MovDisordV3, PascalFrancis, Corpus, bibRecord, 002044

Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT

Identifieur interne : 002044 ( PascalFrancis/Corpus ); précédent : 002043; suivant : 002045

Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT

Auteurs : Ulrike Sommer ; Thomas Hummel ; Katja Cormann ; Antje Mueller ; Johannes Frasnelli ; Joachim Kropp ; Heinz Reichmann

Source :

Movement disorders [ 0885-3185 ] ; 2004.

RBID : Pascal:04-0581921

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Dépistage, Exploration ultrason, Parkinson maladie, Tomoscintigraphie émission monophotonique, Photon.

English descriptors

KwdEn :
- Medical screening, Nervous system diseases, Parkinson disease, Photon, Single photon emission tomography, Sonography.

Abstract

Olfactory loss is among the early signs of Parkinson's disease (PD). We investigated whether "idiopathic" olfactory dysfunction might relate to signs of nigral degeneration. Olfactory tests were combined with transcranial sonography of the substantia nigra and single photon emission computed tomography (SPECT) imaging. Thirty patients diagnosed with idiopathic olfactory loss participated. Eleven of these patients exhibited an increased echogenicity of the SN in the transcranial sonography. In 10 of these 11 patients, SPECT scans with ¹²³I-FP-CIT were performed. Median uptake ratios in the basal ganglia were pathological in 5 patients, 2 patients exhibited borderline findings, and 3 patients had normal results. Considering patients with idiopathic olfactory dysfunction, noninvasive transcranial sonography seems to be helpful in identifying patients potentially at risk to develop PD. Longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop PD in the future.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0885-3185`
A03		`1`		`@0 Mov. disord.`
A05				`@2 19`
A06				`@2 10`
A08	`01`	`1`	`ENG`	`@1 Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT`
A11	`01`	`1`		`@1 SOMMER (Ulrike)`
A11	`02`	`1`		`@1 HUMMEL (Thomas)`
A11	`03`	`1`		`@1 CORMANN (Katja)`
A11	`04`	`1`		`@1 MUELLER (Antje)`
A11	`05`	`1`		`@1 FRASNELLI (Johannes)`
A11	`06`	`1`		`@1 KROPP (Joachim)`
A11	`07`	`1`		`@1 REICHMANN (Heinz)`
A14	`01`			`@1 Department of Neurology, University of Dresden Medical School @2 Dresden @3 DEU @Z 1 aut. @Z 3 aut. @Z 4 aut. @Z 7 aut.`
A14	`02`			`@1 Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School @2 Dresden @3 DEU @Z 2 aut. @Z 5 aut.`
A14	`03`			`@1 Institute of Nuclear Medicine, University of Dresden Medical School @2 Dresden @3 DEU @Z 6 aut.`
A20				`@1 1196-1202`
A21				`@1 2004`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000122474340100`
A44				`@0 0000 @1 © 2004 INIST-CNRS. All rights reserved.`
A45				`@0 53 ref.`
A47	`01`	`1`		`@0 04-0581921`
A60				`@1 P @3 CC`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Olfactory loss is among the early signs of Parkinson's disease (PD). We investigated whether "idiopathic" olfactory dysfunction might relate to signs of nigral degeneration. Olfactory tests were combined with transcranial sonography of the substantia nigra and single photon emission computed tomography (SPECT) imaging. Thirty patients diagnosed with idiopathic olfactory loss participated. Eleven of these patients exhibited an increased echogenicity of the SN in the transcranial sonography. In 10 of these 11 patients, SPECT scans with ¹²³I-FP-CIT were performed. Median uptake ratios in the basal ganglia were pathological in 5 patients, 2 patients exhibited borderline findings, and 3 patients had normal results. Considering patients with idiopathic olfactory dysfunction, noninvasive transcranial sonography seems to be helpful in identifying patients potentially at risk to develop PD. Longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop PD in the future.
C02	`01`	`X`		`@0 002B17`
C02	`02`	`X`		`@0 002B17G`
C02	`03`	`X`		`@0 002B17A03`
