Movement Disorders (revue)

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Estrogen use among nursing home residents with a diagnosis of Parkinson's disease

Identifieur interne : 002B14 ( PascalFrancis/Corpus ); précédent : 002B13; suivant : 002B15

Estrogen use among nursing home residents with a diagnosis of Parkinson's disease

Auteurs : Hubert H. Fernandez ; Kate L. Lapane

Source :

RBID : Pascal:01-0016453

Descripteurs français

English descriptors

Abstract

BACKGROUND: The role of estrogen in motor, cognitive, and behavioral functions in Parkinson's disease (PD) remains unclear. OBJECTIVES/METHODS: To determine differences in functional, cognitive, and behavioral patterns between estrogen users and non-users, we performed an observational study on 10,145 elderly women with PD using the Systematic Assessment in Geriatric drug use via Epidemiology (SAGE) database. The SAGE database consists of the Minimum Data Set (MDS), data collected on a cross-section of over 400,000 nursing home (NH) residents in five US states. Using a cross-sectional study design, we evaluated the demographics, physical and cognitive function, and mortality rates of women with PD who received estrogen (n = 195) versus those who did not receive estrogen (n = 9950). RESULTS: Independent of age, estrogen users were less cognitively impaired and more independent in their activities of daily living. Surprisingly, more estrogen users were depressed and more likely to be on an antidepressant than non-users. One-year death rates were comparable between estrogen users and non-users. CONCLUSION: This study supports the growing number of recent data suggesting estrogen's potential beneficial effects on PD motor and cognitive functions.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 15
A06       @2 6
A08 01  1  ENG  @1 Estrogen use among nursing home residents with a diagnosis of Parkinson's disease
A11 01  1    @1 FERNANDEZ (Hubert H.)
A11 02  1    @1 LAPANE (Kate L.)
A14 01      @1 Department of Clinical Neurosciences and Center for Gerontology and Health Care Research, Brown University School of Medicine @2 Providence, Rhode Island @3 USA @Z 1 aut.
A14 02      @1 Division of Neurology, Memorial Hospital of Rhode Island @2 Rhode Island @3 USA @Z 1 aut.
A14 03      @1 Department of Community Health and Center for Gerontology and Health Care Research, Brown University School of Medicine @2 Providence, Rhode Island @3 USA @Z 2 aut.
A20       @1 1119-1124
A21       @1 2000
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000092814950090
A44       @0 0000 @1 © 2001 INIST-CNRS. All rights reserved.
A45       @0 96 ref.
A47 01  1    @0 01-0016453
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 BACKGROUND: The role of estrogen in motor, cognitive, and behavioral functions in Parkinson's disease (PD) remains unclear. OBJECTIVES/METHODS: To determine differences in functional, cognitive, and behavioral patterns between estrogen users and non-users, we performed an observational study on 10,145 elderly women with PD using the Systematic Assessment in Geriatric drug use via Epidemiology (SAGE) database. The SAGE database consists of the Minimum Data Set (MDS), data collected on a cross-section of over 400,000 nursing home (NH) residents in five US states. Using a cross-sectional study design, we evaluated the demographics, physical and cognitive function, and