Sleepiness in Parkinson's disease: A controlled study
Identifieur interne : 002455 ( PascalFrancis/Corpus ); précédent : 002454; suivant : 002456Sleepiness in Parkinson's disease: A controlled study
Auteurs : Matthew A. Brodsky ; James Godbold ; Tom Roth ; C. Warren OlanowSource :
- Movement disorders [ 0885-3185 ] ; 2003.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Sudden-onset sleep episodes while driving have been reported in Parkinson's disease (PD) patients, and termed sleep attacks because they were reported to be irresistible and to occur without warning. We postulate that these episodes are due to excessive daytime sleepiness secondary to the high frequency of sleep disorders in PD patients and the sedative effects of dopaminergic medications. We assessed the frequency and relationship between excess daytime sleepiness and sleep episodes while driving (SE) in patients with PD. We evaluated 101 consecutive PD patients presenting to the Movement Disorder Center at the Mount Sinai School of Medicine using a questionnaire that incorporated a subjective estimate of sleepiness, the Epworth Sleepiness Scale (ESS) and information on disease severity and dopaminergic medications. One hundred age-matched respondents without PD served as a control population. Excess daytime sleepiness was reported in 76% of PD patients compared to 47% of controls (P < 0.05). The mean ESS scores for PD patients was 9.1 ± 6.1 versus 5.7 ± 4.4 in controls (P < 0.001). ESS scores ≥10 were observed in 40.6% of PD patients compared to 19% of controls (P < 0.01) and 24% of PD patients had scores ≥15, compared to 5% of controls (P < 0.001). Sleep episodes while driving were experienced by 20.8% of PD drivers compared to 6% of control drivers (P < 0.05). The mean daily levodopa (L-dopa) dose equivalent was 1.142 ± 858 mg in PD drivers who experienced a SE while driving compared to 626 ± 667 mg in those who had not (P < 0.05). Similarly, ESS was significantly greater in drivers with a SE than in those without (11.6 ± 6.4 vs. 8.4 ± 4.1; P < 0.05). Logistic regression analysis demonstrated that ESS and mean daily L-dopa dose equivalents were predictors of sleep episodes while driving, whereas age, gender, disease severity, and individual dopaminergic agents were not. These findings support the notion that sleep episodes while driving in PD patients are related to excess daytime sleepiness and dopaminergic load. Physicians should advise and treat patients accordingly.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
|
|---|
Format Inist (serveur)
| NO : | PASCAL 03-0380938 INIST |
|---|---|
| ET : | Sleepiness in Parkinson's disease: A controlled study |
| AU : | BRODSKY (Matthew A.); GODBOLD (James); ROTH (Tom); OLANOW (C. Warren) |
| AF : | Mount Sinai School of Medicine/New York, New York/Etats-Unis (1 aut., 2 aut., 4 aut.); Henry Ford Hospital/Detroit, Michigan/Etats-Unis (3 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2003; Vol. 18; No. 6; Pp. 668-672; Bibl. 33 ref. |
| LA : | Anglais |
| EA : | Sudden-onset sleep episodes while driving have been reported in Parkinson's disease (PD) patients, and termed sleep attacks because they were reported to be irresistible and to occur without warning. We postulate that these episodes are due to excessive daytime sleepiness secondary to the high frequency of sleep disorders in PD patients and the sedative effects of dopaminergic medications. We assessed the frequency and relationship between excess daytime sleepiness and sleep episodes while driving (SE) in patients with PD. We evaluated 101 consecutive PD patients presenting to the Movement Disorder Center at the Mount Sinai School of Medicine using a questionnaire that incorporated a subjective estimate of sleepiness, the Epworth Sleepiness Scale (ESS) and information on disease severity and dopaminergic medications. One hundred age-matched respondents without PD served as a control population. Excess daytime sleepiness was reported in 76% of PD patients compared to 47% of controls (P < 0.05). The mean ESS scores for PD patients was 9.1 ± 6.1 versus 5.7 ± 4.4 in controls (P < 0.001). ESS scores ≥10 were observed in 40.6% of PD patients compared to 19% of controls (P < 0.01) and 24% of PD patients had scores ≥15, compared to 5% of controls (P < 0.001). Sleep episodes while driving were experienced by 20.8% of PD drivers compared to 6% of control drivers (P < 0.05). The mean daily levodopa (L-dopa) dose equivalent was 1.142 ± 858 mg in PD drivers who experienced a SE while driving compared to 626 ± 667 mg in those who had not (P < 0.05). Similarly, ESS was significantly greater in drivers with a SE than in those without (11.6 ± 6.4 vs. 8.4 ± 4.1; P < 0.05). Logistic regression analysis demonstrated that ESS and mean daily L-dopa dose equivalents were predictors of sleep episodes while driving, whereas age, gender, disease severity, and individual dopaminergic agents were not. These findings support the notion that sleep episodes while driving in PD patients are related to excess daytime sleepiness and dopaminergic load. Physicians should advise and treat patients accordingly. |