C03	`01`	`X`	`FRE`	`@0 Système nerveux pathologie @5 01`
C03	`01`	`X`	`ENG`	`@0 Nervous system diseases @5 01`
C03	`01`	`X`	`SPA`	`@0 Sistema nervioso patología @5 01`
C03	`02`	`X`	`FRE`	`@0 Dépistage @5 02`
C03	`02`	`X`	`ENG`	`@0 Medical screening @5 02`
C03	`02`	`X`	`SPA`	`@0 Descubrimiento @5 02`
C03	`03`	`X`	`FRE`	`@0 Exploration ultrason @5 03`
C03	`03`	`X`	`ENG`	`@0 Sonography @5 03`
C03	`03`	`X`	`SPA`	`@0 Exploración ultrasonido @5 03`
C03	`04`	`X`	`FRE`	`@0 Parkinson maladie @5 04`
C03	`04`	`X`	`ENG`	`@0 Parkinson disease @5 04`
C03	`04`	`X`	`SPA`	`@0 Parkinson enfermedad @5 04`
C03	`05`	`X`	`FRE`	`@0 Tomoscintigraphie émission monophotonique @5 05`
C03	`05`	`X`	`ENG`	`@0 Single photon emission tomography @5 05`
C03	`05`	`X`	`SPA`	`@0 Tomografía emisión fotón único @5 05`
C03	`06`	`X`	`FRE`	`@0 Photon @5 06`
C03	`06`	`X`	`ENG`	`@0 Photon @5 06`
C03	`06`	`X`	`SPA`	`@0 Fotón @5 06`
C07	`01`	`X`	`FRE`	`@0 Encéphale pathologie @5 37`
C07	`01`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`01`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 38`
C07	`03`	`X`	`FRE`	`@0 Maladie dégénérative @5 39`
C07	`03`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
C07	`04`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 40`
C07	`04`	`X`	`ENG`	`@0 Central nervous system disease @5 40`
C07	`04`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 40`
C07	`05`	`X`	`FRE`	`@0 Exploration radioisotopique @5 41`
C07	`05`	`X`	`ENG`	`@0 Radionuclide study @5 41`
C07	`05`	`X`	`SPA`	`@0 Exploración radioisotópica @5 41`
N21				`@1 334`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 04-0581921 INIST
ET :	Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT
AU :	SOMMER (Ulrike); HUMMEL (Thomas); CORMANN (Katja); MUELLER (Antje); FRASNELLI (Johannes); KROPP (Joachim); REICHMANN (Heinz)
AF :	Department of Neurology, University of Dresden Medical School/Dresden/Allemagne (1 aut., 3 aut., 4 aut., 7 aut.); Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School/Dresden/Allemagne (2 aut., 5 aut.); Institute of Nuclear Medicine, University of Dresden Medical School/Dresden/Allemagne (6 aut.)
DT :	Publication en série; Courte communication, note brève; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2004; Vol. 19; No. 10; Pp. 1196-1202; Bibl. 53 ref.
LA :	Anglais
EA :	Olfactory loss is among the early signs of Parkinson's disease (PD). We investigated whether "idiopathic" olfactory dysfunction might relate to signs of nigral degeneration. Olfactory tests were combined with transcranial sonography of the substantia nigra and single photon emission computed tomography (SPECT) imaging. Thirty patients diagnosed with idiopathic olfactory loss participated. Eleven of these patients exhibited an increased echogenicity of the SN in the transcranial sonography. In 10 of these 11 patients, SPECT scans with ¹²³I-FP-CIT were performed. Median uptake ratios in the basal ganglia were pathological in 5 patients, 2 patients exhibited borderline findings, and 3 patients had normal results. Considering patients with idiopathic olfactory dysfunction, noninvasive transcranial sonography seems to be helpful in identifying patients potentially at risk to develop PD. Longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop PD in the future.
CC :	002B17; 002B17G; 002B17A03
FD :	Système nerveux pathologie; Dépistage; Exploration ultrason; Parkinson maladie; Tomoscintigraphie émission monophotonique; Photon
FG :	Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Exploration radioisotopique
ED :	Nervous system diseases; Medical screening; Sonography; Parkinson disease; Single photon emission tomography; Photon
EG :	Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Radionuclide study
SD :	Sistema nervioso patología; Descubrimiento; Exploración ultrasonido; Parkinson enfermedad; Tomografía emisión fotón único; Fotón
LO :	INIST-20953.354000122474340100
ID :	04-0581921

