MovDisordV3, PascalFrancis, Corpus, bibRecord, 002A27

To test or not? The value of diagnostic tests in cervical dystonia

Identifieur interne : 002A27 ( PascalFrancis/Corpus ); précédent : 002A26; suivant : 002A28

To test or not? The value of diagnostic tests in cervical dystonia

Auteurs : Hilde Risvoll ; Emilia Kerty

Source :

Movement disorders [ 0885-3185 ] ; 2001.

RBID : Pascal:01-0332954

Descripteurs français

Pascal (Inist)
- Dystonie, Cou, Tomodensitométrie, Imagerie RMN, Radiographie, Rachis cervical, Liquide céphalorachidien, Exploration cytologique, Ferroxidase, Diagnostic, Marqueur biologique, Homme.

English descriptors

KwdEn :
- Biological marker, Cerebrospinal fluid, Cervical spine, Computerized axial tomography, Cytologic investigation, Diagnosis, Dystonia, Ferroxidase, Human, Neck, Nuclear magnetic resonance imaging, Radiography.

Abstract

It has long been suspected that idiopathic cervical dystonia is result of a dysfunction of the brain, but the cause of the disease has been elusive. The purpose of this study was to determine the diagnostical value of different radiological and laboratory tests in cases of cervical dystonia. Cerebral computer tomography and/or cerebral magnetic imaging were carried out in all of the 149 patients who were included in this study. A total of 25 scans revealed some minor findings that did not alter patients' management. Of the 128 cervical plain x-ray examinations, 63.1 % showed degenerative changes. Cerebrospinal fluid (CSF) was examined in 125 patients, and was normal in 103. Some degree of pathology was found in the remaining 22 CSF samples. All patients under the age of 50 years were tested for serum ceruloplasmin and no decreased level was found. Seven patients had elevated ANA titre; four of them also developed Botulinum toxin antibodies. We can conclude that the detection rate of pathologic findings in patients with idiopathic cervical dystonia is similar to what we can expect in the general population, provided the neurological findings are normal apart from the involuntary movements. In the adult form of typical cervical dystonia we do not recommend any standard laboratory or imaging tests if the neurological examination is normal aside from the abnormal head movements.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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C01	`01`		`ENG`	@0 It has long been suspected that idiopathic cervical dystonia is result of a dysfunction of the brain, but the cause of the disease has been elusive. The purpose of this study was to determine the diagnostical value of different radiological and laboratory tests in cases of cervical dystonia. Cerebral computer tomography and/or cerebral magnetic imaging were carried out in all of the 149 patients who were included in this study. A total of 25 scans revealed some minor findings that did not alter patients' management. Of the 128 cervical plain x-ray examinations, 63.1 % showed degenerative changes. Cerebrospinal fluid (CSF) was examined in 125 patients, and was normal in 103. Some degree of pathology was found in the remaining 22 CSF samples. All patients under the age of 50 years were tested for serum ceruloplasmin and no decreased level was found. Seven patients had elevated ANA titre; four of them also developed Botulinum toxin antibodies. We can conclude that the detection rate of pathologic findings in patients with idiopathic cervical dystonia is similar to what we can expect in the general population, provided the neurological findings are normal apart from the involuntary movements. In the adult form of typical cervical dystonia we do not recommend any standard laboratory or imaging tests if the neurological examination is normal aside from the abnormal head movements.
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Format Inist (serveur)

NO :	PASCAL 01-0332954 INIST
ET :	To test or not? The value of diagnostic tests in cervical dystonia
AU :	RISVOLL (Hilde); KERTY (Emilia)
AF :	Department of Neurology, The National Hospital, University of Oslo/Norvège (1 aut., 2 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2001; Vol. 16; No. 2; Pp. 286-289; Bibl. 20 ref.
LA :	Anglais
EA :	It has long been suspected that idiopathic cervical dystonia is result of a dysfunction of the brain, but the cause of the disease has been elusive. The purpose of this study was to determine the diagnostical value of different radiological and laboratory tests in cases of cervical dystonia. Cerebral computer tomography and/or cerebral magnetic imaging were carried out in all of the 149 patients who were included in this study. A total of 25 scans revealed some minor findings that did not alter patients' management. Of the 128 cervical plain x-ray examinations, 63.1 % showed degenerative changes. Cerebrospinal fluid (CSF) was examined in 125 patients, and was normal in 103. Some degree of pathology was found in the remaining 22 CSF samples. All patients under the age of 50 years were tested for serum ceruloplasmin and no decreased level was found. Seven patients had elevated ANA titre; four of them also developed Botulinum toxin antibodies. We can conclude that the detection rate of pathologic findings in patients with idiopathic cervical dystonia is similar to what we can expect in the general population, provided the neurological findings are normal apart from the involuntary movements. In the adult form of typical cervical dystonia we do not recommend any standard laboratory or imaging tests if the neurological examination is normal aside from the abnormal head movements.
CC :	002B17H
FD :	Dystonie; Cou; Tomodensitométrie; Imagerie RMN; Radiographie; Rachis cervical; Liquide céphalorachidien; Exploration cytologique; Ferroxidase; Diagnostic; Marqueur biologique; Homme
FG :	Oxidoreductases; Enzyme; Muscle strié pathologie; Système nerveux pathologie; Trouble neurologique; Mouvement involontaire; Extrapyramidal syndrome; Radiodiagnostic; Imagerie médicale; Système ostéoarticulaire
ED :	Dystonia; Neck; Computerized axial tomography; Nuclear magnetic resonance imaging; Radiography; Cervical spine; Cerebrospinal fluid; Cytologic investigation; Ferroxidase; Diagnosis; Biological marker; Human
EG :	Oxidoreductases; Enzyme; Striated muscle disease; Nervous system diseases; Neurological disorder; Involuntary movement; Extrapyramidal syndrome; Radiodiagnosis; Medical imagery; Osteoarticular system
SD :	Distonía; Cuello; Tomodensitometría; Imageria RMN; Radiografía; Raquis cervical; Líquido cefalorraquídeo; Estudio citológico; Ferroxidase; Diagnóstico; Marcador biológico; Hombre
LO :	INIST-20953.354000096545190160
ID :	01-0332954

Links to Exploration step

Pascal:01-0332954

Le document en format XML

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<front><div type="abstract" xml:lang="en">It has long been suspected that idiopathic cervical dystonia is result of a dysfunction of the brain, but the cause of the disease has been elusive. The purpose of this study was to determine the diagnostical value of different radiological and laboratory tests in cases of cervical dystonia. Cerebral computer tomography and/or cerebral magnetic imaging were carried out in all of the 149 patients who were included in this study. A total of 25 scans revealed some minor findings that did not alter patients' management. Of the 128 cervical plain x-ray examinations, 63.1 % showed degenerative changes. Cerebrospinal fluid (CSF) was examined in 125 patients, and was normal in 103. Some degree of pathology was found in the remaining 22 CSF samples. All patients under the age of 50 years were tested for serum ceruloplasmin and no decreased level was found. Seven patients had elevated ANA titre; four of them also developed Botulinum toxin antibodies. We can conclude that the detection rate of pathologic findings in patients with idiopathic cervical dystonia is similar to what we can expect in the general population, provided the neurological findings are normal apart from the involuntary movements. In the adult form of typical cervical dystonia we do not recommend any standard laboratory or imaging tests if the neurological examination is normal aside from the abnormal head movements.</div>
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<fC01 i1="01" l="ENG"><s0>It has long been suspected that idiopathic cervical dystonia is result of a dysfunction of the brain, but the cause of the disease has been elusive. The purpose of this study was to determine the diagnostical value of different radiological and laboratory tests in cases of cervical dystonia. Cerebral computer tomography and/or cerebral magnetic imaging were carried out in all of the 149 patients who were included in this study. A total of 25 scans revealed some minor findings that did not alter patients' management. Of the 128 cervical plain x-ray examinations, 63.1 % showed degenerative changes. Cerebrospinal fluid (CSF) was examined in 125 patients, and was normal in 103. Some degree of pathology was found in the remaining 22 CSF samples. All patients under the age of 50 years were tested for serum ceruloplasmin and no decreased level was found. Seven patients had elevated ANA titre; four of them also developed Botulinum toxin antibodies. We can conclude that the detection rate of pathologic findings in patients with idiopathic cervical dystonia is similar to what we can expect in the general population, provided the neurological findings are normal apart from the involuntary movements. In the adult form of typical cervical dystonia we do not recommend any standard laboratory or imaging tests if the neurological examination is normal aside from the abnormal head movements.</s0>
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<s5>18</s5>
</fC03>
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<s5>20</s5>
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<s5>20</s5>
</fC03>
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<s5>20</s5>
</fC03>
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<s2>FE</s2>
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<s2>FE</s2>
</fC07>
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<s2>FE</s2>
</fC07>
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<s5>37</s5>
</fC07>
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<s5>37</s5>
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<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>38</s5>
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<s5>39</s5>
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<s5>39</s5>
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<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Mouvement involontaire</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Involuntary movement</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Movimiento involuntario</s0>
<s5>40</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Radiodiagnostic</s0>
<s5>45</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Radiodiagnosis</s0>
<s5>45</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Radiodiagnóstico</s0>
<s5>45</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Imagerie médicale</s0>
<s5>46</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Medical imagery</s0>
<s5>46</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Imageneria medical</s0>
<s5>46</s5>
</fC07>
<fC07 i1="10" i2="X" l="FRE"><s0>Système ostéoarticulaire</s0>
<s5>53</s5>
</fC07>
<fC07 i1="10" i2="X" l="ENG"><s0>Osteoarticular system</s0>
<s5>53</s5>
</fC07>
<fC07 i1="10" i2="X" l="SPA"><s0>Sistema osteoarticular</s0>
<s5>53</s5>
</fC07>
<fN21><s1>232</s1>
</fN21>
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<server><NO>PASCAL 01-0332954 INIST</NO>
<ET>To test or not? The value of diagnostic tests in cervical dystonia</ET>
<AU>RISVOLL (Hilde); KERTY (Emilia)</AU>
<AF>Department of Neurology, The National Hospital, University of Oslo/Norvège (1 aut., 2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2001; Vol. 16; No. 2; Pp. 286-289; Bibl. 20 ref.</SO>
<LA>Anglais</LA>
<EA>It has long been suspected that idiopathic cervical dystonia is result of a dysfunction of the brain, but the cause of the disease has been elusive. The purpose of this study was to determine the diagnostical value of different radiological and laboratory tests in cases of cervical dystonia. Cerebral computer tomography and/or cerebral magnetic imaging were carried out in all of the 149 patients who were included in this study. A total of 25 scans revealed some minor findings that did not alter patients' management. Of the 128 cervical plain x-ray examinations, 63.1 % showed degenerative changes. Cerebrospinal fluid (CSF) was examined in 125 patients, and was normal in 103. Some degree of pathology was found in the remaining 22 CSF samples. All patients under the age of 50 years were tested for serum ceruloplasmin and no decreased level was found. Seven patients had elevated ANA titre; four of them also developed Botulinum toxin antibodies. We can conclude that the detection rate of pathologic findings in patients with idiopathic cervical dystonia is similar to what we can expect in the general population, provided the neurological findings are normal apart from the involuntary movements. In the adult form of typical cervical dystonia we do not recommend any standard laboratory or imaging tests if the neurological examination is normal aside from the abnormal head movements.</EA>
<CC>002B17H</CC>
<FD>Dystonie; Cou; Tomodensitométrie; Imagerie RMN; Radiographie; Rachis cervical; Liquide céphalorachidien; Exploration cytologique; Ferroxidase; Diagnostic; Marqueur biologique; Homme</FD>
<FG>Oxidoreductases; Enzyme; Muscle strié pathologie; Système nerveux pathologie; Trouble neurologique; Mouvement involontaire; Extrapyramidal syndrome; Radiodiagnostic; Imagerie médicale; Système ostéoarticulaire</FG>
<ED>Dystonia; Neck; Computerized axial tomography; Nuclear magnetic resonance imaging; Radiography; Cervical spine; Cerebrospinal fluid; Cytologic investigation; Ferroxidase; Diagnosis; Biological marker; Human</ED>
<EG>Oxidoreductases; Enzyme; Striated muscle disease; Nervous system diseases; Neurological disorder; Involuntary movement; Extrapyramidal syndrome; Radiodiagnosis; Medical imagery; Osteoarticular system</EG>
<SD>Distonía; Cuello; Tomodensitometría; Imageria RMN; Radiografía; Raquis cervical; Líquido cefalorraquídeo; Estudio citológico; Ferroxidase; Diagnóstico; Marcador biológico; Hombre</SD>
<LO>INIST-20953.354000096545190160</LO>
<ID>01-0332954</ID>
</server>
</inist>
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	Movement Disorders (revue)
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Movement Disorders (revue)

To test or not? The value of diagnostic tests in cervical dystonia

To test or not? The value of diagnostic tests in cervical dystonia

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