Movement Disorders (revue)

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Prevalence of PD and other types of parkinsonism in three elderly populations of central Spain

Identifieur interne : 002519 ( PascalFrancis/Corpus ); précédent : 002518; suivant : 002520

Prevalence of PD and other types of parkinsonism in three elderly populations of central Spain

Auteurs : Julian Benito-Leon ; Félix Bermejo-Pareja ; Javier Rodriguez ; José-Antonio Molina ; Rafael Gabriel ; José-Manuel Morales

Source :

RBID : Pascal:03-0238136

Descripteurs français

English descriptors

Abstract

The prevalence of Parkinson's disease (PD) and other types of parkinsonism in three elderly populations of central Spain was investigated using a door-to-door, two-phase approach. This design called for the administration of a brief questionnaire to subjects 65 years of age or older taken from the census of one urban municipality of Greater Madrid (Margaritas, Getafe), one rural site (Arévalo County, Ávila), and one urban district of Madrid (Lista) in Spain (N = 5,278). Study neurologists extensively investigated those subjects who screened positively. The diagnoses, based on specified criteria, were reviewed to increase reliability across neurologists. We found 118 subjects with parkinsonism: 81 affected by PD (68.6%), 26 drug-induced parkinsonism (22.0%), 6 parkinsonism in dementia (5.1%), 3 vascular parkinsonism (2.5%), and 2 unspecified parkinsonism (1.7%). The prevalence was 2.2% (95% confidence interval [CI], 1.8 -2.6) for all types of parkinsonism and 1.5% (95% CI, 1.2-1.8) for PD. The prevalence estimates of parkinsonism and PD increased with age, declining at 85 years and over. Age prevalence ratios were higher for men. Twenty-three subjects (28.4%) of the subjects with PD were detected through the screening and had not been diagnosed previously. Overall prevalence estimates of PD and other types of parkinsonism in central Spain rank at levels similar to those recently reported for other European and non-European elderly populations. Despite improvement in access to health services, an important proportion of PD patients may never seek neurological attention.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A08 01  1  ENG  @1 Prevalence of PD and other types of parkinsonism in three elderly populations of central Spain
A11 01  1    @1 BENITO-LEON (Julian)
A11 02  1    @1 BERMEJO-PAREJA (Félix)
A11 03  1    @1 RODRIGUEZ (Javier)
A11 04  1    @1 MOLINA (José-Antonio)
A11 05  1    @1 GABRIEL (Rafael)
A11 06  1    @1 MORALES (José-Manuel)
A14 01      @1 Department of Neurology, Móstoles General Hospital @2 Móstoles, Madrid @3 ESP @Z 1 aut.
A14 02      @1 Department of Neurology, University Hospital 12 de Octubre @2 Madrid @3 ESP @Z 2 aut. @Z 4 aut.
A14 03      @1 Department of Neurology, Nuestra Sra. del Prado Hospital @2 Talavera de la Reina, Toledo @3 ESP @Z 3 aut.
A14 04      @1 Department of Epidemiology, University Hospital La Princesa @2 Madrid @3 ESP @Z 5 aut.
A14 05      @1 Department of Research, Ministry of Labor and Social Affairs @2 Madrid @3 ESP @Z 6 aut.
A17 01  1    @1 Neurological Disorders in Central Spain (NEDICES) Study Group @3 ESP
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A43 01      @1 INIST @2 20953 @5 354000109859510040
A44       @0 0000 @1 © 2003 INIST-CNRS. All rights reserved.
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C01 01    ENG  @0 The prevalence of Parkinson's disease (PD) and other types of parkinsonism in three elderly populations of central Spain was investigated using a door-to-door, two-phase approach. This design called for the administration of a brief questionnaire to subjects 65 years of age or older taken from the census of one urban municipality of Greater Madrid (Margaritas, Getafe), one rural site (Arévalo County, Ávila), and one urban district of Madrid (Lista) in Spain (N = 5,278). Study neurologists extensively investigated those subjects who screened positively. The diagnoses, based on specified criteria, were reviewed to increase reliability across neurologists. We found 118 subjects with parkinsonism: 81 affected by PD (68.6%), 26 drug-induced parkinsonism (22.0%), 6 parkinsonism in dementia (5.1%), 3 vascular parkinsonism (2.5%), and 2 unspecified parkinsonism (1.7%). The prevalence was 2.2% (95% confidence interval [CI], 1.8 -2.6) for all types of parkinsonism and 1.5% (95% CI, 1.2-1.8) for PD. The prevalence estimates of parkinsonism and PD increased with age, declining at 85 years and over. Age prevalence ratios were higher for men. Twenty-three subjects (28.4%) of the subjects with PD were detected through the screening and had not been diagnosed previously. Overall prevalence estimates of PD and other types of parkinsonism in central Spain rank at levels similar to those recently reported for other European and non-European elderly populations. Despite improvement in access to health services, an important proportion of PD patients may never seek neurological attention.
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Format Inist (serveur)

NO : PASCAL 03-0238136 INIST
ET : Prevalence of PD and other types of parkinsonism in three elderly populations of central Spain
AU : BENITO-LEON (Julian); BERMEJO-PAREJA (Félix); RODRIGUEZ (Javier); MOLINA (José-Antonio); GABRIEL (Rafael); MORALES (José-Manuel)
AF : Department of Neurology, Móstoles General Hospital/Móstoles, Madrid/Espagne (1 aut.); Department of Neurology, University Hospital 12 de Octubre/Madrid/Espagne (2 aut., 4 aut.); Department of Neurology, Nuestra Sra. del Prado Hospital/Talavera de la Reina, Toledo/Espagne (3 aut.); Department of Epidemiology, University Hospital La Princesa/Madrid/Espagne (5 aut.); Department of Research, Ministry of Labor and Social Affairs/Madrid/Espagne (6 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2003; Vol. 18; No. 3; Pp. 267-274; Bibl. 38 ref.
LA : Anglais
EA : The prevalence of Parkinson's disease (PD) and other types of parkinsonism in three elderly populations of central Spain was investigated using a door-to-door, two-phase approach. This design called for the administration of a brief questionnaire to subjects 65 years of age or older taken from the census of one urban municipality of Greater Madrid (Margaritas, Getafe), one rural site (Arévalo County, Ávila), and one urban district of Madrid (Lista) in Spain (N = 5,278). Study neurologists extensively investigated those subjects who screened positively. The diagnoses, based on specified criteria, were reviewed to increase reliability across neurologists. We found 118 subjects with parkinsonism: 81 affected by PD (68.6%), 26 drug-induced parkinsonism (22.0%), 6 parkinsonism in dementia (5.1%), 3 vascular parkinsonism (2.5%), and 2 unspecified parkinsonism (1.7%). The prevalence was 2.2% (95% confidence interval [CI], 1.8 -2.6) for all types of parkinsonism and 1.5% (95% CI, 1.2-1.8) for PD. The prevalence estimates of parkinsonism and PD increased with age, declining at 85 years and over. Age prevalence ratios were higher for men. Twenty-three subjects (28.4%) of the subjects with PD were detected through the screening and had not been diagnosed previously. Overall prevalence estimates of PD and other types of parkinsonism in central Spain rank at levels similar to those recently reported for other European and non-European elderly populations. Despite improvement in access to health services, an important proportion of PD patients may never seek neurological attention.
CC : 002B17G
FD : Parkinson maladie; Parkinsonisme; Espagne; Zone rurale; Zone urbaine; Prévalence; Epidémiologie; Personne âgée
FG : Europe; Homme; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Trouble neurologique; Santé publique
ED : Parkinson disease; Parkinsonism; Spain; Rural area; Urban area; Prevalence; Epidemiology; Elderly
EG : Europe; Human; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Neurological disorder; Public health
SD : Parkinson enfermedad; Parkinson síndrome; España; Zona rural; Zona urbana; Prevalencia; Epidemiología; Anciano
LO : INIST-20953.354000109859510040
ID : 03-0238136

Links to Exploration step

Pascal:03-0238136

Le document en format XML

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<s0>The prevalence of Parkinson's disease (PD) and other types of parkinsonism in three elderly populations of central Spain was investigated using a door-to-door, two-phase approach. This design called for the administration of a brief questionnaire to subjects 65 years of age or older taken from the census of one urban municipality of Greater Madrid (Margaritas, Getafe), one rural site (Arévalo County, Ávila), and one urban district of Madrid (Lista) in Spain (N = 5,278). Study neurologists extensively investigated those subjects who screened positively. The diagnoses, based on specified criteria, were reviewed to increase reliability across neurologists. We found 118 subjects with parkinsonism: 81 affected by PD (68.6%), 26 drug-induced parkinsonism (22.0%), 6 parkinsonism in dementia (5.1%), 3 vascular parkinsonism (2.5%), and 2 unspecified parkinsonism (1.7%). The prevalence was 2.2% (95% confidence interval [CI], 1.8 -2.6) for all types of parkinsonism and 1.5% (95% CI, 1.2-1.8) for PD. The prevalence estimates of parkinsonism and PD increased with age, declining at 85 years and over. Age prevalence ratios were higher for men. Twenty-three subjects (28.4%) of the subjects with PD were detected through the screening and had not been diagnosed previously. Overall prevalence estimates of PD and other types of parkinsonism in central Spain rank at levels similar to those recently reported for other European and non-European elderly populations. Despite improvement in access to health services, an important proportion of PD patients may never seek neurological attention.</s0>
</fC01>
<fC02 i1="01" i2="X">
<s0>002B17G</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Parkinson maladie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Parkinson disease</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Parkinson enfermedad</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Parkinsonisme</s0>
<s2>NM</s2>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Parkinsonism</s0>
<s2>NM</s2>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Parkinson síndrome</s0>
<s2>NM</s2>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Espagne</s0>
<s2>NG</s2>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Spain</s0>
<s2>NG</s2>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>España</s0>
<s2>NG</s2>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Zone rurale</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Rural area</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
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<s5>10</s5>
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<s5>11</s5>
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<fC03 i1="05" i2="X" l="ENG">
<s0>Urban area</s0>
<s5>11</s5>
</fC03>
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<s0>Zona urbana</s0>
<s5>11</s5>
</fC03>
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<s0>Prévalence</s0>
<s5>17</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Prevalence</s0>
<s5>17</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Prevalencia</s0>
<s5>17</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Epidémiologie</s0>
<s5>18</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Epidemiology</s0>
<s5>18</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Epidemiología</s0>
<s5>18</s5>
</fC03>
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<s0>Personne âgée</s0>
<s5>20</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Elderly</s0>
<s5>20</s5>
</fC03>
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<s0>Anciano</s0>
<s5>20</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Europe</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Europe</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Europa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Homme</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Human</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Hombre</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Système nerveux pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Nervous system diseases</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Sistema nervioso patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Système nerveux central pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Encéphale pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>41</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE">
<s0>Trouble neurologique</s0>
<s5>45</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>45</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>45</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE">
<s0>Santé publique</s0>
<s5>53</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG">
<s0>Public health</s0>
<s5>53</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA">
<s0>Salud pública</s0>
<s5>53</s5>
</fC07>
<fN21>
<s1>146</s1>
</fN21>
<fN82>
<s1>PSI</s1>
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<NO>PASCAL 03-0238136 INIST</NO>
<ET>Prevalence of PD and other types of parkinsonism in three elderly populations of central Spain</ET>
<AU>BENITO-LEON (Julian); BERMEJO-PAREJA (Félix); RODRIGUEZ (Javier); MOLINA (José-Antonio); GABRIEL (Rafael); MORALES (José-Manuel)</AU>
<AF>Department of Neurology, Móstoles General Hospital/Móstoles, Madrid/Espagne (1 aut.); Department of Neurology, University Hospital 12 de Octubre/Madrid/Espagne (2 aut., 4 aut.); Department of Neurology, Nuestra Sra. del Prado Hospital/Talavera de la Reina, Toledo/Espagne (3 aut.); Department of Epidemiology, University Hospital La Princesa/Madrid/Espagne (5 aut.); Department of Research, Ministry of Labor and Social Affairs/Madrid/Espagne (6 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2003; Vol. 18; No. 3; Pp. 267-274; Bibl. 38 ref.</SO>
<LA>Anglais</LA>
<EA>The prevalence of Parkinson's disease (PD) and other types of parkinsonism in three elderly populations of central Spain was investigated using a door-to-door, two-phase approach. This design called for the administration of a brief questionnaire to subjects 65 years of age or older taken from the census of one urban municipality of Greater Madrid (Margaritas, Getafe), one rural site (Arévalo County, Ávila), and one urban district of Madrid (Lista) in Spain (N = 5,278). Study neurologists extensively investigated those subjects who screened positively. The diagnoses, based on specified criteria, were reviewed to increase reliability across neurologists. We found 118 subjects with parkinsonism: 81 affected by PD (68.6%), 26 drug-induced parkinsonism (22.0%), 6 parkinsonism in dementia (5.1%), 3 vascular parkinsonism (2.5%), and 2 unspecified parkinsonism (1.7%). The prevalence was 2.2% (95% confidence interval [CI], 1.8 -2.6) for all types of parkinsonism and 1.5% (95% CI, 1.2-1.8) for PD. The prevalence estimates of parkinsonism and PD increased with age, declining at 85 years and over. Age prevalence ratios were higher for men. Twenty-three subjects (28.4%) of the subjects with PD were detected through the screening and had not been diagnosed previously. Overall prevalence estimates of PD and other types of parkinsonism in central Spain rank at levels similar to those recently reported for other European and non-European elderly populations. Despite improvement in access to health services, an important proportion of PD patients may never seek neurological attention.</EA>
<CC>002B17G</CC>
<FD>Parkinson maladie; Parkinsonisme; Espagne; Zone rurale; Zone urbaine; Prévalence; Epidémiologie; Personne âgée</FD>
<FG>Europe; Homme; Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Trouble neurologique; Santé publique</FG>
<ED>Parkinson disease; Parkinsonism; Spain; Rural area; Urban area; Prevalence; Epidemiology; Elderly</ED>
<EG>Europe; Human; Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Neurological disorder; Public health</EG>
<SD>Parkinson enfermedad; Parkinson síndrome; España; Zona rural; Zona urbana; Prevalencia; Epidemiología; Anciano</SD>
<LO>INIST-20953.354000109859510040</LO>
<ID>03-0238136</ID>
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