| CC : | 002B17G |
| FD : | Parkinson maladie; Somnolence; Epidémiologie; Fréquence; Homme; Questionnaire; Epworth Sleepiness Scale |
| FG : | Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative |
| ED : | Parkinson disease; Somnolence; Epidemiology; Frequency; Human; Questionnaire |
| EG : | Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease |
| SD : | Parkinson enfermedad; Somnolencia; Epidemiología; Frecuencia; Hombre; Cuestionario |
| LO : | INIST-20953.354000119840860080 |
| ID : | 03-0380938 |
Links to Exploration step
Pascal:03-0380938Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Sleepiness in Parkinson's disease: A controlled study</title><author><name sortKey="Brodsky, Matthew A" sort="Brodsky, Matthew A" uniqKey="Brodsky M" first="Matthew A." last="Brodsky">Matthew A. Brodsky</name><affiliation><inist:fA14 i1="01"><s1>Mount Sinai School of Medicine</s1><s2>New York, New York</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Godbold, James" sort="Godbold, James" uniqKey="Godbold J" first="James" last="Godbold">James Godbold</name><affiliation><inist:fA14 i1="01"><s1>Mount Sinai School of Medicine</s1><s2>New York, New York</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Roth, Tom" sort="Roth, Tom" uniqKey="Roth T" first="Tom" last="Roth">Tom Roth</name><affiliation><inist:fA14 i1="02"><s1>Henry Ford Hospital</s1><s2>Detroit, Michigan</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Olanow, C Warren" sort="Olanow, C Warren" uniqKey="Olanow C" first="C. Warren" last="Olanow">C. Warren Olanow</name><affiliation><inist:fA14 i1="01"><s1>Mount Sinai School of Medicine</s1><s2>New York, New York</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">03-0380938</idno><date when="2003">2003</date><idno type="stanalyst">PASCAL 03-0380938 INIST</idno><idno type="RBID">Pascal:03-0380938</idno><idno type="wicri:Area/PascalFrancis/Corpus">002455</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Sleepiness in Parkinson's disease: A controlled study</title><author><name sortKey="Brodsky, Matthew A" sort="Brodsky, Matthew A" uniqKey="Brodsky M" first="Matthew A." last="Brodsky">Matthew A. Brodsky</name><affiliation><inist:fA14 i1="01"><s1>Mount Sinai School of Medicine</s1><s2>New York, New York</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Godbold, James" sort="Godbold, James" uniqKey="Godbold J" first="James" last="Godbold">James Godbold</name><affiliation><inist:fA14 i1="01"><s1>Mount Sinai School of Medicine</s1><s2>New York, New York</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Roth, Tom" sort="Roth, Tom" uniqKey="Roth T" first="Tom" last="Roth">Tom Roth</name><affiliation><inist:fA14 i1="02"><s1>Henry Ford Hospital</s1><s2>Detroit, Michigan</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Olanow, C Warren" sort="Olanow, C Warren" uniqKey="Olanow C" first="C. Warren" last="Olanow">C. Warren Olanow</name><affiliation><inist:fA14 i1="01"><s1>Mount Sinai School of Medicine</s1><s2>New York, New York</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2003">2003</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Epidemiology</term><term>Frequency</term><term>Human</term><term>Parkinson disease</term><term>Questionnaire</term><term>Somnolence</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term><term>Somnolence</term><term>Epidémiologie</term><term>Fréquence</term><term>Homme</term><term>Questionnaire</term><term>Epworth Sleepiness Scale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Sudden-onset sleep episodes while driving have been reported in Parkinson's disease (PD) patients, and termed sleep attacks because they were reported to be irresistible and to occur without warning. We postulate that these episodes are due to excessive daytime sleepiness secondary to the high frequency of sleep disorders in PD patients and the sedative effects of dopaminergic medications. We assessed the frequency and relationship between excess daytime sleepiness and sleep episodes while driving (SE) in patients with PD. We evaluated 101 consecutive PD patients presenting to the Movement Disorder Center at the Mount Sinai School of Medicine using a questionnaire that incorporated a subjective estimate of sleepiness, the Epworth Sleepiness Scale (ESS) and information on disease severity and dopaminergic medications. One hundred age-matched respondents without PD served as a control population. Excess daytime sleepiness was reported in 76% of PD patients compared to 47% of controls (P < 0.05). The mean ESS scores for PD patients was 9.1 ± 6.1 versus 5.7 ± 4.4 in controls (P < 0.001). ESS scores ≥10 were observed in 40.6% of PD patients compared to 19% of controls (P < 0.01) and 24% of PD patients had scores ≥15, compared to 5% of controls (P < 0.001). Sleep episodes while driving were experienced by 20.8% of PD drivers compared to 6% of control drivers (P < 0.05). The mean daily levodopa (L-dopa) dose equivalent was 1.142 ± 858 mg in PD drivers who experienced a SE while driving compared to 626 ± 667 mg in those who had not (P < 0.05). Similarly, ESS was significantly greater in drivers with a SE than in those without (11.6 ± 6.4 vs. 8.4 ± 4.1; P < 0.05). Logistic regression analysis demonstrated that ESS and mean daily L-dopa dose equivalents were predictors of sleep episodes while driving, whereas age, gender, disease severity, and individual dopaminergic agents were not. These findings support the notion that sleep episodes while driving in PD patients are related to excess daytime sleepiness and dopaminergic load. Physicians should advise and treat patients accordingly.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0></fA01><fA03 i2="1"><s0>Mov. disord.</s0></fA03><fA05><s2>18</s2></fA05><fA06><s2>6</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Sleepiness in Parkinson's disease: A controlled study</s1></fA08><fA11 i1="01" i2="1"><s1>BRODSKY (Matthew A.)</s1></fA11><fA11 i1="02" i2="1"><s1>GODBOLD (James)</s1></fA11><fA11 i1="03" i2="1"><s1>ROTH (Tom)</s1></fA11><fA11 i1="04" i2="1"><s1>OLANOW (C. Warren)</s1></fA11><fA14 i1="01"><s1>Mount Sinai School of Medicine</s1><s2>New York, New York</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ></fA14><fA14 i1="02"><s1>Henry Ford Hospital</s1><s2>Detroit, Michigan</s2><s3>USA</s3><sZ>3 aut.</sZ></fA14><fA20><s1>668-672</s1></fA20><fA21><s1>2003</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20953</s2><s5>354000119840860080</s5></fA43><fA44><s0>0000</s0><s1>© 2003 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>33 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>03-0380938</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Movement disorders</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Sudden-onset sleep episodes while driving have been reported in Parkinson's disease (PD) patients, and termed sleep attacks because they were reported to be irresistible and to occur without warning. We postulate that these episodes are due to excessive daytime sleepiness secondary to the high frequency of sleep disorders in PD patients and the sedative effects of dopaminergic medications. We assessed the frequency and relationship between excess daytime sleepiness and sleep episodes while driving (SE) in patients with PD. We evaluated 101 consecutive PD patients presenting to the Movement Disorder Center at the Mount Sinai School of Medicine using a questionnaire that incorporated a subjective estimate of sleepiness, the Epworth Sleepiness Scale (ESS) and information on disease severity and dopaminergic medications. One hundred age-matched respondents without PD served as a control population. Excess daytime sleepiness was reported in 76% of PD patients compared to 47% of controls (P < 0.05). The mean ESS scores for PD patients was 9.1 ± 6.1 versus 5.7 ± 4.4 in controls (P < 0.001). ESS scores ≥10 were observed in 40.6% of PD patients compared to 19% of controls (P < 0.01) and 24% of PD patients had scores ≥15, compared to 5% of controls (P < 0.001). Sleep episodes while driving were experienced by 20.8% of PD drivers compared to 6% of control drivers (P < 0.05). The mean daily levodopa (L-dopa) dose equivalent was 1.142 ± 858 mg in PD drivers who experienced a SE while driving compared to 626 ± 667 mg in those who had not (P < 0.05). Similarly, ESS was significantly greater in drivers with a SE than in those without (11.6 ± 6.4 vs. 8.4 ± 4.1; P < 0.05). Logistic regression analysis demonstrated that ESS and mean daily L-dopa dose equivalents were predictors of sleep episodes while driving, whereas age, gender, disease severity, and individual dopaminergic agents were not. These findings support the notion that sleep episodes while driving in PD patients are related to excess daytime sleepiness and dopaminergic load. Physicians should advise and treat patients accordingly.</s0></fC01><fC02 i1="01" i2="X"><s0>002B17G</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Parkinson maladie</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Parkinson enfermedad</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Somnolence</s0><s5>04</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Somnolence</s0><s5>04</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Somnolencia</s0><s5>04</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Epidémiologie</s0><s5>17</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Epidemiology</s0><s5>17</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Epidemiología</s0><s5>17</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Fréquence</s0><s5>18</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Frequency</s0><s5>18</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Frecuencia</s0><s5>18</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Homme</s0><s5>20</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Human</s0><s5>20</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Hombre</s0><s5>20</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Questionnaire</s0><s5>21</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Questionnaire</s0><s5>21</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Cuestionario</s0><s5>21</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Epworth Sleepiness Scale</s0><s4>INC</s4><s5>86</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Central nervous system disease</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Encéphale pathologie</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Cerebral disorder</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Encéfalo patología</s0><s5>39</s5></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0><s5>40</s5></fC07><fC07 i1="05" i2="X" l="FRE"><s0>Maladie dégénérative</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="ENG"><s0>Degenerative disease</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0><s5>41</s5></fC07><fN21><s1>265</s1></fN21><fN82><s1>PSI</s1></fN82></pA></standard><server><NO>PASCAL 03-0380938 INIST</NO><ET>Sleepiness in Parkinson's disease: A controlled study</ET><AU>BRODSKY (Matthew A.); GODBOLD (James); ROTH (Tom); OLANOW (C. Warren)</AU><AF>Mount Sinai School of Medicine/New York, New York/Etats-Unis (1 aut., 2 aut., 4 aut.); Henry Ford Hospital/Detroit, Michigan/Etats-Unis (3 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2003; Vol. 18; No. 6; Pp. 668-672; Bibl. 33 ref.</SO><LA>Anglais</LA><EA>Sudden-onset sleep episodes while driving have been reported in Parkinson's disease (PD) patients, and termed sleep attacks because they were reported to be irresistible and to occur without warning. We postulate that these episodes are due to excessive daytime sleepiness secondary to the high frequency of sleep disorders in PD patients and the sedative effects of dopaminergic medications. We assessed the frequency and relationship between excess daytime sleepiness and sleep episodes while driving (SE) in patients with PD. We evaluated 101 consecutive PD patients presenting to the Movement Disorder Center at the Mount Sinai School of Medicine using a questionnaire that incorporated a subjective estimate of sleepiness, the Epworth Sleepiness Scale (ESS) and information on disease severity and dopaminergic medications. One hundred age-matched respondents without PD served as a control population. Excess daytime sleepiness was reported in 76% of PD patients compared to 47% of controls (P < 0.05). The mean ESS scores for PD patients was 9.1 ± 6.1 versus 5.7 ± 4.4 in controls (P < 0.001). ESS scores ≥10 were observed in 40.6% of PD patients compared to 19% of controls (P < 0.01) and 24% of PD patients had scores ≥15, compared to 5% of controls (P < 0.001). Sleep episodes while driving were experienced by 20.8% of PD drivers compared to 6% of control drivers (P < 0.05). The mean daily levodopa (L-dopa) dose equivalent was 1.142 ± 858 mg in PD drivers who experienced a SE while driving compared to 626 ± 667 mg in those who had not (P < 0.05). Similarly, ESS was significantly greater in drivers with a SE than in those without (11.6 ± 6.4 vs. 8.4 ± 4.1; P < 0.05). Logistic regression analysis demonstrated that ESS and mean daily L-dopa dose equivalents were predictors of sleep episodes while driving, whereas age, gender, disease severity, and individual dopaminergic agents were not. These findings support the notion that sleep episodes while driving in PD patients are related to excess daytime sleepiness and dopaminergic load. Physicians should advise and treat patients accordingly.</EA><CC>002B17G</CC><FD>Parkinson maladie; Somnolence; Epidémiologie; Fréquence; Homme; Questionnaire; Epworth Sleepiness Scale</FD><FG>Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative</FG><ED>Parkinson disease; Somnolence; Epidemiology; Frequency; Human; Questionnaire</ED><EG>Nervous system diseases; Central nervous system disease; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease</EG><SD>Parkinson enfermedad; Somnolencia; Epidemiología; Frecuencia; Hombre; Cuestionario</SD><LO>INIST-20953.354000119840860080</LO><ID>03-0380938</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002455 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 002455 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:03-0380938
|texte= Sleepiness in Parkinson's disease: A controlled study
}}
| This area was generated with Dilib version V0.6.23. |  |