MovDisordV3, PascalFrancis, Curation, bibRecord, 000D80

Staging disease severity in movement disorder tauopathies: Brain atrophy separates progressive supranuclear palsy from corticobasal degeneration

Identifieur interne : 000D80 ( PascalFrancis/Curation ); précédent : 000D79; suivant : 000D81

Staging disease severity in movement disorder tauopathies: Brain atrophy separates progressive supranuclear palsy from corticobasal degeneration

Auteurs : Emma C. Schofield [Australie] ; Diana Caine [Australie] ; Jillian J. Kril [Australie] ; Nicholas J. Cordato [Australie] ; Glenda M. Halliday [Australie]

Source :

Movement disorders [ 0885-3185 ] ; 2005.

RBID : Pascal:05-0173684

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Encéphale, Atrophie, Dégénérescence.

English descriptors

KwdEn :
- Atrophy, Degeneration, Encephalon, Nervous system diseases.

Abstract

The movement disorders progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) both deposit tau in degenerating neurons and are considered to be tauopathies. The recently developed scheme for staging tissue degeneration in another tauopathy, frontotemporal dementia [Broe et al., Neurology 2003;60:1005-1011] was applied to pathologically confirmed PSP (n = 24) and CBD (n = 9) cases and correlated with clinical indices. In contrast to frontotemporal dementia, the majority of PSP cases had limited or no visible atrophy, while the pattern of atrophy in CBD cases conformed to the existing staging scheme (all but one case exhibiting substantial visible tissue atrophy). Despite similar clinical severity and disease duration between groups, there was a marked difference between the PSP and CBD cases in pathological disease stage (X² = 8.86; P = 0.03). The degree of global atrophy in PSP appears to be distinct from other tauopathies, while CBD fits the same pattern as other pathological forms of frontotemporal dementia.

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C03	`02`	`X`	`FRE`	`@0 Encéphale @5 02`
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C03	`02`	`X`	`SPA`	`@0 Encéfalo @5 02`
C03	`03`	`X`	`FRE`	`@0 Atrophie @5 04`
C03	`03`	`X`	`ENG`	`@0 Atrophy @5 04`
C03	`03`	`X`	`SPA`	`@0 Atrofia @5 04`
C03	`04`	`X`	`FRE`	`@0 Dégénérescence @5 07`
C03	`04`	`X`	`ENG`	`@0 Degeneration @5 07`
C03	`04`	`X`	`SPA`	`@0 Degeneración @5 07`
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C07	`01`	`X`	`ENG`	`@0 Central nervous system @5 37`
C07	`01`	`X`	`SPA`	`@0 Sistema nervioso central @5 37`
N21				`@1 115`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

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Le document en format XML

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	Movement Disorders (revue)
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Movement Disorders (revue)

Staging disease severity in movement disorder tauopathies: Brain atrophy separates progressive supranuclear palsy from corticobasal degeneration

Staging disease severity in movement disorder tauopathies: Brain atrophy separates progressive supranuclear palsy from corticobasal degeneration

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri