MovDisordV3, PascalFrancis, Curation, bibRecord, 001050

A blessing in disguise : Resolution of tardive dyskinesia with development of cervical myelitis

Identifieur interne : 001050 ( PascalFrancis/Curation ); précédent : 001049; suivant : 001051

A blessing in disguise : Resolution of tardive dyskinesia with development of cervical myelitis

Auteurs : Erie Chuen-Hian Lim [Singapour] ; Einar P. V. Wilder-Smith [Singapour] ; Raymond Chee-Seong Seet [Singapour]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:06-0135511

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Dyskinésie, Myélite.

English descriptors

KwdEn :
- Dyskinesia, Myelitis, Nervous system diseases.

Abstract

Tardive dyskinesia (TD), which is frequently seen in patients treated with dopamine receptor blocking agents, is difficult to manage. We report on a young Chinese man with bipolar disorder who developed TD after haloperidol treatment, involving the trunk, limbs, and orofacial area. TD persisted despite switching to atypical antipsychotic agents and treatment with valproate, benzodiazepines, and tetrabenazine. Resolution only occurred years later when he developed quadriplegia arising from infective myelitis of the cervical cord (C4-5). He had concomitant vertebral osteomyelitis, which was successfully treated with intravenous antibiotics. With intensive rehabilitation, he recovered the use of his limbs, but had no recurrence of TD. We attribute the resolution of orofacial dyskinesias with a cervical lesion to the interconnections between the orofacial area and cervical spine via the trigeminal nucleus (which has fibers descending as far caudally as C6), as well as to resetting of cortical maps.

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A11	`01`	`1`		`@1 LIM (Erie Chuen-Hian)`
A11	`02`	`1`		`@1 WILDER-SMITH (Einar P. V.)`
A11	`03`	`1`		`@1 SEET (Raymond Chee-Seong)`
A14	`01`			`@1 Division of Neurology, National University Hospital @3 SGP @Z 1 aut. @Z 2 aut. @Z 3 aut.`
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C01	`01`		`ENG`	@0 Tardive dyskinesia (TD), which is frequently seen in patients treated with dopamine receptor blocking agents, is difficult to manage. We report on a young Chinese man with bipolar disorder who developed TD after haloperidol treatment, involving the trunk, limbs, and orofacial area. TD persisted despite switching to atypical antipsychotic agents and treatment with valproate, benzodiazepines, and tetrabenazine. Resolution only occurred years later when he developed quadriplegia arising from infective myelitis of the cervical cord (C4-5). He had concomitant vertebral osteomyelitis, which was successfully treated with intravenous antibiotics. With intensive rehabilitation, he recovered the use of his limbs, but had no recurrence of TD. We attribute the resolution of orofacial dyskinesias with a cervical lesion to the interconnections between the orofacial area and cervical spine via the trigeminal nucleus (which has fibers descending as far caudally as C6), as well as to resetting of cortical maps.
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C03	`02`	`X`	`FRE`	`@0 Dyskinésie @5 02`
C03	`02`	`X`	`ENG`	`@0 Dyskinesia @5 02`
C03	`02`	`X`	`SPA`	`@0 Disquinesia @5 02`
C03	`03`	`X`	`FRE`	`@0 Myélite @5 03`
C03	`03`	`X`	`ENG`	`@0 Myelitis @5 03`
C03	`03`	`X`	`SPA`	`@0 Mielitis @5 03`
C07	`01`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 37`
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C07	`01`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 37`
C07	`02`	`X`	`FRE`	`@0 Mouvement involontaire @5 38`
C07	`02`	`X`	`ENG`	`@0 Involuntary movement @5 38`
C07	`02`	`X`	`SPA`	`@0 Movimiento involuntario @5 38`
C07	`03`	`X`	`FRE`	`@0 Trouble neurologique @5 39`
C07	`03`	`X`	`ENG`	`@0 Neurological disorder @5 39`
C07	`03`	`X`	`SPA`	`@0 Trastorno neurológico @5 39`
C07	`04`	`X`	`FRE`	`@0 Encéphale pathologie @5 40`
C07	`04`	`X`	`ENG`	`@0 Cerebral disorder @5 40`
C07	`04`	`X`	`SPA`	`@0 Encéfalo patología @5 40`
C07	`05`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 41`
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C07	`05`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 41`
N21				`@1 086`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

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Pascal:06-0135511

Le document en format XML

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	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

A blessing in disguise : Resolution of tardive dyskinesia with development of cervical myelitis

A blessing in disguise : Resolution of tardive dyskinesia with development of cervical myelitis

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri