MovDisordV3, PascalFrancis, Curation, bibRecord, 000201

An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice

Identifieur interne : 000201 ( PascalFrancis/Curation ); précédent : 000200; suivant : 000202

An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice

Auteurs : Christopher Dromey [Canada] ; Rajeev Kumar [Canada] ; Anthony E. Lang [Canada] ; Andres M. Lozano [Canada]

Source :

Movement disorders [ 0885-3185 ] ; 2000.

RBID : Pascal:01-0015551

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Stimulus électrique, Noyau sousthalamique, Bilatéral, Parole, Analyse parole, Mesure acoustique, Voix parlée, Traitement instrumental, Evaluation performance, Adulte.
Wicri :
- topic : Adulte.

English descriptors

KwdEn :
- Acoustic measurement, Adult, Bilateral, Electrical stimulus, Instrumentation therapy, Parkinson disease, Performance evaluation, Speaking voice, Speech, Speech analysis, Subthalamic nucleus.

Abstract

Seven patients with Parkinson's disease were implanted with deep brain stimulators to provide chronic electrical stimulation to the subthalamic nucleus bilaterally. Acoustic recordings and neurologic assessments were undertaken before surgery in the medication-off and medication-on conditions and after surgery with and without electrical stimulation in the medication-off and medication-on conditions. The data showed significant improvements in limb motor performance in response to medication before surgery and when the subthalamic nucleus was stimulated after surgery. Six months after surgery, there were small but statistically significant increases in sound pressure level and fundamental frequency variability in response to stimulation in the medication-on condition. No other statistically significant speech changes were measured. These findings are consistent with several other studies that have reported disparity between limb and speech improvements after neurosurgical intervention for Parkinson's disease.

A01	`01`	`1`		`@0 0885-3185`
A03		`1`		`@0 Mov. disord.`
A05				`@2 15`
A06				`@2 6`
A08	`01`	`1`	`ENG`	`@1 An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice`
A11	`01`	`1`		`@1 DROMEY (Christopher)`
A11	`02`	`1`		`@1 KUMAR (Rajeev)`
A11	`03`	`1`		`@1 LANG (Anthony E.)`
A11	`04`	`1`		`@1 LOZANO (Andres M.)`
A14	`01`			`@1 Department of Speech-Language Pathology, Toronto Western Hospital @2 Toronto, Ontario @3 CAN @Z 1 aut.`
A14	`02`			`@1 Department of Speech-Language Pathology, Faculty of Medicine, The University of Toronto @2 Toronto, Ontario @3 CAN @Z 1 aut.`
A14	`03`			`@1 Division of Neurology, Faculty of Medicine, The University of Toronto @2 Toronto, Ontario @3 CAN @Z 2 aut. @Z 3 aut.`
A14	`04`			`@1 Department of Medicine, Toronto Western Hospital @2 Toronto, Ontario @3 CAN @Z 3 aut.`
A14	`05`			`@1 Department of Surgery, Toronto Western Hospital @2 Toronto, Ontario @3 CAN @Z 4 aut.`
A14	`06`			`@1 Division of Neurosurgery, Faculty of Medicine, The University of Toronto @2 Toronto, Ontario @3 CAN @Z 4 aut.`
A20				`@1 1132-1138`
A21				`@1 2000`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000092814950110`
A44				`@0 0000 @1 © 2001 INIST-CNRS. All rights reserved.`
A45				`@0 31 ref.`
A47	`01`	`1`		`@0 01-0015551`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Seven patients with Parkinson's disease were implanted with deep brain stimulators to provide chronic electrical stimulation to the subthalamic nucleus bilaterally. Acoustic recordings and neurologic assessments were undertaken before surgery in the medication-off and medication-on conditions and after surgery with and without electrical stimulation in the medication-off and medication-on conditions. The data showed significant improvements in limb motor performance in response to medication before surgery and when the subthalamic nucleus was stimulated after surgery. Six months after surgery, there were small but statistically significant increases in sound pressure level and fundamental frequency variability in response to stimulation in the medication-on condition. No other statistically significant speech changes were measured. These findings are consistent with several other studies that have reported disparity between limb and speech improvements after neurosurgical intervention for Parkinson's disease.
C02	`01`	`X`		`@0 002B26I`
C03	`01`	`X`	`FRE`	`@0 Parkinson maladie @5 01`
C03	`01`	`X`	`ENG`	`@0 Parkinson disease @5 01`
C03	`01`	`X`	`SPA`	`@0 Parkinson enfermedad @5 01`
C03	`02`	`X`	`FRE`	`@0 Stimulus électrique @5 04`
C03	`02`	`X`	`ENG`	`@0 Electrical stimulus @5 04`
C03	`02`	`X`	`SPA`	`@0 Estímulo eléctrico @5 04`
C03	`03`	`X`	`FRE`	`@0 Noyau sousthalamique @5 05`
C03	`03`	`X`	`ENG`	`@0 Subthalamic nucleus @5 05`
C03	`03`	`X`	`SPA`	`@0 Núcleo subtalámico @5 05`
C03	`04`	`X`	`FRE`	`@0 Bilatéral @5 06`
C03	`04`	`X`	`ENG`	`@0 Bilateral @5 06`
C03	`04`	`X`	`SPA`	`@0 Bilateral @5 06`
C03	`05`	`X`	`FRE`	`@0 Parole @5 07`
C03	`05`	`X`	`ENG`	`@0 Speech @5 07`
C03	`05`	`X`	`SPA`	`@0 Habla @5 07`
C03	`06`	`X`	`FRE`	`@0 Analyse parole @5 08`
C03	`06`	`X`	`ENG`	`@0 Speech analysis @5 08`
C03	`06`	`X`	`SPA`	`@0 Análisis palabra @5 08`
C03	`07`	`X`	`FRE`	`@0 Mesure acoustique @5 10`
C03	`07`	`X`	`ENG`	`@0 Acoustic measurement @5 10`
C03	`07`	`X`	`SPA`	`@0 Medida acústica @5 10`
C03	`08`	`X`	`FRE`	`@0 Voix parlée @5 11`
C03	`08`	`X`	`ENG`	`@0 Speaking voice @5 11`
C03	`08`	`X`	`SPA`	`@0 Voz hablada @5 11`
C03	`09`	`X`	`FRE`	`@0 Traitement instrumental @5 17`
C03	`09`	`X`	`ENG`	`@0 Instrumentation therapy @5 17`
C03	`09`	`X`	`SPA`	`@0 Tratamiento instrumental @5 17`
C03	`10`	`X`	`FRE`	`@0 Evaluation performance @5 18`
C03	`10`	`X`	`ENG`	`@0 Performance evaluation @5 18`
C03	`10`	`X`	`SPA`	`@0 Evaluación prestación @5 18`
C03	`11`	`X`	`FRE`	`@0 Adulte @5 20`
C03	`11`	`X`	`ENG`	`@0 Adult @5 20`
C03	`11`	`X`	`SPA`	`@0 Adulto @5 20`
C07	`01`	`X`	`FRE`	`@0 Homme`
C07	`01`	`X`	`ENG`	`@0 Human`
C07	`01`	`X`	`SPA`	`@0 Hombre`
C07	`02`	`X`	`FRE`	`@0 Système nerveux pathologie @5 37`
C07	`02`	`X`	`ENG`	`@0 Nervous system diseases @5 37`
C07	`02`	`X`	`SPA`	`@0 Sistema nervioso patología @5 37`
C07	`03`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 38`
C07	`03`	`X`	`ENG`	`@0 Central nervous system disease @5 38`
C07	`03`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 38`
C07	`04`	`X`	`FRE`	`@0 Encéphale pathologie @5 39`
C07	`04`	`X`	`ENG`	`@0 Cerebral disorder @5 39`
C07	`04`	`X`	`SPA`	`@0 Encéfalo patología @5 39`
C07	`05`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 40`
C07	`05`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 40`
C07	`05`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 40`
C07	`06`	`X`	`FRE`	`@0 Maladie dégénérative @5 41`
C07	`06`	`X`	`ENG`	`@0 Degenerative disease @5 41`
C07	`06`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 41`
C07	`07`	`X`	`FRE`	`@0 Stimulation instrumentale @5 45`
C07	`07`	`X`	`ENG`	`@0 Instrumental stimulation @5 45`
C07	`07`	`X`	`SPA`	`@0 Estimulación instrumental @5 45`
N21				`@1 008`

