Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)
Identifieur interne : 002005 ( PascalFrancis/Corpus ); précédent : 002004; suivant : 002006Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)
Auteurs : Gregor K. Wenning ; Francois Tison ; Klaus Seppi ; Cristina Sampaio ; Anja Diem ; Farid Yekhlef ; Imad Ghorayeb ; Fabienne Ory ; Monique Galitzky ; Tommaso Scaravilli ; Maria Bozi ; Carlo Colosimo ; Sid Gilman ; Clifford W. Shults ; Niall P. Quinn ; Olivier Rascol ; Werner PoeweSource :
- Movement disorders [ 0885-3185 ] ; 2004.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
We aimed to develop and validate a novel rating scale for multiple system atrophy (Unified Multiple System Atrophy Rating Scale - UMSARS). The scale comprises the following components: Part I, historical, 12 items; Part II, motor examination, 14 items; Part III, autonomic examination; and Part IV, global disability scale. For validation purposes, 40 MSA patients were assessed in four centers by 4 raters per center (2 senior and 2 junior raters). The raters applied the UMSARS, as well as a range of other scales, including the Unified Parkinson's Disease Rating Scale (UPDRS) and the International Cooperative Ataxia Rating Scale (ICARS). Internal consistency was high for both UMSARS-I (Crohnbach's alpha = 0.84) and UMSARS-II (Crohnbach's alpha = 0.90) sections. The interrater reliability of most of the UMSARS-I and -II items as well as of total UMSARS-I and -II subscores was substantial (k (w) = 0.6-0.8) to excellent (k (w) > 0.8). UMSARS-II correlated well with UPDRS-III and ICARS (rs > 0.8). Depending on the degree of the patient's disability, completion of the entire UMSARS took 30 to 45 minutes. Based on our findings, the UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 05-0069706 INIST |
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ET : | Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS) |
AU : | WENNING (Gregor K.); TISON (Francois); SEPPI (Klaus); SAMPAIO (Cristina); DIEM (Anja); YEKHLEF (Farid); GHORAYEB (Imad); ORY (Fabienne); GALITZKY (Monique); SCARAVILLI (Tommaso); BOZI (Maria); COLOSIMO (Carlo); GILMAN (Sid); SHULTS (Clifford W.); QUINN (Niall P.); RASCOL (Olivier); POEWE (Werner) |
AF : | Department of Neurology, University of Innsbruck/Innsbruck/Autriche (1 aut., 3 aut., 5 aut., 17 aut.); Service de Neurologie, Hopital du Haut-Leveque/Pessac/France (2 aut., 6 aut., 7 aut.); Faculdade de Medicine de Lisboa, Hospital Santa Maria, Centro de Neurosciencas/Lisboa/Portugal (4 aut.); Toulouse III University, Laboratoire de Phannacologie, Faculte de Medecine/Toulouse/France (8 aut., 9 aut., 16 aut.); University College London, Institute of Neurology, Queen Square/London/Royaume-Uni (10 aut., 11 aut., 15 aut.); Dipartimento di Scienze Neurologiche, Universita'La Sapienza/Rome/Italie (12 aut.); Department of Neurology, University of Michigan/Ann Arbor, Michigan/Etats-Unis (13 aut.); Department of Neurosciences, University of California San Diego School of Medicine, La Jolla/California/Etats-Unis (14 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2004; Vol. 19; No. 12; Pp. 1391-1402; Bibl. 31 ref. |
LA : | Anglais |
EA : | We aimed to develop and validate a novel rating scale for multiple system atrophy (Unified Multiple System Atrophy Rating Scale - UMSARS). The scale comprises the following components: Part I, historical, 12 items; Part II, motor examination, 14 items; Part III, autonomic examination; and Part IV, global disability scale. For validation purposes, 40 MSA patients were assessed in four centers by 4 raters per center (2 senior and 2 junior raters). The raters applied the UMSARS, as well as a range of other scales, including the Unified Parkinson's Disease Rating Scale (UPDRS) and the International Cooperative Ataxia Rating Scale (ICARS). Internal consistency was high for both UMSARS-I (Crohnbach's alpha = 0.84) and UMSARS-II (Crohnbach's alpha = 0.90) sections. The interrater reliability of most of the UMSARS-I and -II items as well as of total UMSARS-I and -II subscores was substantial (k (w) = 0.6-0.8) to excellent (k (w) > 0.8). UMSARS-II correlated well with UPDRS-III and ICARS (rs > 0.8). Depending on the degree of the patient's disability, completion of the entire UMSARS took 30 to 45 minutes. Based on our findings, the UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients. |
CC : | 002B17; 002B17F; 002B17G |
FD : | Système nerveux pathologie; Validation; Echelle d'évaluation; Atrophie multisystématisée |
ED : | Nervous system diseases; Validation; Evaluation scale; Multiple system atrophy |
SD : | Sistema nervioso patología; Validación; Escala evaluación; Atrofia multisistematizada |
LO : | INIST-20953.354000125735400010 |
ID : | 05-0069706 |
Links to Exploration step
Pascal:05-0069706Le document en format XML
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<front><div type="abstract" xml:lang="en">We aimed to develop and validate a novel rating scale for multiple system atrophy (Unified Multiple System Atrophy Rating Scale - UMSARS). The scale comprises the following components: Part I, historical, 12 items; Part II, motor examination, 14 items; Part III, autonomic examination; and Part IV, global disability scale. For validation purposes, 40 MSA patients were assessed in four centers by 4 raters per center (2 senior and 2 junior raters). The raters applied the UMSARS, as well as a range of other scales, including the Unified Parkinson's Disease Rating Scale (UPDRS) and the International Cooperative Ataxia Rating Scale (ICARS). Internal consistency was high for both UMSARS-I (Crohnbach's alpha = 0.84) and UMSARS-II (Crohnbach's alpha = 0.90) sections. The interrater reliability of most of the UMSARS-I and -II items as well as of total UMSARS-I and -II subscores was substantial (k (w) = 0.6-0.8) to excellent (k (w) > 0.8). UMSARS-II correlated well with UPDRS-III and ICARS (r<sub>s</sub>
> 0.8). Depending on the degree of the patient's disability, completion of the entire UMSARS took 30 to 45 minutes. Based on our findings, the UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients.</div>
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<fA08 i1="01" i2="1" l="ENG"><s1>Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)</s1>
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<fA11 i1="14" i2="1"><s1>SHULTS (Clifford W.)</s1>
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<fA11 i1="17" i2="1"><s1>POEWE (Werner)</s1>
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<fA14 i1="01"><s1>Department of Neurology, University of Innsbruck</s1>
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<sZ>3 aut.</sZ>
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<fA14 i1="02"><s1>Service de Neurologie, Hopital du Haut-Leveque</s1>
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<s3>FRA</s3>
<sZ>2 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
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<fA14 i1="03"><s1>Faculdade de Medicine de Lisboa, Hospital Santa Maria, Centro de Neurosciencas</s1>
<s2>Lisboa</s2>
<s3>PRT</s3>
<sZ>4 aut.</sZ>
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<fA14 i1="04"><s1>Toulouse III University, Laboratoire de Phannacologie, Faculte de Medecine</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>16 aut.</sZ>
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<fA14 i1="05"><s1>University College London, Institute of Neurology, Queen Square</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>15 aut.</sZ>
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<fA14 i1="06"><s1>Dipartimento di Scienze Neurologiche, Universita'La Sapienza</s1>
<s2>Rome</s2>
<s3>ITA</s3>
<sZ>12 aut.</sZ>
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<fA14 i1="07"><s1>Department of Neurology, University of Michigan</s1>
<s2>Ann Arbor, Michigan</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>Department of Neurosciences, University of California San Diego School of Medicine, La Jolla</s1>
<s2>California</s2>
<s3>USA</s3>
<sZ>14 aut.</sZ>
</fA14>
<fA17 i1="01" i2="1"><s1>Multiple System Atrophy Study Group</s1>
<s3>INC</s3>
</fA17>
<fA20><s1>1391-1402</s1>
</fA20>
<fA21><s1>2004</s1>
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<fA60><s1>P</s1>
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<fA66 i1="01"><s0>USA</s0>
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<fC01 i1="01" l="ENG"><s0>We aimed to develop and validate a novel rating scale for multiple system atrophy (Unified Multiple System Atrophy Rating Scale - UMSARS). The scale comprises the following components: Part I, historical, 12 items; Part II, motor examination, 14 items; Part III, autonomic examination; and Part IV, global disability scale. For validation purposes, 40 MSA patients were assessed in four centers by 4 raters per center (2 senior and 2 junior raters). The raters applied the UMSARS, as well as a range of other scales, including the Unified Parkinson's Disease Rating Scale (UPDRS) and the International Cooperative Ataxia Rating Scale (ICARS). Internal consistency was high for both UMSARS-I (Crohnbach's alpha = 0.84) and UMSARS-II (Crohnbach's alpha = 0.90) sections. The interrater reliability of most of the UMSARS-I and -II items as well as of total UMSARS-I and -II subscores was substantial (k (w) = 0.6-0.8) to excellent (k (w) > 0.8). UMSARS-II correlated well with UPDRS-III and ICARS (r<sub>s</sub>
