MovDisordV3, PascalFrancis, Curation, bibRecord, 000388

Treatment of dystonic clenched fist with botulinum toxin

Identifieur interne : 000388 ( PascalFrancis/Curation ); précédent : 000387; suivant : 000389

Treatment of dystonic clenched fist with botulinum toxin

Auteurs : Carla Cordivari [Royaume-Uni] ; V. Peter Misra [Royaume-Uni] ; Santiago Catania [Royaume-Uni] ; Andrew J. Lees [Royaume-Uni]

Source :

Movement disorders [ 0885-3185 ] ; 2001.

RBID : Pascal:02-0049773

Descripteurs français

Pascal (Inist)
- Dystonie, Douleur régionale complexe syndrome, Toxine, Botulisme, Chimiothérapie, Myorelaxant, Spasmolytique, Dégénérescence, Cortex cérébral, Noyau gris central, Traitement, Complication, Personne âgée.
Wicri :
- topic : Personne âgée.

English descriptors

KwdEn :
- Antispasmodic agent, Basal ganglion, Botulism, Cerebral cortex, Chemotherapy, Complex regional pain syndrome, Complication, Degeneration, Dystonia, Elderly, Muscle relaxant, Toxin, Treatment.

Abstract

Fourteen patients with "dystonic clenched fist" (three with Corticobasal Ganglionic Degeneration, seven with Parkinson's disease, and four with Dystonic-Complex Regional Pain Syndrome) were treated with botulinum toxin A (BTXA, Dysport®). The muscles involved were identified by the hand posture and EMG activity recorded at rest and during active and passive flexion/extension movements of the finger and wrist. EMG was useful in distinguishing between muscle contraction and underlying contractures and to determine the dosage of BTX. All patients had some degree of flexion at the proximal metacarpophalangeal joints and required injections into the lumbricals. The response in patients depended on the severity of the deformity and the degree of contracture. All patients had significant benefit to pain, with accompanying muscle relaxation, and palmar infection, when present, was eradicated. Four patients with Parkinson's disease and one patient with Dystonia-Complex Regional Pain Syndrome obtained functional benefit.

A01	`01`	`1`		`@0 0885-3185`
A03		`1`		`@0 Mov. disord.`
A05				`@2 16`
A06				`@2 5`
A08	`01`	`1`	`ENG`	`@1 Treatment of dystonic clenched fist with botulinum toxin`
A11	`01`	`1`		`@1 CORDIVARI (Carla)`
A11	`02`	`1`		`@1 MISRA (V. Peter)`
A11	`03`	`1`		`@1 CATANIA (Santiago)`
A11	`04`	`1`		`@1 LEES (Andrew J.)`
A14	`01`			`@1 Department of Clinical Neurophysiology, The National Hospital for Neurology and Neurosurgery, Queen Square @2 London @3 GBR @Z 1 aut. @Z 2 aut. @Z 3 aut.`
A14	`02`			`@1 Reta Lila Weston Institute of Neurological Studies, University College of London @3 GBR @Z 1 aut. @Z 4 aut.`
A20				`@1 907-913`
A21				`@1 2001`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000099256460140`
A44				`@0 0000 @1 © 2002 INIST-CNRS. All rights reserved.`
A45				`@0 24 ref.`
A47	`01`	`1`		`@0 02-0049773`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Fourteen patients with "dystonic clenched fist" (three with Corticobasal Ganglionic Degeneration, seven with Parkinson's disease, and four with Dystonic-Complex Regional Pain Syndrome) were treated with botulinum toxin A (BTXA, Dysport®). The muscles involved were identified by the hand posture and EMG activity recorded at rest and during active and passive flexion/extension movements of the finger and wrist. EMG was useful in distinguishing between muscle contraction and underlying contractures and to determine the dosage of BTX. All patients had some degree of flexion at the proximal metacarpophalangeal joints and required injections into the lumbricals. The response in patients depended on the severity of the deformity and the degree of contracture. All patients had significant benefit to pain, with accompanying muscle relaxation, and palmar infection, when present, was eradicated. Four patients with Parkinson's disease and one patient with Dystonia-Complex Regional Pain Syndrome obtained functional benefit.
C02	`01`	`X`		`@0 002B02C`
C03	`01`	`X`	`FRE`	`@0 Dystonie @5 01`
C03	`01`	`X`	`ENG`	`@0 Dystonia @5 01`
C03	`01`	`X`	`SPA`	`@0 Distonía @5 01`
C03	`02`	`X`	`FRE`	`@0 Douleur régionale complexe syndrome @2 NM @5 02`
C03	`02`	`X`	`ENG`	`@0 Complex regional pain syndrome @2 NM @5 02`
C03	`02`	`X`	`SPA`	`@0 Dolor regional complejo síndrome @2 NM @5 02`
C03	`03`	`X`	`FRE`	`@0 Toxine @5 04`
C03	`03`	`X`	`ENG`	`@0 Toxin @5 04`
C03	`03`	`X`	`SPA`	`@0 Toxina @5 04`
C03	`04`	`X`	`FRE`	`@0 Botulisme @5 05`
C03	`04`	`X`	`ENG`	`@0 Botulism @5 05`
C03	`04`	`X`	`SPA`	`@0 Botulismo @5 05`
C03	`05`	`X`	`FRE`	`@0 Chimiothérapie @5 06`
C03	`05`	`X`	`ENG`	`@0 Chemotherapy @5 06`
C03	`05`	`X`	`SPA`	`@0 Quimioterapia @5 06`
C03	`06`	`X`	`FRE`	`@0 Myorelaxant @5 07`
C03	`06`	`X`	`ENG`	`@0 Muscle relaxant @5 07`
C03	`06`	`X`	`SPA`	`@0 Relajante muscular @5 07`
C03	`07`	`X`	`FRE`	`@0 Spasmolytique @5 08`
C03	`07`	`X`	`ENG`	`@0 Antispasmodic agent @5 08`
C03	`07`	`X`	`SPA`	`@0 Espasmolítico @5 08`
C03	`08`	`X`	`FRE`	`@0 Dégénérescence @5 10`
C03	`08`	`X`	`ENG`	`@0 Degeneration @5 10`
C03	`08`	`X`	`SPA`	`@0 Degeneración @5 10`
C03	`09`	`X`	`FRE`	`@0 Cortex cérébral @5 11`
C03	`09`	`X`	`ENG`	`@0 Cerebral cortex @5 11`
C03	`09`	`X`	`SPA`	`@0 Corteza cerebral @5 11`
C03	`10`	`X`	`FRE`	`@0 Noyau gris central @5 12`
C03	`10`	`X`	`ENG`	`@0 Basal ganglion @5 12`
C03	`10`	`X`	`SPA`	`@0 Núcleo basal @5 12`
C03	`11`	`X`	`FRE`	`@0 Traitement @5 17`
C03	`11`	`X`	`ENG`	`@0 Treatment @5 17`
C03	`11`	`X`	`SPA`	`@0 Tratamiento @5 17`
C03	`12`	`X`	`FRE`	`@0 Complication @5 18`
C03	`12`	`X`	`ENG`	`@0 Complication @5 18`
C03	`12`	`X`	`SPA`	`@0 Complicación @5 18`
C03	`13`	`X`	`FRE`	`@0 Personne âgée @5 20`
C03	`13`	`X`	`ENG`	`@0 Elderly @5 20`
C03	`13`	`X`	`SPA`	`@0 Anciano @5 20`
C07	`01`	`X`	`FRE`	`@0 Bactériose`
C07	`01`	`X`	`ENG`	`@0 Bacteriosis`
C07	`01`	`X`	`SPA`	`@0 Bacteriosis`
C07	`02`	`X`	`FRE`	`@0 Infection`
C07	`02`	`X`	`ENG`	`@0 Infection`
C07	`02`	`X`	`SPA`	`@0 Infección`
C07	`03`	`X`	`FRE`	`@0 Homme`
C07	`03`	`X`	`ENG`	`@0 Human`
C07	`03`	`X`	`SPA`	`@0 Hombre`
C07	`04`	`X`	`FRE`	`@0 Muscle strié pathologie @5 37`
C07	`04`	`X`	`ENG`	`@0 Striated muscle disease @5 37`
C07	`04`	`X`	`SPA`	`@0 Músculo estriado patología @5 37`
C07	`05`	`X`	`FRE`	`@0 Système nerveux pathologie @5 38`
C07	`05`	`X`	`ENG`	`@0 Nervous system diseases @5 38`
C07	`05`	`X`	`SPA`	`@0 Sistema nervioso patología @5 38`
C07	`06`	`X`	`FRE`	`@0 Trouble neurologique @5 39`
C07	`06`	`X`	`ENG`	`@0 Neurological disorder @5 39`
C07	`06`	`X`	`SPA`	`@0 Trastorno neurológico @5 39`
C07	`07`	`X`	`FRE`	`@0 Mouvement involontaire @5 40`
C07	`07`	`X`	`ENG`	`@0 Involuntary movement @5 40`
C07	`07`	`X`	`SPA`	`@0 Movimiento involuntario @5 40`
C07	`08`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 41`
C07	`08`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 41`
C07	`08`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 41`
C07	`09`	`X`	`FRE`	`@0 Système nerveux autonome pathologie @5 42`
C07	`09`	`X`	`ENG`	`@0 Diseases of the autonomic nervous system @5 42`
C07	`09`	`X`	`SPA`	`@0 Sistema nervioso autónomo patología @5 42`
C07	`10`	`X`	`FRE`	`@0 Maladie dégénérative @5 61`
C07	`10`	`X`	`ENG`	`@0 Degenerative disease @5 61`
C07	`10`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 61`
C07	`11`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 62`
C07	`11`	`X`	`ENG`	`@0 Central nervous system disease @5 62`
C07	`11`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 62`
C07	`12`	`X`	`FRE`	`@0 Encéphale pathologie @5 63`
C07	`12`	`X`	`ENG`	`@0 Cerebral disorder @5 63`
C07	`12`	`X`	`SPA`	`@0 Encéfalo patología @5 63`
N21				`@1 021`

