Movement Disorders (revue)

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Secondary paroxysmal dyskinesias

Identifieur interne : 002699 ( PascalFrancis/Corpus ); précédent : 002698; suivant : 002700

Secondary paroxysmal dyskinesias

Auteurs : Jaishri Blakeley ; Joseph Jankovic

Source :

RBID : Pascal:02-0456858

Descripteurs français

English descriptors

Abstract

Paroxysmal dyskinesias (PxDs) are involuntary, episodic movements that include paroxysmal kinesigenic (PKD), paroxysmal nonkinesigenic (PNKD), and paroxysmal hypnogenic (PHD) varieties. Although most PxDs are primary (idiopathic or genetic), we found 17 of our 76 patients with PxD (22%) to have an identifiable cause for their PxD (10 men; mean age, 41.4 years). Causes included peripheral trauma (in three patients), vascular lesions (in four), central trauma (in four), kernicterus (in two), multiple sclerosis (in one), cytomegalovirus encephalitis (in one), meningovascular syphilis (in one), and migraine (in one). The latency from insult to symptom onset ranged from days (trauma) to 18 years (kernicterus), with a mean of 3 years. Nine patients had PNKD, two had PKD, five had mixed PKD/PNKD, and one had PHD. Hemidystonia was the most common expression of the paroxysmal movement disorder, present in 11 patients. Both of the patients with PKD had symptom durations of <5 minutes. Symptom duration ranged from 10 seconds to 15 days for PNKD and from 5 minutes to 45 minutes for mixed PKD/PNKD. There were no uniformly effective therapies, but anticonvulsant drugs, clonazepam, and botulinum toxin injections were the most beneficial. Awareness of the variable phenomenology and the spectrum of causes associated with secondary PxD will allow for more timely diagnosis and early intervention.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
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A03   1    @0 Mov. disord.
A05       @2 17
A06       @2 4
A08 01  1  ENG  @1 Secondary paroxysmal dyskinesias
A11 01  1    @1 BLAKELEY (Jaishri)
A11 02  1    @1 JANKOVIC (Joseph)
A14 01      @1 Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine @2 Houston, Texas @3 USA @Z 1 aut. @Z 2 aut.
A20       @1 726-734
A21       @1 2002
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000108922560130
A44       @0 0000 @1 © 2002 INIST-CNRS. All rights reserved.
A45       @0 56 ref.
A47 01  1    @0 02-0456858
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
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C01 01    ENG  @0 Paroxysmal dyskinesias (PxDs) are involuntary, episodic movements that include paroxysmal kinesigenic (PKD), paroxysmal nonkinesigenic (PNKD), and paroxysmal hypnogenic (PHD) varieties. Although most PxDs are primary (idiopathic or genetic), we found 17 of our 76 patients with PxD (22%) to have an identifiable cause for their PxD (10 men; mean age, 41.4 years). Causes included peripheral trauma (in three patients), vascular lesions (in four), central trauma (in four), kernicterus (in two), multiple sclerosis (in one), cytomegalovirus encephalitis (in one), meningovascular syphilis (in one), and migraine (in one). The latency from insult to symptom onset ranged from days (trauma) to 18 years (kernicterus), with a mean of 3 years. Nine patients had PNKD, two had PKD, five had mixed PKD/PNKD, and one had PHD. Hemidystonia was the most common expression of the paroxysmal movement disorder, present in 11 patients. Both of the patients with PKD had symptom durations of <5 minutes. Symptom duration ranged from 10 seconds to 15 days for PNKD and from 5 minutes to 45 minutes for mixed PKD/PNKD. There were no uniformly effective therapies, but anticonvulsant drugs, clonazepam, and botulinum toxin injections were the most beneficial. Awareness of the variable phenomenology and the spectrum of causes associated with secondary PxD will allow for more timely diagnosis and early intervention.
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C03 01  X  ENG  @0 Dyskinesia @5 01
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C03 05  X  ENG  @0 Time lag @5 05
C03 05  X  SPA  @0 Plazo @5 05
C03 06  X  FRE  @0 Symptomatologie @5 07
C03 06  X  ENG  @0 Symptomatology @5 07
C03 06  X  SPA  @0 Sintomatología @5 07
C03 07  X  FRE  @0 Etiologie @5 17
C03 07  X  ENG  @0 Etiology @5 17
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C07 02  X  ENG  @0 Neurological disorder @5 38
C07 02  X  SPA  @0 Trastorno neurológico @5 38
C07 03  X  FRE  @0 Mouvement involontaire @5 39
C07 03  X  ENG  @0 Involuntary movement @5 39
C07 03  X  SPA  @0 Movimiento involuntario @5 39
C07 04  X  FRE  @0 Extrapyramidal syndrome @5 40
C07 04  X  ENG  @0 Extrapyramidal syndrome @5 40
C07 04  X  SPA  @0 Extrapiramidal síndrome @5 40
N21       @1 266
N82       @1 PSI

Format Inist (serveur)