> 0.8). Depending on the degree of the patient's disability, completion of the entire UMSARS took 30 to 45 minutes. Based on our findings, the UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients.</s0>
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<fC02 i1="01" i2="X"><s0>002B17</s0>
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<fC02 i1="02" i2="X"><s0>002B17F</s0>
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<fC02 i1="03" i2="X"><s0>002B17G</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>01</s5>
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<fC03 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>01</s5>
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<fC03 i1="02" i2="X" l="FRE"><s0>Validation</s0>
<s5>02</s5>
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<fC03 i1="02" i2="X" l="ENG"><s0>Validation</s0>
<s5>02</s5>
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<fC03 i1="03" i2="X" l="FRE"><s0>Echelle d'évaluation</s0>
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<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Atrophie multisystématisée</s0>
<s2>NM</s2>
<s5>04</s5>
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<fC03 i1="04" i2="X" l="ENG"><s0>Multiple system atrophy</s0>
<s2>NM</s2>
<s5>04</s5>
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<fC03 i1="04" i2="X" l="SPA"><s0>Atrofia multisistematizada</s0>
<s2>NM</s2>
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<fN21><s1>038</s1>
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<server><NO>PASCAL 05-0069706 INIST</NO>
<ET>Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)</ET>
<AU>WENNING (Gregor K.); TISON (Francois); SEPPI (Klaus); SAMPAIO (Cristina); DIEM (Anja); YEKHLEF (Farid); GHORAYEB (Imad); ORY (Fabienne); GALITZKY (Monique); SCARAVILLI (Tommaso); BOZI (Maria); COLOSIMO (Carlo); GILMAN (Sid); SHULTS (Clifford W.); QUINN (Niall P.); RASCOL (Olivier); POEWE (Werner)</AU>
<AF>Department of Neurology, University of Innsbruck/Innsbruck/Autriche (1 aut., 3 aut., 5 aut., 17 aut.); Service de Neurologie, Hopital du Haut-Leveque/Pessac/France (2 aut., 6 aut., 7 aut.); Faculdade de Medicine de Lisboa, Hospital Santa Maria, Centro de Neurosciencas/Lisboa/Portugal (4 aut.); Toulouse III University, Laboratoire de Phannacologie, Faculte de Medecine/Toulouse/France (8 aut., 9 aut., 16 aut.); University College London, Institute of Neurology, Queen Square/London/Royaume-Uni (10 aut., 11 aut., 15 aut.); Dipartimento di Scienze Neurologiche, Universita'La Sapienza/Rome/Italie (12 aut.); Department of Neurology, University of Michigan/Ann Arbor, Michigan/Etats-Unis (13 aut.); Department of Neurosciences, University of California San Diego School of Medicine, La Jolla/California/Etats-Unis (14 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2004; Vol. 19; No. 12; Pp. 1391-1402; Bibl. 31 ref.</SO>
<LA>Anglais</LA>
<EA>We aimed to develop and validate a novel rating scale for multiple system atrophy (Unified Multiple System Atrophy Rating Scale - UMSARS). The scale comprises the following components: Part I, historical, 12 items; Part II, motor examination, 14 items; Part III, autonomic examination; and Part IV, global disability scale. For validation purposes, 40 MSA patients were assessed in four centers by 4 raters per center (2 senior and 2 junior raters). The raters applied the UMSARS, as well as a range of other scales, including the Unified Parkinson's Disease Rating Scale (UPDRS) and the International Cooperative Ataxia Rating Scale (ICARS). Internal consistency was high for both UMSARS-I (Crohnbach's alpha = 0.84) and UMSARS-II (Crohnbach's alpha = 0.90) sections. The interrater reliability of most of the UMSARS-I and -II items as well as of total UMSARS-I and -II subscores was substantial (k (w) = 0.6-0.8) to excellent (k (w) > 0.8). UMSARS-II correlated well with UPDRS-III and ICARS (r<sub>s</sub>
> 0.8). Depending on the degree of the patient's disability, completion of the entire UMSARS took 30 to 45 minutes. Based on our findings, the UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients.</EA>
<CC>002B17; 002B17F; 002B17G</CC>
<FD>Système nerveux pathologie; Validation; Echelle d'évaluation; Atrophie multisystématisée</FD>
<ED>Nervous system diseases; Validation; Evaluation scale; Multiple system atrophy</ED>
<SD>Sistema nervioso patología; Validación; Escala evaluación; Atrofia multisistematizada</SD>
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