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Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Treatment of dystonic clenched fist with botulinum toxin</title>
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<author><name sortKey="Misra, V Peter" sort="Misra, V Peter" uniqKey="Misra V" first="V. Peter" last="Misra">V. Peter Misra</name>
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<author><name sortKey="Catania, Santiago" sort="Catania, Santiago" uniqKey="Catania S" first="Santiago" last="Catania">Santiago Catania</name>
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<author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew J. Lees</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antispasmodic agent</term>
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<term>Chemotherapy</term>
<term>Complex regional pain syndrome</term>
<term>Complication</term>
<term>Degeneration</term>
<term>Dystonia</term>
<term>Elderly</term>
<term>Muscle relaxant</term>
<term>Toxin</term>
<term>Treatment</term>
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<term>Myorelaxant</term>
<term>Spasmolytique</term>
<term>Dégénérescence</term>
<term>Cortex cérébral</term>
<term>Noyau gris central</term>
<term>Traitement</term>
<term>Complication</term>
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<front><div type="abstract" xml:lang="en">Fourteen patients with "dystonic clenched fist" (three with Corticobasal Ganglionic Degeneration, seven with Parkinson's disease, and four with Dystonic-Complex Regional Pain Syndrome) were treated with botulinum toxin A (BTXA, Dysport®). The muscles involved were identified by the hand posture and EMG activity recorded at rest and during active and passive flexion/extension movements of the finger and wrist. EMG was useful in distinguishing between muscle contraction and underlying contractures and to determine the dosage of BTX. All patients had some degree of flexion at the proximal metacarpophalangeal joints and required injections into the lumbricals. The response in patients depended on the severity of the deformity and the degree of contracture. All patients had significant benefit to pain, with accompanying muscle relaxation, and palmar infection, when present, was eradicated. Four patients with Parkinson's disease and one patient with Dystonia-Complex Regional Pain Syndrome obtained functional benefit.</div>
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</fA11>
<fA14 i1="01"><s1>Department of Clinical Neurophysiology, The National Hospital for Neurology and Neurosurgery, Queen Square</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Reta Lila Weston Institute of Neurological Studies, University College of London</s1>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
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<fC01 i1="01" l="ENG"><s0>Fourteen patients with "dystonic clenched fist" (three with Corticobasal Ganglionic Degeneration, seven with Parkinson's disease, and four with Dystonic-Complex Regional Pain Syndrome) were treated with botulinum toxin A (BTXA, Dysport®). The muscles involved were identified by the hand posture and EMG activity recorded at rest and during active and passive flexion/extension movements of the finger and wrist. EMG was useful in distinguishing between muscle contraction and underlying contractures and to determine the dosage of BTX. All patients had some degree of flexion at the proximal metacarpophalangeal joints and required injections into the lumbricals. The response in patients depended on the severity of the deformity and the degree of contracture. All patients had significant benefit to pain, with accompanying muscle relaxation, and palmar infection, when present, was eradicated. Four patients with Parkinson's disease and one patient with Dystonia-Complex Regional Pain Syndrome obtained functional benefit.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B02C</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Dystonie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Dystonia</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Distonía</s0>
<s5>01</s5>
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<fC03 i1="02" i2="X" l="FRE"><s0>Douleur régionale complexe syndrome</s0>
<s2>NM</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Complex regional pain syndrome</s0>
<s2>NM</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Dolor regional complejo síndrome</s0>
<s2>NM</s2>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Toxine</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Toxin</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Toxina</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Botulisme</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Botulism</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Botulismo</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Chimiothérapie</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Chemotherapy</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Quimioterapia</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Myorelaxant</s0>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Muscle relaxant</s0>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Relajante muscular</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Spasmolytique</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Antispasmodic agent</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Espasmolítico</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Dégénérescence</s0>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Degeneration</s0>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Degeneración</s0>
<s5>10</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Cortex cérébral</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Cerebral cortex</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Corteza cerebral</s0>
<s5>11</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Noyau gris central</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Basal ganglion</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Núcleo basal</s0>
<s5>12</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Traitement</s0>
<s5>17</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Treatment</s0>
<s5>17</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>17</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Complication</s0>
<s5>18</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Complication</s0>
<s5>18</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Complicación</s0>
<s5>18</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Personne âgée</s0>
<s5>20</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>Elderly</s0>
<s5>20</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA"><s0>Anciano</s0>
<s5>20</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Bactériose</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Bacteriosis</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Bacteriosis</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Muscle strié pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Striated muscle disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Músculo estriado patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Trouble neurologique</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Neurological disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Trastorno neurológico</s0>
<s5>39</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Mouvement involontaire</s0>
<s5>40</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Involuntary movement</s0>
<s5>40</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Movimiento involuntario</s0>
<s5>40</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Système nerveux autonome pathologie</s0>
<s5>42</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Diseases of the autonomic nervous system</s0>
<s5>42</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Sistema nervioso autónomo patología</s0>
<s5>42</s5>
</fC07>
<fC07 i1="10" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>61</s5>
</fC07>
<fC07 i1="10" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>61</s5>
</fC07>
<fC07 i1="10" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>61</s5>
</fC07>
<fC07 i1="11" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>62</s5>
</fC07>
<fC07 i1="11" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>62</s5>
</fC07>
<fC07 i1="11" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>62</s5>
</fC07>
<fC07 i1="12" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>63</s5>
</fC07>
<fC07 i1="12" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>63</s5>
</fC07>
<fC07 i1="12" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>63</s5>
</fC07>
<fN21><s1>021</s1>
</fN21>
</pA>
</standard>
</inist>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Treatment of dystonic clenched fist with botulinum toxin

Treatment of dystonic clenched fist with botulinum toxin

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