NO : PASCAL 02-0456858 INIST
ET : Secondary paroxysmal dyskinesias
AU : BLAKELEY (Jaishri); JANKOVIC (Joseph)
AF : Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine/Houston, Texas/Etats-Unis (1 aut., 2 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2002; Vol. 17; No. 4; Pp. 726-734; Bibl. 56 ref.
LA : Anglais
EA : Paroxysmal dyskinesias (PxDs) are involuntary, episodic movements that include paroxysmal kinesigenic (PKD), paroxysmal nonkinesigenic (PNKD), and paroxysmal hypnogenic (PHD) varieties. Although most PxDs are primary (idiopathic or genetic), we found 17 of our 76 patients with PxD (22%) to have an identifiable cause for their PxD (10 men; mean age, 41.4 years). Causes included peripheral trauma (in three patients), vascular lesions (in four), central trauma (in four), kernicterus (in two), multiple sclerosis (in one), cytomegalovirus encephalitis (in one), meningovascular syphilis (in one), and migraine (in one). The latency from insult to symptom onset ranged from days (trauma) to 18 years (kernicterus), with a mean of 3 years. Nine patients had PNKD, two had PKD, five had mixed PKD/PNKD, and one had PHD. Hemidystonia was the most common expression of the paroxysmal movement disorder, present in 11 patients. Both of the patients with PKD had symptom durations of <5 minutes. Symptom duration ranged from 10 seconds to 15 days for PNKD and from 5 minutes to 45 minutes for mixed PKD/PNKD. There were no uniformly effective therapies, but anticonvulsant drugs, clonazepam, and botulinum toxin injections were the most beneficial. Awareness of the variable phenomenology and the spectrum of causes associated with secondary PxD will allow for more timely diagnosis and early intervention.
CC : 002B17A01
FD : Dyskinésie; Brutal; Secondaire; Age apparition; Délai; Symptomatologie; Etiologie; Revue bibliographique; Homme
FG : Système nerveux pathologie; Trouble neurologique; Mouvement involontaire; Extrapyramidal syndrome
ED : Dyskinesia; Sudden; Secondary; Age of onset; Time lag; Symptomatology; Etiology; Bibliographic review; Human
EG : Nervous system diseases; Neurological disorder; Involuntary movement; Extrapyramidal syndrome
SD : Disquinesia; Súbito; Secundario; Edad aparición; Plazo; Sintomatología; Etiología; Revista bibliográfica; Hombre
LO : INIST-20953.354000108922560130
ID : 02-0456858

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Pascal:02-0456858

Le document en format XML

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<div type="abstract" xml:lang="en">Paroxysmal dyskinesias (PxDs) are involuntary, episodic movements that include paroxysmal kinesigenic (PKD), paroxysmal nonkinesigenic (PNKD), and paroxysmal hypnogenic (PHD) varieties. Although most PxDs are primary (idiopathic or genetic), we found 17 of our 76 patients with PxD (22%) to have an identifiable cause for their PxD (10 men; mean age, 41.4 years). Causes included peripheral trauma (in three patients), vascular lesions (in four), central trauma (in four), kernicterus (in two), multiple sclerosis (in one), cytomegalovirus encephalitis (in one), meningovascular syphilis (in one), and migraine (in one). The latency from insult to symptom onset ranged from days (trauma) to 18 years (kernicterus), with a mean of 3 years. Nine patients had PNKD, two had PKD, five had mixed PKD/PNKD, and one had PHD. Hemidystonia was the most common expression of the paroxysmal movement disorder, present in 11 patients. Both of the patients with PKD had symptom durations of <5 minutes. Symptom duration ranged from 10 seconds to 15 days for PNKD and from 5 minutes to 45 minutes for mixed PKD/PNKD. There were no uniformly effective therapies, but anticonvulsant drugs, clonazepam, and botulinum toxin injections were the most beneficial. Awareness of the variable phenomenology and the spectrum of causes associated with secondary PxD will allow for more timely diagnosis and early intervention.</div>
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<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2002; Vol. 17; No. 4; Pp. 726-734; Bibl. 56 ref.</SO>
<LA>Anglais</LA>
<EA>Paroxysmal dyskinesias (PxDs) are involuntary, episodic movements that include paroxysmal kinesigenic (PKD), paroxysmal nonkinesigenic (PNKD), and paroxysmal hypnogenic (PHD) varieties. Although most PxDs are primary (idiopathic or genetic), we found 17 of our 76 patients with PxD (22%) to have an identifiable cause for their PxD (10 men; mean age, 41.4 years). Causes included peripheral trauma (in three patients), vascular lesions (in four), central trauma (in four), kernicterus (in two), multiple sclerosis (in one), cytomegalovirus encephalitis (in one), meningovascular syphilis (in one), and migraine (in one). The latency from insult to symptom onset ranged from days (trauma) to 18 years (kernicterus), with a mean of 3 years. Nine patients had PNKD, two had PKD, five had mixed PKD/PNKD, and one had PHD. Hemidystonia was the most common expression of the paroxysmal movement disorder, present in 11 patients. Both of the patients with PKD had symptom durations of <5 minutes. Symptom duration ranged from 10 seconds to 15 days for PNKD and from 5 minutes to 45 minutes for mixed PKD/PNKD. There were no uniformly effective therapies, but anticonvulsant drugs, clonazepam, and botulinum toxin injections were the most beneficial. Awareness of the variable phenomenology and the spectrum of causes associated with secondary PxD will allow for more timely diagnosis and early intervention.</EA>
<CC>002B17A01</CC>
<FD>Dyskinésie; Brutal; Secondaire; Age apparition; Délai; Symptomatologie; Etiologie; Revue bibliographique; Homme</FD>
<FG>Système nerveux pathologie; Trouble neurologique; Mouvement involontaire; Extrapyramidal syndrome</FG>
<ED>Dyskinesia; Sudden; Secondary; Age of onset; Time lag; Symptomatology; Etiology; Bibliographic review; Human</ED>
<EG>Nervous system diseases; Neurological disorder; Involuntary movement; Extrapyramidal syndrome</EG>
<SD>Disquinesia; Súbito; Secundario; Edad aparición; Plazo; Sintomatología; Etiología; Revista bibliográfica; Hombre</SD>
<LO>INIST-20953.354000108922560130</LO>
<ID>02-0456858</ID>
</server>
</inist>
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