mortality rates of women with PD who received estrogen (n = 195) versus those who did not receive estrogen (n = 9950). RESULTS: Independent of age, estrogen users were less cognitively impaired and more independent in their activities of daily living. Surprisingly, more estrogen users were depressed and more likely to be on an antidepressant than non-users. One-year death rates were comparable between estrogen users and non-users. CONCLUSION: This study supports the growing number of recent data suggesting estrogen's potential beneficial effects on PD motor and cognitive functions.
C02 01  X    @0 002B02O
C03 01  X  FRE  @0 Parkinson maladie @5 01
C03 01  X  ENG  @0 Parkinson disease @5 01
C03 01  X  SPA  @0 Parkinson enfermedad @5 01
C03 02  X  FRE  @0 Oestrogène @5 04
C03 02  X  ENG  @0 Estrogen @5 04
C03 02  X  SPA  @0 Estrógeno @5 04
C03 03  X  FRE  @0 Utilisation @5 05
C03 03  X  ENG  @0 Use @5 05
C03 03  X  SPA  @0 Utilización @5 05
C03 04  X  FRE  @0 Etablissement troisième âge @5 07
C03 04  X  ENG  @0 Homes for the aged @5 07
C03 04  X  SPA  @0 Establecimiento tercera edad @5 07
C03 05  X  FRE  @0 Démence @5 10
C03 05  X  ENG  @0 Dementia @5 10
C03 05  X  SPA  @0 Demencia @5 10
C03 06  X  FRE  @0 Capacité fonctionnelle @5 13
C03 06  X  ENG  @0 Functional capacity @5 13
C03 06  X  SPA  @0 Capacidad funcional @5 13
C03 07  X  FRE  @0 Mortalité @5 14
C03 07  X  ENG  @0 Mortality @5 14
C03 07  X  SPA  @0 Mortalidad @5 14
C03 08  X  FRE  @0 Etat dépressif @5 15
C03 08  X  ENG  @0 Depression @5 15
C03 08  X  SPA  @0 Estado depresivo @5 15
C03 09  X  FRE  @0 Etude comparative @5 17
C03 09  X  ENG  @0 Comparative study @5 17
C03 09  X  SPA  @0 Estudio comparativo @5 17
C03 10  X  FRE  @0 Traitement substitutif @5 18
C03 10  X  ENG  @0 Replacement therapy @5 18
C03 10  X  SPA  @0 Tratamiento sustitutivo @5 18
C03 11  X  FRE  @0 Epidémiologie @5 19
C03 11  X  ENG  @0 Epidemiology @5 19
C03 11  X  SPA  @0 Epidemiología @5 19
C03 12  X  FRE  @0 Personne âgée @5 20
C03 12  X  ENG  @0 Elderly @5 20
C03 12  X  SPA  @0 Anciano @5 20
C03 13  X  FRE  @0 Hormonothérapie @4 CD @5 96
C03 13  X  ENG  @0 Hormon replacement therapy @4 CD @5 96
C07 01  X  FRE  @0 Homme
C07 01  X  ENG  @0 Human
C07 01  X  SPA  @0 Hombre
C07 02  X  FRE  @0 Système nerveux pathologie @5 37
C07 02  X  ENG  @0 Nervous system diseases @5 37
C07 02  X  SPA  @0 Sistema nervioso patología @5 37
C07 03  X  FRE  @0 Système nerveux central pathologie @5 38
C07 03  X  ENG  @0 Central nervous system disease @5 38
C07 03  X  SPA  @0 Sistema nervosio central patología @5 38
C07 04  X  FRE  @0 Encéphale pathologie @5 39
C07 04  X  ENG  @0 Cerebral disorder @5 39
C07 04  X  SPA  @0 Encéfalo patología @5 39
C07 05  X  FRE  @0 Extrapyramidal syndrome @5 40
C07 05  X  ENG  @0 Extrapyramidal syndrome @5 40
C07 05  X  SPA  @0 Extrapiramidal síndrome @5 40
C07 06  X  FRE  @0 Maladie dégénérative @5 41
C07 06  X  ENG  @0 Degenerative disease @5 41
C07 06  X  SPA  @0 Enfermedad degenerativa @5 41
C07 07  X  FRE  @0 Trouble neurologique @5 61
C07 07  X  ENG  @0 Neurological disorder @5 61
C07 07  X  SPA  @0 Trastorno neurológico @5 61
C07 08  X  FRE  @0 Trouble cognition @5 62
C07 08  X  ENG  @0 Cognitive disorder @5 62
C07 08  X  SPA  @0 Trastorno cognitivo @5 62
C07 09  X  FRE  @0 Trouble humeur @5 69
C07 09  X  ENG  @0 Mood disorder @5 69
C07 09  X  SPA  @0 Trastorno humor @5 69
N21       @1 008

Format Inist (serveur)

NO : PASCAL 01-0016453 INIST
ET : Estrogen use among nursing home residents with a diagnosis of Parkinson's disease
AU : FERNANDEZ (Hubert H.); LAPANE (Kate L.)
AF : Department of Clinical Neurosciences and Center for Gerontology and Health Care Research, Brown University School of Medicine/Providence, Rhode Island/Etats-Unis (1 aut.); Division of Neurology, Memorial Hospital of Rhode Island/Rhode Island/Etats-Unis (1 aut.); Department of Community Health and Center for Gerontology and Health Care Research, Brown University School of Medicine/Providence, Rhode Island/Etats-Unis (2 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2000; Vol. 15; No. 6; Pp. 1119-1124; Bibl. 96 ref.
LA : Anglais
EA : BACKGROUND: The role of estrogen in motor, cognitive, and behavioral functions in Parkinson's disease (PD) remains unclear. OBJECTIVES/METHODS: To determine differences in functional, cognitive, and behavioral patterns between estrogen users and non-users, we performed an observational study on 10,145 elderly women with PD using the Systematic Assessment in Geriatric drug use via Epidemiology (SAGE) database. The SAGE database consists of the Minimum Data Set (MDS), data collected on a cross-section of over 400,000 nursing home (NH) residents in five US states. Using a cross-sectional study design, we evaluated the demographics, physical and cognitive function, and mortality rates of women with PD who received estrogen (n = 195) versus those who did not receive estrogen (n = 9950). RESULTS: Independent of age, estrogen users were less cognitively impaired and more independent in their activities of daily living. Surprisingly, more estrogen users were depressed and more likely to be on an antidepressant than non-users. One-year death rates were comparable between estrogen users and non-users. CONCLUSION: This study supports the growing number of recent data suggesting estrogen's potential beneficial effects on PD motor and cognitive functions.
CC : 002B02O
FD : Parkinson maladie; Oestrogène; Utilisation; Etablissement troisième âge; Démence; Capacité fonctionnelle; Mortalité; Etat dépressif; Etude comparative; Traitement substitutif; Epidémiologie; Personne âgée; Hormonothérapie
FG : Homme; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Trouble neurologique; Trouble cognition; Trouble humeur
ED : Parkinson disease; Estrogen; Use; Homes for the aged; Dementia; Functional capacity; Mortality; Depression; Comparative study; Replacement therapy; Epidemiology; Elderly; Hormon replacement therapy
EG : Human; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Neurological disorder; Cognitive disorder; Mood disorder
SD : Parkinson enfermedad; Estrógeno; Utilización; Establecimiento tercera edad; Demencia; Capacidad funcional; Mortalidad; Estado depresivo; Estudio comparativo; Tratamiento sustitutivo; Epidemiología; Anciano
LO : INIST-20953.354000092814950090
ID : 01-0016453

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Pascal:01-0016453

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<NO>PASCAL 01-0016453 INIST</NO>
<ET>Estrogen use among nursing home residents with a diagnosis of Parkinson's disease</ET>
<AU>FERNANDEZ (Hubert H.); LAPANE (Kate L.)</AU>
<AF>Department of Clinical Neurosciences and Center for Gerontology and Health Care Research, Brown University School of Medicine/Providence, Rhode Island/Etats-Unis (1 aut.); Division of Neurology, Memorial Hospital of Rhode Island/Rhode Island/Etats-Unis (1 aut.); Department of Community Health and Center for Gerontology and Health Care Research, Brown University School of Medicine/Providence, Rhode Island/Etats-Unis (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2000; Vol. 15; No. 6; Pp. 1119-1124; Bibl. 96 ref.</SO>
<LA>Anglais</LA>
<EA>BACKGROUND: The role of estrogen in motor, cognitive, and behavioral functions in Parkinson's disease (PD) remains unclear. OBJECTIVES/METHODS: To determine differences in functional, cognitive, and behavioral patterns between estrogen users and non-users, we performed an observational study on 10,145 elderly women with PD using the Systematic Assessment in Geriatric drug use via Epidemiology (SAGE) database. The SAGE database consists of the Minimum Data Set (MDS), data collected on a cross-section of over 400,000 nursing home (NH) residents in five US states. Using a cross-sectional study design, we evaluated the demographics, physical and cognitive function, and mortality rates of women with PD who received estrogen (n = 195) versus those who did not receive estrogen (n = 9950). RESULTS: Independent of age, estrogen users were less cognitively impaired and more independent in their activities of daily living. Surprisingly, more estrogen users were depressed and more likely to be on an antidepressant than non-users. One-year death rates were comparable between estrogen users and non-users. CONCLUSION: This study supports the growing number of recent data suggesting estrogen's potential beneficial effects on PD motor and cognitive functions.</EA>
<CC>002B02O</CC>
<FD>Parkinson maladie; Oestrogène; Utilisation; Etablissement troisième âge; Démence; Capacité fonctionnelle; Mortalité; Etat dépressif; Etude comparative; Traitement substitutif; Epidémiologie; Personne âgée; Hormonothérapie</FD>
<FG>Homme; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Trouble neurologique; Trouble cognition; Trouble humeur</FG>
<ED>Parkinson disease; Estrogen; Use; Homes for the aged; Dementia; Functional capacity; Mortality; Depression; Comparative study; Replacement therapy; Epidemiology; Elderly; Hormon replacement therapy</ED>
<EG>Human; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Neurological disorder; Cognitive disorder; Mood disorder</EG>
<SD>Parkinson enfermedad; Estrógeno; Utilización; Establecimiento tercera edad; Demencia; Capacidad funcional; Mortalidad; Estado depresivo; Estudio comparativo; Tratamiento sustitutivo; Epidemiología; Anciano</SD>
<LO>INIST-20953.354000092814950090</LO>
<ID>01-0016453</ID>
</server>
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