Treatment of dementia with lewy bodies and Parkinson's disease dementia
Identifieur interne :
000F48 ( PascalFrancis/Curation );
précédent :
000F47;
suivant :
000F49
Treatment of dementia with lewy bodies and Parkinson's disease dementia
Auteurs : Werner Poewe [
Autriche]
Source :
-
Movement disorders [ 0885-3185 ] ; 2005.
RBID : Pascal:05-0457542
Descripteurs français
English descriptors
Abstract
Cognitive decline and dementia affect approximately 30% to 40% of patients with idiopathic Parkinson's disease during the course of their illness. PD-dementia (PDD) and dementia with Lewy bodies (DLB) are second to Alzheimer's disease in causing degenerative dementia in the elderly. The nosological distinction of the conditions has remained controversial because of broad clinical and pathological overlap. Treatment issues in both clinical settings are virtually identical. Treatment of Parkinsonism is often complicated by drug-induced psychosis and reduced levodopa responsiveness. Cognition, alertness, attention, as well as apathy or aggressive behavior have been shown to respond to treatment with cholinesterase inhibitors in randomized controlled trials both in DLB and PDD. Such treatment may also improve hallucinosis, but many patients will require add-on treatment with atypical neuroleptics to control drug-induced psychotic reactions. Clozapine and quetiapine are the drugs most commonly used and, contrary to classic neuroleptics, risperidone or olanzapine do not seem to cause severe side effects according to published data.
pA |
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A03 | | 1 | | @0 Mov. disord. |
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A05 | | | | @2 20 |
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A06 | | | | @3 SUP12 |
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A08 | 01 | 1 | ENG | @1 Treatment of dementia with lewy bodies and Parkinson's disease dementia |
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A09 | 01 | 1 | ENG | @1 Atypical Parkinsonian Disorders |
---|
A11 | 01 | 1 | | @1 POEWE (Werner) |
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A12 | 01 | 1 | | @1 POEWE (Werner) @9 ed. |
---|
A12 | 02 | 1 | | @1 WENNING (Gregor K.) @9 ed. |
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A14 | 01 | | | @1 Department of Neurology, Medical University of Innsbruck @3 AUT @Z 1 aut. |
---|
A15 | 01 | | | @1 Department of Neurology, Medical University Innsbruck @2 Innsbruck @3 AUT @Z 1 aut. @Z 2 aut. |
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A21 | | | | @1 2005 |
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A43 | 01 | | | @1 INIST @2 20953 @5 354000132714250120 |
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C01 | 01 | | ENG | @0 Cognitive decline and dementia affect approximately 30% to 40% of patients with idiopathic Parkinson's disease during the course of their illness. PD-dementia (PDD) and dementia with Lewy bodies (DLB) are second to Alzheimer's disease in causing degenerative dementia in the elderly. The nosological distinction of the conditions has remained controversial because of broad clinical and pathological overlap. Treatment issues in both clinical settings are virtually identical. Treatment of Parkinsonism is often complicated by drug-induced psychosis and reduced levodopa responsiveness. Cognition, alertness, attention, as well as apathy or aggressive behavior have been shown to respond to treatment with cholinesterase inhibitors in randomized controlled trials both in DLB and PDD. Such treatment may also improve hallucinosis, but many patients will require add-on treatment with atypical neuroleptics to control drug-induced psychotic reactions. Clozapine and quetiapine are the drugs most commonly used and, contrary to classic neuroleptics, risperidone or olanzapine do not seem to cause severe side effects according to published data. |
---|
C02 | 01 | X | | @0 002B17 |
---|
C02 | 02 | X | | @0 002B17G |
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C03 | 01 | X | ENG | @0 Nervous system diseases @5 01 |
---|
