Parkinson's disease (PD), but neuropathological studies are available on very few patients with LRRK2 mutation. The reported findings range from Lewy body-positive pathology to different pathologies, including nigral degeneration without distinctive features, neuronal loss with only ubiquitin-positive inclusions, and tau-positive-only pathology. Here we report the first neuropathological study in an Italian PD case carrying a different LRRK2 mutation, Ile1371Val, and showing typical ubiquitin- and α-synuclein-positive Lewy body pathology. These findings support the concept that the neurodegeneration associated with LRRK2 mutations might be clinically and pathologically indistinguishable from typical PD.

A01	`01`	`1`		`@0 0885-3185`
A03		`1`		`@0 Mov. disord.`
A05				`@2 22`
A06				`@2 2`
A08	`01`	`1`	`ENG`	`@1 Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation`
A11	`01`	`1`		`@1 GIORDANA (Maria Teresa)`
A11	`02`	`1`		`@1 D'AGOSTINO (Carla)`
A11	`03`	`1`		`@1 ALBANI (Giovanni)`
A11	`04`	`1`		`@1 MAURO (Alessandro)`
A11	`05`	`1`		`@1 DI FONZO (Alessio)`
A11	`06`	`1`		`@1 ANTONINI (Angelo)`
A11	`07`	`1`		`@1 BONIFATI (Vincenzo)`
A14	`01`			`@1 Department of Neuroscience, University of Torino @2 Torino @3 ITA @Z 1 aut. @Z 2 aut. @Z 4 aut.`
A14	`02`			`@1 Department of Neurology, Istituto Auxologico Italiano @2 Piancavallo, Verbania @3 ITA @Z 3 aut. @Z 4 aut.`
A14	`03`			`@1 Department of Clinical Genetics, Erasmus MC Rotterdam @2 Rotterdam @3 NLD @Z 5 aut. @Z 7 aut.`
A14	`04`			`@1 Department of Neurological Sciences, University of Milan and Foundation Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena @2 Milan @3 ITA @Z 5 aut.`
A14	`05`			`@1 Parkinson Institute, Istituti Clinici di Perfezionamento @2 Milan @3 ITA @Z 6 aut.`
A20				`@1 275-278`
A21				`@1 2007`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000145528070260`
A44				`@0 0000 @1 © 2007 INIST-CNRS. All rights reserved.`
A45				`@0 22 ref.`
A47	`01`	`1`		`@0 07-0133261`
A60				`@1 P @3 CC`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Leucine-Rich Repeat Kinase 2 (LRRK2) gene mutations are the most common known cause of Parkinson's disease (PD), but neuropathological studies are available on very few patients with LRRK2 mutation. The reported findings range from Lewy body-positive pathology to different pathologies, including nigral degeneration without distinctive features, neuronal loss with only ubiquitin-positive inclusions, and tau-positive-only pathology. Here we report the first neuropathological study in an Italian PD case carrying a different LRRK2 mutation, Ile1371Val, and showing typical ubiquitin- and α-synuclein-positive Lewy body pathology. These findings support the concept that the neurodegeneration associated with LRRK2 mutations might be clinically and pathologically indistinguishable from typical PD.
C02	`01`	`X`		`@0 002B17`
C02	`02`	`X`		`@0 002B17G`
C02	`03`	`X`		`@0 002B17A03`
C03	`01`	`X`	`FRE`	`@0 Système nerveux pathologie @5 01`
C03	`01`	`X`	`ENG`	`@0 Nervous system diseases @5 01`
C03	`01`	`X`	`SPA`	`@0 Sistema nervioso patología @5 01`
C03	`02`	`X`	`FRE`	`@0 Parkinson maladie @5 02`
C03	`02`	`X`	`ENG`	`@0 Parkinson disease @5 02`
C03	`02`	`X`	`SPA`	`@0 Parkinson enfermedad @5 02`
C03	`03`	`X`	`FRE`	`@0 Mutation @5 09`
C03	`03`	`X`	`ENG`	`@0 Mutation @5 09`
C03	`03`	`X`	`SPA`	`@0 Mutación @5 09`
C07	`01`	`X`	`FRE`	`@0 Encéphale pathologie @5 37`
C07	`01`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`01`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 38`
C07	`03`	`X`	`FRE`	`@0 Maladie dégénérative @5 39`
C07	`03`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
C07	`04`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 40`
C07	`04`	`X`	`ENG`	`@0 Central nervous system disease @5 40`
C07	`04`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 40`
N21				`@1 085`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001791

Links to Exploration step

Pascal:07-0133261

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation</title>
<author><name sortKey="Giordana, Maria Teresa" sort="Giordana, Maria Teresa" uniqKey="Giordana M" first="Maria Teresa" last="Giordana">Maria Teresa Giordana</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neuroscience, University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="D Agostino, Carla" sort="D Agostino, Carla" uniqKey="D Agostino C" first="Carla" last="D'Agostino">Carla D'Agostino</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neuroscience, University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Albani, Giovanni" sort="Albani, Giovanni" uniqKey="Albani G" first="Giovanni" last="Albani">Giovanni Albani</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Istituto Auxologico Italiano</s1>
<s2>Piancavallo, Verbania</s2>
<s3>ITA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Mauro, Alessandro" sort="Mauro, Alessandro" uniqKey="Mauro A" first="Alessandro" last="Mauro">Alessandro Mauro</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neuroscience, University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Istituto Auxologico Italiano</s1>
<s2>Piancavallo, Verbania</s2>
<s3>ITA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Di Fonzo, Alessio" sort="Di Fonzo, Alessio" uniqKey="Di Fonzo A" first="Alessio" last="Di Fonzo">Alessio Di Fonzo</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Genetics, Erasmus MC Rotterdam</s1>
<s2>Rotterdam</s2>
<s3>NLD</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Neurological Sciences, University of Milan and Foundation Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena</s1>
<s2>Milan</s2>
<s3>ITA</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Parkinson Institute, Istituti Clinici di Perfezionamento</s1>
<s2>Milan</s2>
<s3>ITA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Bonifati, Vincenzo" sort="Bonifati, Vincenzo" uniqKey="Bonifati V" first="Vincenzo" last="Bonifati">Vincenzo Bonifati</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Genetics, Erasmus MC Rotterdam</s1>
<s2>Rotterdam</s2>
<s3>NLD</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">07-0133261</idno>
<date when="2007">2007</date>
<idno type="stanalyst">PASCAL 07-0133261 INIST</idno>
<idno type="RBID">Pascal:07-0133261</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001791</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001530</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation</title>
<author><name sortKey="Giordana, Maria Teresa" sort="Giordana, Maria Teresa" uniqKey="Giordana M" first="Maria Teresa" last="Giordana">Maria Teresa Giordana</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neuroscience, University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="D Agostino, Carla" sort="D Agostino, Carla" uniqKey="D Agostino C" first="Carla" last="D'Agostino">Carla D'Agostino</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neuroscience, University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Albani, Giovanni" sort="Albani, Giovanni" uniqKey="Albani G" first="Giovanni" last="Albani">Giovanni Albani</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Istituto Auxologico Italiano</s1>
<s2>Piancavallo, Verbania</s2>
<s3>ITA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Mauro, Alessandro" sort="Mauro, Alessandro" uniqKey="Mauro A" first="Alessandro" last="Mauro">Alessandro Mauro</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neuroscience, University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Neurology, Istituto Auxologico Italiano</s1>
<s2>Piancavallo, Verbania</s2>
<s3>ITA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Di Fonzo, Alessio" sort="Di Fonzo, Alessio" uniqKey="Di Fonzo A" first="Alessio" last="Di Fonzo">Alessio Di Fonzo</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Genetics, Erasmus MC Rotterdam</s1>
<s2>Rotterdam</s2>
<s3>NLD</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Neurological Sciences, University of Milan and Foundation Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena</s1>
<s2>Milan</s2>
<s3>ITA</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Antonini, Angelo" sort="Antonini, Angelo" uniqKey="Antonini A" first="Angelo" last="Antonini">Angelo Antonini</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Parkinson Institute, Istituti Clinici di Perfezionamento</s1>
<s2>Milan</s2>
<s3>ITA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Bonifati, Vincenzo" sort="Bonifati, Vincenzo" uniqKey="Bonifati V" first="Vincenzo" last="Bonifati">Vincenzo Bonifati</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Genetics, Erasmus MC Rotterdam</s1>
<s2>Rotterdam</s2>
<s3>NLD</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2007">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Mutation</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Parkinson maladie</term>
<term>Mutation</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Leucine-Rich Repeat Kinase 2 (LRRK2) gene mutations are the most common known cause of Parkinson's disease (PD), but neuropathological studies are available on very few patients with LRRK2 mutation. The reported findings range from Lewy body-positive pathology to different pathologies, including nigral degeneration without distinctive features, neuronal loss with only ubiquitin-positive inclusions, and tau-positive-only pathology. Here we report the first neuropathological study in an Italian PD case carrying a different LRRK2 mutation, Ile1371Val, and showing typical ubiquitin- and α-synuclein-positive Lewy body pathology. These findings support the concept that the neurodegeneration associated with LRRK2 mutations might be clinically and pathologically indistinguishable from typical PD.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0>
</fA01>
<fA03 i2="1"><s0>Mov. disord.</s0>
</fA03>
<fA05><s2>22</s2>
</fA05>
<fA06><s2>2</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>GIORDANA (Maria Teresa)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>D'AGOSTINO (Carla)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>ALBANI (Giovanni)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>MAURO (Alessandro)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>DI FONZO (Alessio)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>ANTONINI (Angelo)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>BONIFATI (Vincenzo)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Neuroscience, University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Department of Neurology, Istituto Auxologico Italiano</s1>
<s2>Piancavallo, Verbania</s2>
<s3>ITA</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Department of Clinical Genetics, Erasmus MC Rotterdam</s1>
<s2>Rotterdam</s2>
<s3>NLD</s3>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Department of Neurological Sciences, University of Milan and Foundation Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena</s1>
<s2>Milan</s2>
<s3>ITA</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Parkinson Institute, Istituti Clinici di Perfezionamento</s1>
<s2>Milan</s2>
<s3>ITA</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA20><s1>275-278</s1>
</fA20>
<fA21><s1>2007</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>20953</s2>
<s5>354000145528070260</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2007 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>22 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>07-0133261</s0>
</fA47>
<fA60><s1>P</s1>
<s3>CC</s3>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Movement disorders</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Leucine-Rich Repeat Kinase 2 (LRRK2) gene mutations are the most common known cause of Parkinson's disease (PD), but neuropathological studies are available on very few patients with LRRK2 mutation. The reported findings range from Lewy body-positive pathology to different pathologies, including nigral degeneration without distinctive features, neuronal loss with only ubiquitin-positive inclusions, and tau-positive-only pathology. Here we report the first neuropathological study in an Italian PD case carrying a different LRRK2 mutation, Ile1371Val, and showing typical ubiquitin- and α-synuclein-positive Lewy body pathology. These findings support the concept that the neurodegeneration associated with LRRK2 mutations might be clinically and pathologically indistinguishable from typical PD.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B17G</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002B17A03</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Parkinson maladie</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Parkinson disease</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Parkinson enfermedad</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Mutation</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Mutation</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Mutación</s0>
<s5>09</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fN21><s1>085</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001530 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Curation/biblio.hfd -nk 001530 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    PascalFrancis
   |étape=   Curation
   |type=    RBID
   |clé=     Pascal:07-0133261
   |texte=   Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation
}}

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation

Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371val mutation

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri