MovDisordV3, PascalFrancis, Corpus, bibRecord, 002885

Spontaneously changing muscular activation pattern in patients with cervical dystonia

Identifieur interne : 002885 ( PascalFrancis/Corpus ); précédent : 002884; suivant : 002886

Spontaneously changing muscular activation pattern in patients with cervical dystonia

Auteurs : A. Münchau ; S. R. Filipovic ; A. Oester-Barkey ; N. P. Quinn ; J. C. Rothwell ; K. P. Bhatia

Source :

Movement disorders [ 0885-3185 ] ; 2001.

RBID : Pascal:02-0177067

Descripteurs français

Pascal (Inist)
- Torticolis spasmodique, Electromyographie, Enregistrement vidéo, Activation, Muscle strié, Spontané, Physiopathologie, Homme.

English descriptors

KwdEn :
- Activation, Electromyography, Human, Pathophysiology, Spasmodic torticollis, Spontaneous, Striated muscle, Video recording.

Abstract

The objective of this study was to determine stability of the neck muscle activation pattern in a given dystonic head position in patients with cervical dystonia (CD). We assessed 26 patients with CD and botulinum toxin (BT) treatment failure before surgical denervation, None of them had received BT injections for at least 4 months. To relate dystonic head position to underlying neck muscle activity, we used synchronised video and poly-electromyographic (EMG) recording over a period of 10 minutes. The muscle activation pattern during constant ("stable") maximal dystonic excursions was analysed. EMG data of nine patients was excluded from the analysis, as these patients had a constantly changing head position or marked head tremor. In the remaining 17 patients, who had a fairly stable dystonic position, muscular activation patterns during the recording spontaneously changed in nine (Group A) while in eight it remained stable (Group B). There was no significant difference in demographic variables between the two groups other than a male predominance in Group A. However, the retrospectively determined initial response to BT treatment (before BT treatment failure had occurred) was significantly worse in Group A as compared with Group B. Neck muscle activation patterns can spontaneously change in CD patients despite constant dystonic head position, implying an inherent variability of the underlying central motor program in some patients. This should be considered when BT treatment response is unsatisfactory, and should also be taken into account when interpreting results of EMG recordings of neck muscles in these patients.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03		`1`		`@0 Mov. disord.`
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A08	`01`	`1`	`ENG`	`@1 Spontaneously changing muscular activation pattern in patients with cervical dystonia`
A11	`01`	`1`		`@1 MÜNCHAU (A.)`
A11	`02`	`1`		`@1 FILIPOVIC (S. R.)`
A11	`03`	`1`		`@1 OESTER-BARKEY (A.)`
A11	`04`	`1`		`@1 QUINN (N. P.)`
A11	`05`	`1`		`@1 ROTHWELL (J. C.)`
A11	`06`	`1`		`@1 BHATIA (K. P.)`
A14	`01`			`@1 MRC Human Movement and Balance Unit, Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery @2 London @3 GBR @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 5 aut.`
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A23	`01`			`@0 ENG`
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A44				`@0 0000 @1 © 2002 INIST-CNRS. All rights reserved.`
A45				`@0 20 ref.`
A47	`01`	`1`		`@0 02-0177067`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
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C01	`01`		`ENG`	@0 The objective of this study was to determine stability of the neck muscle activation pattern in a given dystonic head position in patients with cervical dystonia (CD). We assessed 26 patients with CD and botulinum toxin (BT) treatment failure before surgical denervation, None of them had received BT injections for at least 4 months. To relate dystonic head position to underlying neck muscle activity, we used synchronised video and poly-electromyographic (EMG) recording over a period of 10 minutes. The muscle activation pattern during constant ("stable") maximal dystonic excursions was analysed. EMG data of nine patients was excluded from the analysis, as these patients had a constantly changing head position or marked head tremor. In the remaining 17 patients, who had a fairly stable dystonic position, muscular activation patterns during the recording spontaneously changed in nine (Group A) while in eight it remained stable (Group B). There was no significant difference in demographic variables between the two groups other than a male predominance in Group A. However, the retrospectively determined initial response to BT treatment (before BT treatment failure had occurred) was significantly worse in Group A as compared with Group B. Neck muscle activation patterns can spontaneously change in CD patients despite constant dystonic head position, implying an inherent variability of the underlying central motor program in some patients. This should be considered when BT treatment response is unsatisfactory, and should also be taken into account when interpreting results of EMG recordings of neck muscles in these patients.
C02	`01`	`X`		`@0 002B17A01`
C03	`01`	`X`	`FRE`	`@0 Torticolis spasmodique @5 01`
C03	`01`	`X`	`ENG`	`@0 Spasmodic torticollis @5 01`
C03	`01`	`X`	`SPA`	`@0 Tortícolis espasmódico @5 01`
C03	`02`	`X`	`FRE`	`@0 Electromyographie @5 04`
C03	`02`	`X`	`ENG`	`@0 Electromyography @5 04`
C03	`02`	`X`	`SPA`	`@0 Electromiografía @5 04`
C03	`03`	`X`	`FRE`	`@0 Enregistrement vidéo @5 05`
C03	`03`	`X`	`ENG`	`@0 Video recording @5 05`
C03	`03`	`X`	`SPA`	`@0 Registro vídeo @5 05`
C03	`04`	`X`	`FRE`	`@0 Activation @5 07`
C03	`04`	`X`	`ENG`	`@0 Activation @5 07`
C03	`04`	`X`	`SPA`	`@0 Activación @5 07`
C03	`05`	`X`	`FRE`	`@0 Muscle strié @5 08`
C03	`05`	`X`	`ENG`	`@0 Striated muscle @5 08`
C03	`05`	`X`	`SPA`	`@0 Músculo estriado @5 08`
C03	`06`	`X`	`FRE`	`@0 Spontané @5 16`
C03	`06`	`X`	`ENG`	`@0 Spontaneous @5 16`
C03	`06`	`X`	`SPA`	`@0 Espontáneo @5 16`
C03	`07`	`X`	`FRE`	`@0 Physiopathologie @5 17`
C03	`07`	`X`	`ENG`	`@0 Pathophysiology @5 17`
C03	`07`	`X`	`SPA`	`@0 Fisiopatología @5 17`
C03	`08`	`X`	`FRE`	`@0 Homme @5 20`
C03	`08`	`X`	`ENG`	`@0 Human @5 20`
C03	`08`	`X`	`SPA`	`@0 Hombre @5 20`
C07	`01`	`X`	`FRE`	`@0 Muscle strié pathologie @5 37`
C07	`01`	`X`	`ENG`	`@0 Striated muscle disease @5 37`
C07	`01`	`X`	`SPA`	`@0 Músculo estriado patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Système nerveux pathologie @5 38`
C07	`02`	`X`	`ENG`	`@0 Nervous system diseases @5 38`
C07	`02`	`X`	`SPA`	`@0 Sistema nervioso patología @5 38`
C07	`03`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 39`
C07	`03`	`X`	`ENG`	`@0 Central nervous system disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 39`
C07	`04`	`X`	`FRE`	`@0 Encéphale pathologie @5 40`
C07	`04`	`X`	`ENG`	`@0 Cerebral disorder @5 40`
C07	`04`	`X`	`SPA`	`@0 Encéfalo patología @5 40`
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C07	`05`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 41`
C07	`05`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 41`
C07	`06`	`X`	`FRE`	`@0 Electrodiagnostic @5 45`
C07	`06`	`X`	`ENG`	`@0 Electrodiagnosis @5 45`
C07	`06`	`X`	`SPA`	`@0 Electrodiagnóstico @5 45`
N21				`@1 098`
N82				`@1 PSI`

Format Inist (serveur)

NO :	PASCAL 02-0177067 INIST
ET :	Spontaneously changing muscular activation pattern in patients with cervical dystonia
AU :	MÜNCHAU (A.); FILIPOVIC (S. R.); OESTER-BARKEY (A.); QUINN (N. P.); ROTHWELL (J. C.); BHATIA (K. P.)
AF :	MRC Human Movement and Balance Unit, Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery/London/Royaume-Uni (1 aut., 2 aut., 3 aut., 5 aut.); University Department of Clinical Neurology, Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery/London/Royaume-Uni (4 aut., 6 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2001; Vol. 16; No. 6; Pp. 1091-1097; Bibl. 20 ref.
LA :	Anglais
EA :	The objective of this study was to determine stability of the neck muscle activation pattern in a given dystonic head position in patients with cervical dystonia (CD). We assessed 26 patients with CD and botulinum toxin (BT) treatment failure before surgical denervation, None of them had received BT injections for at least 4 months. To relate dystonic head position to underlying neck muscle activity, we used synchronised video and poly-electromyographic (EMG) recording over a period of 10 minutes. The muscle activation pattern during constant ("stable") maximal dystonic excursions was analysed. EMG data of nine patients was excluded from the analysis, as these patients had a constantly changing head position or marked head tremor. In the remaining 17 patients, who had a fairly stable dystonic position, muscular activation patterns during the recording spontaneously changed in nine (Group A) while in eight it remained stable (Group B). There was no significant difference in demographic variables between the two groups other than a male predominance in Group A. However, the retrospectively determined initial response to BT treatment (before BT treatment failure had occurred) was significantly worse in Group A as compared with Group B. Neck muscle activation patterns can spontaneously change in CD patients despite constant dystonic head position, implying an inherent variability of the underlying central motor program in some patients. This should be considered when BT treatment response is unsatisfactory, and should also be taken into account when interpreting results of EMG recordings of neck muscles in these patients.
CC :	002B17A01
FD :	Torticolis spasmodique; Electromyographie; Enregistrement vidéo; Activation; Muscle strié; Spontané; Physiopathologie; Homme
FG :	Muscle strié pathologie; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Electrodiagnostic
ED :	Spasmodic torticollis; Electromyography; Video recording; Activation; Striated muscle; Spontaneous; Pathophysiology; Human
EG :	Striated muscle disease; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Electrodiagnosis
SD :	Tortícolis espasmódico; Electromiografía; Registro vídeo; Activación; Músculo estriado; Espontáneo; Fisiopatología; Hombre
LO :	INIST-20953.354000094252170110
ID :	02-0177067

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Pascal:02-0177067

Le document en format XML

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<front><div type="abstract" xml:lang="en">The objective of this study was to determine stability of the neck muscle activation pattern in a given dystonic head position in patients with cervical dystonia (CD). We assessed 26 patients with CD and botulinum toxin (BT) treatment failure before surgical denervation, None of them had received BT injections for at least 4 months. To relate dystonic head position to underlying neck muscle activity, we used synchronised video and poly-electromyographic (EMG) recording over a period of 10 minutes. The muscle activation pattern during constant ("stable") maximal dystonic excursions was analysed. EMG data of nine patients was excluded from the analysis, as these patients had a constantly changing head position or marked head tremor. In the remaining 17 patients, who had a fairly stable dystonic position, muscular activation patterns during the recording spontaneously changed in nine (Group A) while in eight it remained stable (Group B). There was no significant difference in demographic variables between the two groups other than a male predominance in Group A. However, the retrospectively determined initial response to BT treatment (before BT treatment failure had occurred) was significantly worse in Group A as compared with Group B. Neck muscle activation patterns can spontaneously change in CD patients despite constant dystonic head position, implying an inherent variability of the underlying central motor program in some patients. This should be considered when BT treatment response is unsatisfactory, and should also be taken into account when interpreting results of EMG recordings of neck muscles in these patients.</div>
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<fC01 i1="01" l="ENG"><s0>The objective of this study was to determine stability of the neck muscle activation pattern in a given dystonic head position in patients with cervical dystonia (CD). We assessed 26 patients with CD and botulinum toxin (BT) treatment failure before surgical denervation, None of them had received BT injections for at least 4 months. To relate dystonic head position to underlying neck muscle activity, we used synchronised video and poly-electromyographic (EMG) recording over a period of 10 minutes. The muscle activation pattern during constant ("stable") maximal dystonic excursions was analysed. EMG data of nine patients was excluded from the analysis, as these patients had a constantly changing head position or marked head tremor. In the remaining 17 patients, who had a fairly stable dystonic position, muscular activation patterns during the recording spontaneously changed in nine (Group A) while in eight it remained stable (Group B). There was no significant difference in demographic variables between the two groups other than a male predominance in Group A. However, the retrospectively determined initial response to BT treatment (before BT treatment failure had occurred) was significantly worse in Group A as compared with Group B. Neck muscle activation patterns can spontaneously change in CD patients despite constant dystonic head position, implying an inherent variability of the underlying central motor program in some patients. This should be considered when BT treatment response is unsatisfactory, and should also be taken into account when interpreting results of EMG recordings of neck muscles in these patients.</s0>
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<fC03 i1="01" i2="X" l="FRE"><s0>Torticolis spasmodique</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Spasmodic torticollis</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Tortícolis espasmódico</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Electromyographie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Electromyography</s0>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Electromiografía</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Enregistrement vidéo</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Video recording</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Registro vídeo</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Activation</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Activation</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Activación</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Muscle strié</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Striated muscle</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Músculo estriado</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Spontané</s0>
<s5>16</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Spontaneous</s0>
<s5>16</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Espontáneo</s0>
<s5>16</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Physiopathologie</s0>
<s5>17</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Pathophysiology</s0>
<s5>17</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Fisiopatología</s0>
<s5>17</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Homme</s0>
<s5>20</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Human</s0>
<s5>20</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Hombre</s0>
<s5>20</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Muscle strié pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Striated muscle disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Músculo estriado patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Electrodiagnostic</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Electrodiagnosis</s0>
<s5>45</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Electrodiagnóstico</s0>
<s5>45</s5>
</fC07>
<fN21><s1>098</s1>
</fN21>
<fN82><s1>PSI</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 02-0177067 INIST</NO>
<ET>Spontaneously changing muscular activation pattern in patients with cervical dystonia</ET>
<AU>MÜNCHAU (A.); FILIPOVIC (S. R.); OESTER-BARKEY (A.); QUINN (N. P.); ROTHWELL (J. C.); BHATIA (K. P.)</AU>
<AF>MRC Human Movement and Balance Unit, Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery/London/Royaume-Uni (1 aut., 2 aut., 3 aut., 5 aut.); University Department of Clinical Neurology, Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery/London/Royaume-Uni (4 aut., 6 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2001; Vol. 16; No. 6; Pp. 1091-1097; Bibl. 20 ref.</SO>
<LA>Anglais</LA>
<EA>The objective of this study was to determine stability of the neck muscle activation pattern in a given dystonic head position in patients with cervical dystonia (CD). We assessed 26 patients with CD and botulinum toxin (BT) treatment failure before surgical denervation, None of them had received BT injections for at least 4 months. To relate dystonic head position to underlying neck muscle activity, we used synchronised video and poly-electromyographic (EMG) recording over a period of 10 minutes. The muscle activation pattern during constant ("stable") maximal dystonic excursions was analysed. EMG data of nine patients was excluded from the analysis, as these patients had a constantly changing head position or marked head tremor. In the remaining 17 patients, who had a fairly stable dystonic position, muscular activation patterns during the recording spontaneously changed in nine (Group A) while in eight it remained stable (Group B). There was no significant difference in demographic variables between the two groups other than a male predominance in Group A. However, the retrospectively determined initial response to BT treatment (before BT treatment failure had occurred) was significantly worse in Group A as compared with Group B. Neck muscle activation patterns can spontaneously change in CD patients despite constant dystonic head position, implying an inherent variability of the underlying central motor program in some patients. This should be considered when BT treatment response is unsatisfactory, and should also be taken into account when interpreting results of EMG recordings of neck muscles in these patients.</EA>
<CC>002B17A01</CC>
<FD>Torticolis spasmodique; Electromyographie; Enregistrement vidéo; Activation; Muscle strié; Spontané; Physiopathologie; Homme</FD>
<FG>Muscle strié pathologie; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Electrodiagnostic</FG>
<ED>Spasmodic torticollis; Electromyography; Video recording; Activation; Striated muscle; Spontaneous; Pathophysiology; Human</ED>
<EG>Striated muscle disease; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Electrodiagnosis</EG>
<SD>Tortícolis espasmódico; Electromiografía; Registro vídeo; Activación; Músculo estriado; Espontáneo; Fisiopatología; Hombre</SD>
<LO>INIST-20953.354000094252170110</LO>
<ID>02-0177067</ID>
</server>
</inist>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Spontaneously changing muscular activation pattern in patients with cervical dystonia

Spontaneously changing muscular activation pattern in patients with cervical dystonia

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