Age at menopause predicts age at onset of Parkinson's disease
Identifieur interne : 001463 ( PascalFrancis/Curation ); précédent : 001462; suivant : 001464Age at menopause predicts age at onset of Parkinson's disease
Auteurs : Paolo Ragonese [Italie] ; Marco D'Amelio [Italie] ; Graziella Callari [Italie] ; Giuseppe Salemi [Italie] ; Letterio Morgante [Italie] ; Giovanni Savettieri [Italie]Source :
- Movement disorders [ 0885-3185 ] ; 2006.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
Abstract
We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.
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<front><div type="abstract" xml:lang="en">We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.</div>
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