MovDisordV3, PascalFrancis, Curation, bibRecord, 000F15

Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy

Identifieur interne : 000F15 ( PascalFrancis/Curation ); précédent : 000F14; suivant : 000F16

Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy

Auteurs : Masataka Nishimura [Japon] ; Sadako Kuno [Japon] ; Ryuji Kaji [Japon] ; Hideshi Kawakami [Japon]

Source :

Movement disorders [ 0885-3185 ] ; 2005.

RBID : Pascal:05-0444032

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Démence Alzheimer, Parkinson maladie, Atrophie multisystématisée, Facteur BDNF, Polymorphisme, Japonais, Homme, Sporadique.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Alzheimer disease, Brain derived neurotrophic factor, Human, Japanese, Multiple system atrophy, Nervous system diseases, Parkinson disease, Polymorphism, Sporadic.

Abstract

We studied two genetic polymorphisms (240C/T and 480G/A) of the brain-derived neurotrophic factor (BDNF) gene in Japanese patients with Alzheimer's disease (AD, n = 172), Parkinson's disease (PD, n = 327), and multiple system atrophy (MSA, n = 122), as well as controls (n = 275). The distribution of the 240 C/T polymorphism was significantly different between AD patients and controls, whereas there was no difference in the genotype of the two polymorphisms between MSA and controls or between PD and controls. Our data suggest that BDNF might play a role in AD.

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A11	`04`	`1`		`@1 KAWAKAMI (Hideshi)`
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C01	`01`		`ENG`	@0 We studied two genetic polymorphisms (240C/T and 480G/A) of the brain-derived neurotrophic factor (BDNF) gene in Japanese patients with Alzheimer's disease (AD, n = 172), Parkinson's disease (PD, n = 327), and multiple system atrophy (MSA, n = 122), as well as controls (n = 275). The distribution of the 240 C/T polymorphism was significantly different between AD patients and controls, whereas there was no difference in the genotype of the two polymorphisms between MSA and controls or between PD and controls. Our data suggest that BDNF might play a role in AD.
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C03	`04`	`X`	`FRE`	`@0 Atrophie multisystématisée @2 NM @5 04`
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C03	`04`	`X`	`SPA`	`@0 Atrofia multisistematizada @2 NM @5 04`
C03	`05`	`X`	`FRE`	`@0 Facteur BDNF @5 09`
C03	`05`	`X`	`ENG`	`@0 Brain derived neurotrophic factor @5 09`
C03	`05`	`X`	`SPA`	`@0 Factor BDNF @5 09`
C03	`06`	`X`	`FRE`	`@0 Polymorphisme @5 10`
C03	`06`	`X`	`ENG`	`@0 Polymorphism @5 10`
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C03	`09`	`X`	`FRE`	`@0 Sporadique @5 13`
C03	`09`	`X`	`ENG`	`@0 Sporadic @5 13`
C03	`09`	`X`	`SPA`	`@0 Esporádico @5 13`
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<front><div type="abstract" xml:lang="en">We studied two genetic polymorphisms (240C/T and 480G/A) of the brain-derived neurotrophic factor (BDNF) gene in Japanese patients with Alzheimer's disease (AD, n = 172), Parkinson's disease (PD, n = 327), and multiple system atrophy (MSA, n = 122), as well as controls (n = 275). The distribution of the 240 C/T polymorphism was significantly different between AD patients and controls, whereas there was no difference in the genotype of the two polymorphisms between MSA and controls or between PD and controls. Our data suggest that BDNF might play a role in AD.</div>
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   |texte=   Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy
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	Movement Disorders (revue)
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Movement Disorders (revue)

Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy

Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy

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