MovDisordV3, PascalFrancis, Curation, bibRecord, 000C98

Dopamine receptor gene polymorphisms in Parkinson's disease patients reporting "sleep attacks"

Identifieur interne : 000C98 ( PascalFrancis/Curation ); précédent : 000C97; suivant : 000C99

Dopamine receptor gene polymorphisms in Parkinson's disease patients reporting "sleep attacks"

Auteurs : Ida Rissling [Allemagne] ; Frank Geller [Allemagne] ; Oliver Bandmann [Allemagne] ; Karim Stiasny-Kolster [Allemagne] ; Yvonne Körner [Allemagne] ; Charlotte Meindorfner [Allemagne] ; Hans-Peter Krüger [Allemagne] ; Wolfgang H. Oertel [Allemagne] ; J. Carsten Möller [Allemagne]

Source :

Movement disorders [ 0885-3185 ] ; 2004.

RBID : Pascal:05-0001307

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Récepteur dopaminergique, Polymorphisme, Parkinson maladie, Homme, Sommeil.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Dopamine receptor, Human, Nervous system diseases, Parkinson disease, Polymorphism, Sleep.

Abstract

Genes encoding proteins involved in dopaminergic transmission are potential candidate genes for the induction of somnolence in Parkinson's disease (PD) because dopaminergic agents have been shown to be associated with sudden onset of sleep (SOS) in PD. We conducted an association study on dopamine D2, D3, and D4 receptor gene polymorphisms comparing 137 PD patients with SOS and 137 PD patients without SOS matched according to drug therapy, disease duration, sex, and age. Our results show a significant association between the dopamine D2 receptor gene polymorphism Taq IA and SOS in PD. No significant association between two other investigated polymorphisms and the phenomenon of "sleep attacks" in PD was observed.

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A11	`03`	`1`		`@1 BANDMANN (Oliver)`
A11	`04`	`1`		`@1 STIASNY-KOLSTER (Karim)`
A11	`05`	`1`		`@1 KÖRNER (Yvonne)`
A11	`06`	`1`		`@1 MEINDORFNER (Charlotte)`
A11	`07`	`1`		`@1 KRÜGER (Hans-Peter)`
A11	`08`	`1`		`@1 OERTEL (Wolfgang H.)`
A11	`09`	`1`		`@1 MÖLLER (J. Carsten)`
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C03	`02`	`X`	`FRE`	`@0 Récepteur dopaminergique @5 02`
C03	`02`	`X`	`ENG`	`@0 Dopamine receptor @5 02`
C03	`02`	`X`	`SPA`	`@0 Receptor dopaminérgico @5 02`
C03	`03`	`X`	`FRE`	`@0 Polymorphisme @5 03`
C03	`03`	`X`	`ENG`	`@0 Polymorphism @5 03`
C03	`03`	`X`	`SPA`	`@0 Polimorfismo @5 03`
C03	`04`	`X`	`FRE`	`@0 Parkinson maladie @5 04`
C03	`04`	`X`	`ENG`	`@0 Parkinson disease @5 04`
C03	`04`	`X`	`SPA`	`@0 Parkinson enfermedad @5 04`
C03	`05`	`X`	`FRE`	`@0 Homme @5 05`
C03	`05`	`X`	`ENG`	`@0 Human @5 05`
C03	`05`	`X`	`SPA`	`@0 Hombre @5 05`
C03	`06`	`X`	`FRE`	`@0 Sommeil @5 06`
C03	`06`	`X`	`ENG`	`@0 Sleep @5 06`
C03	`06`	`X`	`SPA`	`@0 Sueño @5 06`
C07	`01`	`X`	`FRE`	`@0 Encéphale pathologie @5 37`
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C07	`02`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 38`
C07	`03`	`X`	`FRE`	`@0 Maladie dégénérative @5 39`
C07	`03`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
C07	`04`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 40`
C07	`04`	`X`	`ENG`	`@0 Central nervous system disease @5 40`
C07	`04`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 40`
C07	`05`	`X`	`FRE`	`@0 Cycle veille sommeil @5 41`
C07	`05`	`X`	`ENG`	`@0 Sleep wake cycle @5 41`
C07	`05`	`X`	`SPA`	`@0 Ciclo sueño vigilia @5 41`
N21				`@1 004`
N44	`01`			`@1 OTO`
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Pascal:05-0001307

Le document en format XML

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<front><div type="abstract" xml:lang="en">Genes encoding proteins involved in dopaminergic transmission are potential candidate genes for the induction of somnolence in Parkinson's disease (PD) because dopaminergic agents have been shown to be associated with sudden onset of sleep (SOS) in PD. We conducted an association study on dopamine D2, D3, and D4 receptor gene polymorphisms comparing 137 PD patients with SOS and 137 PD patients without SOS matched according to drug therapy, disease duration, sex, and age. Our results show a significant association between the dopamine D2 receptor gene polymorphism Taq IA and SOS in PD. No significant association between two other investigated polymorphisms and the phenomenon of "sleep attacks" in PD was observed.</div>
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<fC03 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Récepteur dopaminergique</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Dopamine receptor</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Receptor dopaminérgico</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Polymorphisme</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Polymorphism</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Polimorfismo</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Parkinson maladie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Parkinson disease</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Parkinson enfermedad</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Homme</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Human</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Hombre</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Sommeil</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Sleep</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Sueño</s0>
<s5>06</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Cycle veille sommeil</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Sleep wake cycle</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Ciclo sueño vigilia</s0>
<s5>41</s5>
</fC07>
<fN21><s1>004</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Dopamine receptor gene polymorphisms in Parkinson's disease patients reporting "sleep attacks"

Dopamine receptor gene polymorphisms in Parkinson's disease patients reporting "sleep attacks"

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