C03 | 01 | X | SPA | @0 Sistema nervioso patología @5 01 |
---|
C03 | 02 | X | FRE | @0 Parkinson maladie @5 02 |
---|
C03 | 02 | X | ENG | @0 Parkinson disease @5 02 |
---|
C03 | 02 | X | SPA | @0 Parkinson enfermedad @5 02 |
---|
C03 | 03 | X | FRE | @0 Traitement @5 09 |
---|
C03 | 03 | X | ENG | @0 Treatment @5 09 |
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C03 | 03 | X | SPA | @0 Tratamiento @5 09 |
---|
C03 | 04 | X | FRE | @0 Démence corps Lewy @2 NM @5 10 |
---|
C03 | 04 | X | ENG | @0 Lewy body dementia @2 NM @5 10 |
---|
C03 | 04 | X | SPA | @0 Demencia cuerpos Lewy @2 NM @5 10 |
---|
C03 | 05 | X | FRE | @0 Cholinesterase @2 FE @5 11 |
---|
C03 | 05 | X | ENG | @0 Cholinesterase @2 FE @5 11 |
---|
C03 | 05 | X | SPA | @0 Cholinesterase @2 FE @5 11 |
---|
C03 | 06 | X | FRE | @0 Antipsychotique @5 12 |
---|
C03 | 06 | X | ENG | @0 Antipsychotic @5 12 |
---|
C03 | 06 | X | SPA | @0 Antipsicótico @5 12 |
---|
C07 | 01 | X | FRE | @0 Carboxylic ester hydrolases @2 FE |
---|
C07 | 01 | X | ENG | @0 Carboxylic ester hydrolases @2 FE |
---|
C07 | 01 | X | SPA | @0 Carboxylic ester hydrolases @2 FE |
---|
C07 | 02 | X | FRE | @0 Esterases @2 FE |
---|
C07 | 02 | X | ENG | @0 Esterases @2 FE |
---|
C07 | 02 | X | SPA | @0 Esterases @2 FE |
---|
C07 | 03 | X | FRE | @0 Hydrolases @2 FE |
---|
C07 | 03 | X | ENG | @0 Hydrolases @2 FE |
---|
C07 | 03 | X | SPA | @0 Hydrolases @2 FE |
---|
C07 | 04 | X | FRE | @0 Enzyme @2 FE |
---|
C07 | 04 | X | ENG | @0 Enzyme @2 FE |
---|
C07 | 04 | X | SPA | @0 Enzima @2 FE |
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C07 | 05 | X | FRE | @0 Encéphale pathologie @5 37 |
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C07 | 05 | X | ENG | @0 Cerebral disorder @5 37 |
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C07 | 05 | X | SPA | @0 Encéfalo patología @5 37 |
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C07 | 06 | X | FRE | @0 Extrapyramidal syndrome @5 38 |
---|
C07 | 06 | X | ENG | @0 Extrapyramidal syndrome @5 38 |
---|
C07 | 06 | X | SPA | @0 Extrapiramidal síndrome @5 38 |
---|
C07 | 07 | X | FRE | @0 Maladie dégénérative @5 39 |
---|
C07 | 07 | X | ENG | @0 Degenerative disease @5 39 |
---|
C07 | 07 | X | SPA | @0 Enfermedad degenerativa @5 39 |
---|
C07 | 08 | X | FRE | @0 Système nerveux central pathologie @5 40 |
---|
C07 | 08 | X | ENG | @0 Central nervous system disease @5 40 |
---|
C07 | 08 | X | SPA | @0 Sistema nervosio central patología @5 40 |
---|
N21 | | | | @1 318 |
---|
N44 | 01 | | | @1 OTO |
---|
N82 | | | | @1 OTO |
---|
|
pR |
A30 | 01 | 1 | ENG | @1 Atypical Parkinsonian Disorders - From Protein Dysfunction to Therapeutic Intervention. International Meeting @3 Innsbruck AUT @4 2003-02-19 |
---|
|
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Pascal:05-0457542
Le document en format XML
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<front><div type="abstract" xml:lang="en">Cognitive decline and dementia affect approximately 30% to 40% of patients with idiopathic Parkinson's disease during the course of their illness. PD-dementia (PDD) and dementia with Lewy bodies (DLB) are second to Alzheimer's disease in causing degenerative dementia in the elderly. The nosological distinction of the conditions has remained controversial because of broad clinical and pathological overlap. Treatment issues in both clinical settings are virtually identical. Treatment of Parkinsonism is often complicated by drug-induced psychosis and reduced levodopa responsiveness. Cognition, alertness, attention, as well as apathy or aggressive behavior have been shown to respond to treatment with cholinesterase inhibitors in randomized controlled trials both in DLB and PDD. Such treatment may also improve hallucinosis, but many patients will require add-on treatment with atypical neuroleptics to control drug-induced psychotic reactions. Clozapine and quetiapine are the drugs most commonly used and, contrary to classic neuroleptics, risperidone or olanzapine do not seem to cause severe side effects according to published data.</div>
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