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Pascal:01-0015551

Le document en format XML

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<front><div type="abstract" xml:lang="en">Seven patients with Parkinson's disease were implanted with deep brain stimulators to provide chronic electrical stimulation to the subthalamic nucleus bilaterally. Acoustic recordings and neurologic assessments were undertaken before surgery in the medication-off and medication-on conditions and after surgery with and without electrical stimulation in the medication-off and medication-on conditions. The data showed significant improvements in limb motor performance in response to medication before surgery and when the subthalamic nucleus was stimulated after surgery. Six months after surgery, there were small but statistically significant increases in sound pressure level and fundamental frequency variability in response to stimulation in the medication-on condition. No other statistically significant speech changes were measured. These findings are consistent with several other studies that have reported disparity between limb and speech improvements after neurosurgical intervention for Parkinson's disease.</div>
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<fC01 i1="01" l="ENG"><s0>Seven patients with Parkinson's disease were implanted with deep brain stimulators to provide chronic electrical stimulation to the subthalamic nucleus bilaterally. Acoustic recordings and neurologic assessments were undertaken before surgery in the medication-off and medication-on conditions and after surgery with and without electrical stimulation in the medication-off and medication-on conditions. The data showed significant improvements in limb motor performance in response to medication before surgery and when the subthalamic nucleus was stimulated after surgery. Six months after surgery, there were small but statistically significant increases in sound pressure level and fundamental frequency variability in response to stimulation in the medication-on condition. No other statistically significant speech changes were measured. These findings are consistent with several other studies that have reported disparity between limb and speech improvements after neurosurgical intervention for Parkinson's disease.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B26I</s0>
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<fC03 i1="01" i2="X" l="FRE"><s0>Parkinson maladie</s0>
<s5>01</s5>
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<s5>04</s5>
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<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Noyau sousthalamique</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Subthalamic nucleus</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Núcleo subtalámico</s0>
<s5>05</s5>
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<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Bilateral</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Bilateral</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Parole</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Speech</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Habla</s0>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Analyse parole</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Speech analysis</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Análisis palabra</s0>
<s5>08</s5>
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<fC03 i1="07" i2="X" l="FRE"><s0>Mesure acoustique</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Acoustic measurement</s0>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Medida acústica</s0>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Voix parlée</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Speaking voice</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Voz hablada</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Traitement instrumental</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Instrumentation therapy</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Tratamiento instrumental</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Evaluation performance</s0>
<s5>18</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Performance evaluation</s0>
<s5>18</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Evaluación prestación</s0>
<s5>18</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Adulte</s0>
<s5>20</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Adult</s0>
<s5>20</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Adulto</s0>
<s5>20</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Stimulation instrumentale</s0>
<s5>45</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Instrumental stimulation</s0>
<s5>45</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Estimulación instrumental</s0>
<s5>45</s5>
</fC07>
<fN21><s1>008</s1>
</fN21>
</pA>
</standard>
</inist>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice

An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice

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