Movement Disorders (revue)

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New developments of brain imaging for Parkinson's disease and related disorders

Identifieur interne : 001433 ( PascalFrancis/Curation ); précédent : 001432; suivant : 001434

New developments of brain imaging for Parkinson's disease and related disorders

Auteurs : Paola Piccini [Royaume-Uni] ; David J. Brooks [Royaume-Uni]

Source :

RBID : Pascal:07-0090851

Descripteurs français

English descriptors

Abstract

Parkinson's disease (PD) and related disorders are subcortical degenerations targeting the nigrostriatal dopaminergic system and basal ganglia. Traditionally, MRI has been used to detect structural and positron emission tomography and single emission computed tomography functional neurochemical and metabolic changes associated with these disorders. Recently, advances in diffusion-weighted MRI, ultrasonography, and radiotracer-based imaging have yielded greater sensitivity for revealing structural change and allowed detection of changes in brain dopamine levels after levodopa and during behavioral tasks. This review focuses on these recent advances in neuroimaging technology and their use for the diagnosis and assessment of PD and other parkinsonian disorders.
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A11 01  1    @1 PICCINI (Paola)
A11 02  1    @1 BROOKS (David J.)
A14 01      @1 MRC Clinical Sciences Centre and Division of Neuroscience and Mental Health, Imperial College, Hammersmith Hospital @2 London @3 GBR @Z 1 aut. @Z 2 aut.
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A44       @0 0000 @1 © 2007 INIST-CNRS. All rights reserved.
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C01 01    ENG  @0 Parkinson's disease (PD) and related disorders are subcortical degenerations targeting the nigrostriatal dopaminergic system and basal ganglia. Traditionally, MRI has been used to detect structural and positron emission tomography and single emission computed tomography functional neurochemical and metabolic changes associated with these disorders. Recently, advances in diffusion-weighted MRI, ultrasonography, and radiotracer-based imaging have yielded greater sensitivity for revealing structural change and allowed detection of changes in brain dopamine levels after levodopa and during behavioral tasks. This review focuses on these recent advances in neuroimaging technology and their use for the diagnosis and assessment of PD and other parkinsonian disorders.
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C03 04  X  ENG  @0 Functional imaging @5 09
C03 04  X  SPA  @0 Imaginería funcional @5 09
C07 01  X  FRE  @0 Système nerveux central pathologie @5 37
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C07 01  X  SPA  @0 Sistema nervosio central patología @5 37
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C07 03  X  FRE  @0 Maladie dégénérative @5 39
C07 03  X  ENG  @0 Degenerative disease @5 39
C07 03  X  SPA  @0 Enfermedad degenerativa @5 39
N21       @1 057
N44 01      @1 OTO
N82       @1 OTO

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Pascal:07-0090851

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