Links to Exploration step

Pascal:04-0581921

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT</title>
<author><name sortKey="Sommer, Ulrike" sort="Sommer, Ulrike" uniqKey="Sommer U" first="Ulrike" last="Sommer">Ulrike Sommer</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Hummel, Thomas" sort="Hummel, Thomas" uniqKey="Hummel T" first="Thomas" last="Hummel">Thomas Hummel</name>
<affiliation><inist:fA14 i1="02"><s1>Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Cormann, Katja" sort="Cormann, Katja" uniqKey="Cormann K" first="Katja" last="Cormann">Katja Cormann</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Mueller, Antje" sort="Mueller, Antje" uniqKey="Mueller A" first="Antje" last="Mueller">Antje Mueller</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Frasnelli, Johannes" sort="Frasnelli, Johannes" uniqKey="Frasnelli J" first="Johannes" last="Frasnelli">Johannes Frasnelli</name>
<affiliation><inist:fA14 i1="02"><s1>Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Kropp, Joachim" sort="Kropp, Joachim" uniqKey="Kropp J" first="Joachim" last="Kropp">Joachim Kropp</name>
<affiliation><inist:fA14 i1="03"><s1>Institute of Nuclear Medicine, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">04-0581921</idno>
<date when="2004">2004</date>
<idno type="stanalyst">PASCAL 04-0581921 INIST</idno>
<idno type="RBID">Pascal:04-0581921</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">002044</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT</title>
<author><name sortKey="Sommer, Ulrike" sort="Sommer, Ulrike" uniqKey="Sommer U" first="Ulrike" last="Sommer">Ulrike Sommer</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Hummel, Thomas" sort="Hummel, Thomas" uniqKey="Hummel T" first="Thomas" last="Hummel">Thomas Hummel</name>
<affiliation><inist:fA14 i1="02"><s1>Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Cormann, Katja" sort="Cormann, Katja" uniqKey="Cormann K" first="Katja" last="Cormann">Katja Cormann</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Mueller, Antje" sort="Mueller, Antje" uniqKey="Mueller A" first="Antje" last="Mueller">Antje Mueller</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Frasnelli, Johannes" sort="Frasnelli, Johannes" uniqKey="Frasnelli J" first="Johannes" last="Frasnelli">Johannes Frasnelli</name>
<affiliation><inist:fA14 i1="02"><s1>Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Kropp, Joachim" sort="Kropp, Joachim" uniqKey="Kropp J" first="Joachim" last="Kropp">Joachim Kropp</name>
<affiliation><inist:fA14 i1="03"><s1>Institute of Nuclear Medicine, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Reichmann, Heinz" sort="Reichmann, Heinz" uniqKey="Reichmann H" first="Heinz" last="Reichmann">Heinz Reichmann</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2004">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Medical screening</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Photon</term>
<term>Single photon emission tomography</term>
<term>Sonography</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Dépistage</term>
<term>Exploration ultrason</term>
<term>Parkinson maladie</term>
<term>Tomoscintigraphie émission monophotonique</term>
<term>Photon</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Olfactory loss is among the early signs of Parkinson's disease (PD). We investigated whether "idiopathic" olfactory dysfunction might relate to signs of nigral degeneration. Olfactory tests were combined with transcranial sonography of the substantia nigra and single photon emission computed tomography (SPECT) imaging. Thirty patients diagnosed with idiopathic olfactory loss participated. Eleven of these patients exhibited an increased echogenicity of the SN in the transcranial sonography. In 10 of these 11 patients, SPECT scans with <sup>123</sup>
I-FP-CIT were performed. Median uptake ratios in the basal ganglia were pathological in 5 patients, 2 patients exhibited borderline findings, and 3 patients had normal results. Considering patients with idiopathic olfactory dysfunction, noninvasive transcranial sonography seems to be helpful in identifying patients potentially at risk to develop PD. Longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop PD in the future.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0>
</fA01>
<fA03 i2="1"><s0>Mov. disord.</s0>
</fA03>
<fA05><s2>19</s2>
</fA05>
<fA06><s2>10</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>SOMMER (Ulrike)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>HUMMEL (Thomas)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>CORMANN (Katja)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>MUELLER (Antje)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>FRASNELLI (Johannes)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>KROPP (Joachim)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>REICHMANN (Heinz)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Neurology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Institute of Nuclear Medicine, University of Dresden Medical School</s1>
<s2>Dresden</s2>
<s3>DEU</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA20><s1>1196-1202</s1>
</fA20>
<fA21><s1>2004</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>20953</s2>
<s5>354000122474340100</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2004 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>53 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>04-0581921</s0>
</fA47>
<fA60><s1>P</s1>
<s3>CC</s3>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Movement disorders</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Olfactory loss is among the early signs of Parkinson's disease (PD). We investigated whether "idiopathic" olfactory dysfunction might relate to signs of nigral degeneration. Olfactory tests were combined with transcranial sonography of the substantia nigra and single photon emission computed tomography (SPECT) imaging. Thirty patients diagnosed with idiopathic olfactory loss participated. Eleven of these patients exhibited an increased echogenicity of the SN in the transcranial sonography. In 10 of these 11 patients, SPECT scans with <sup>123</sup>
I-FP-CIT were performed. Median uptake ratios in the basal ganglia were pathological in 5 patients, 2 patients exhibited borderline findings, and 3 patients had normal results. Considering patients with idiopathic olfactory dysfunction, noninvasive transcranial sonography seems to be helpful in identifying patients potentially at risk to develop PD. Longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop PD in the future.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B17G</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002B17A03</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Dépistage</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Medical screening</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Descubrimiento</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Exploration ultrason</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Sonography</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Exploración ultrasonido</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Parkinson maladie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Parkinson disease</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Parkinson enfermedad</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Tomoscintigraphie émission monophotonique</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Single photon emission tomography</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Tomografía emisión fotón único</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Photon</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Photon</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Fotón</s0>
<s5>06</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Exploration radioisotopique</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Radionuclide study</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Exploración radioisotópica</s0>
<s5>41</s5>
</fC07>
<fN21><s1>334</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 04-0581921 INIST</NO>
<ET>Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT</ET>
<AU>SOMMER (Ulrike); HUMMEL (Thomas); CORMANN (Katja); MUELLER (Antje); FRASNELLI (Johannes); KROPP (Joachim); REICHMANN (Heinz)</AU>
<AF>Department of Neurology, University of Dresden Medical School/Dresden/Allemagne (1 aut., 3 aut., 4 aut., 7 aut.); Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School/Dresden/Allemagne (2 aut., 5 aut.); Institute of Nuclear Medicine, University of Dresden Medical School/Dresden/Allemagne (6 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2004; Vol. 19; No. 10; Pp. 1196-1202; Bibl. 53 ref.</SO>
<LA>Anglais</LA>
<EA>Olfactory loss is among the early signs of Parkinson's disease (PD). We investigated whether "idiopathic" olfactory dysfunction might relate to signs of nigral degeneration. Olfactory tests were combined with transcranial sonography of the substantia nigra and single photon emission computed tomography (SPECT) imaging. Thirty patients diagnosed with idiopathic olfactory loss participated. Eleven of these patients exhibited an increased echogenicity of the SN in the transcranial sonography. In 10 of these 11 patients, SPECT scans with <sup>123</sup>
I-FP-CIT were performed. Median uptake ratios in the basal ganglia were pathological in 5 patients, 2 patients exhibited borderline findings, and 3 patients had normal results. Considering patients with idiopathic olfactory dysfunction, noninvasive transcranial sonography seems to be helpful in identifying patients potentially at risk to develop PD. Longitudinal follow-up studies are necessary to estimate the ratio of patients with dopaminergic cell loss in the basal ganglia who will develop PD in the future.</EA>
<CC>002B17; 002B17G; 002B17A03</CC>
<FD>Système nerveux pathologie; Dépistage; Exploration ultrason; Parkinson maladie; Tomoscintigraphie émission monophotonique; Photon</FD>
<FG>Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Exploration radioisotopique</FG>
<ED>Nervous system diseases; Medical screening; Sonography; Parkinson disease; Single photon emission tomography; Photon</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Radionuclide study</EG>
<SD>Sistema nervioso patología; Descubrimiento; Exploración ultrasonido; Parkinson enfermedad; Tomografía emisión fotón único; Fotón</SD>
<LO>INIST-20953.354000122474340100</LO>
<ID>04-0581921</ID>
</server>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002044 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 002044 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    PascalFrancis
   |étape=   Corpus
   |type=    RBID
   |clé=     Pascal:04-0581921
   |texte=   Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT
}}

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT

Detection of presymptomatic Parkinson's disease: Combining smell tests, transcranial sonography, and SPECT

Source :

Descripteurs français

English descriptors

Abstract

Notice en format standard (ISO 2709)

Format Inist (serveur)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri