Movement Disorders (revue)

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Feasibility and validity of a modified finger-nose-finger test

Identifieur interne : 001E82 ( PascalFrancis/Corpus ); précédent : 001E81; suivant : 001E83

Feasibility and validity of a modified finger-nose-finger test

Auteurs : Elan D. Louis ; Lakeisha M. Applegate ; Sarah Borden ; Carol Moskowitz ; ZHEZHEN JIN

Source :

RBID : Pascal:05-0281447

Descripteurs français

English descriptors

Abstract

In essential tremor (ET) research, it is important to obtain standardized, objective data on tremor severity. Often, it is not possible to carry out in-person or videotaped neurological examinations. In place of these, handwriting samples can be collected, but they do not capture all of the variance in tremor severity. Although additional tests of tremor severity (finger-nose-finger [FNF] test) might be of use, these would need to be modified to allow ET patients to mail their results to the study investigator for rating. We modified the standard FNF test (sFNF) by asking subjects to hold a pen during this activity and mark a paper target. The purpose of this report was to determine whether the modified FNF (mFNF) test was feasible and valid. Of 70 subjects, 65 (92.9%) were able to complete the mFNF, demonstrating that it was feasible. The scores of the mFNF correlated highly with those of the sFNF (r = 0.56-0.85; all P < 0.001), indicating the mFNF is a valid measure of tremor severity. In addition, using the regression equation. sFNF = 0.174(mFNF) + 0.743, a sFNF score can be derived easily from the mFNF score. The mFNF may be used to collect valuable data on tremor severity in pathological, genetic, and epidemiological field studies of ET, in which in-person or videotaped neurological examinations are not possible.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A06       @2 5
A08 01  1  ENG  @1 Feasibility and validity of a modified finger-nose-finger test
A11 01  1    @1 LOUIS (Elan D.)
A11 02  1    @1 APPLEGATE (Lakeisha M.)
A11 03  1    @1 BORDEN (Sarah)
A11 04  1    @1 MOSKOWITZ (Carol)
A11 05  1    @1 ZHEZHEN JIN
A14 01      @1 G.H. Sergievsky Center, College of Physicians and Surgeons, Columbia University @2 New York, New York @3 USA @Z 1 aut. @Z 2 aut. @Z 3 aut.
A14 02      @1 Department of Neurology, College of Physicians and Surgeons, Columbia University @2 New York, New York @3 USA @Z 1 aut. @Z 4 aut.
A14 03      @1 Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians, and Surgeons, Columbia University @2 New York, New York @3 USA @Z 1 aut.
A14 04      @1 Department of Bioslatistics, Mailman School of Public Health, Columbia University @2 New York, New York @3 USA @Z 5 aut.
A20       @1 636-639
A21       @1 2005
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000124690200200
A44       @0 0000 @1 © 2005 INIST-CNRS. All rights reserved.
A45       @0 9 ref.
A47 01  1    @0 05-0281447
A60       @1 P
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A64 01  1    @0 Movement disorders
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C01 01    ENG  @0 In essential tremor (ET) research, it is important to obtain standardized, objective data on tremor severity. Often, it is not possible to carry out in-person or videotaped neurological examinations. In place of these, handwriting samples can be collected, but they do not capture all of the variance in tremor severity. Although additional tests of tremor severity (finger-nose-finger [FNF] test) might be of use, these would need to be modified to allow ET patients to mail their results to the study investigator for rating. We modified the standard FNF test (sFNF) by asking subjects to hold a pen during this activity and mark a paper target. The purpose of this report was to determine whether the modified FNF (mFNF) test was feasible and valid. Of 70 subjects, 65 (92.9%) were able to complete the mFNF, demonstrating that it was feasible. The scores of the mFNF correlated highly with those of the sFNF (r = 0.56-0.85; all P < 0.001), indicating the mFNF is a valid measure of tremor severity. In addition, using the regression equation. sFNF = 0.174(mFNF) + 0.743, a sFNF score can be derived easily from the mFNF score. The mFNF may be used to collect valuable data on tremor severity in pathological, genetic, and epidemiological field studies of ET, in which in-person or videotaped neurological examinations are not possible.
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C07 01  X  SPA  @0 Movimiento involuntario @5 37
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Format Inist (serveur)

NO : PASCAL 05-0281447 INIST
ET : Feasibility and validity of a modified finger-nose-finger test
AU : LOUIS (Elan D.); APPLEGATE (Lakeisha M.); BORDEN (Sarah); MOSKOWITZ (Carol); ZHEZHEN JIN
AF : G.H. Sergievsky Center, College of Physicians and Surgeons, Columbia University/New York, New York/Etats-Unis (1 aut., 2 aut., 3 aut.); Department of Neurology, College of Physicians and Surgeons, Columbia University/New York, New York/Etats-Unis (1 aut., 4 aut.); Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians, and Surgeons, Columbia University/New York, New York/Etats-Unis (1 aut.); Department of Bioslatistics, Mailman School of Public Health, Columbia University/New York, New York/Etats-Unis (5 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2005; Vol. 20; No. 5; Pp. 636-639; Bibl. 9 ref.
LA : Anglais
EA : In essential tremor (ET) research, it is important to obtain standardized, objective data on tremor severity. Often, it is not possible to carry out in-person or videotaped neurological examinations. In place of these, handwriting samples can be collected, but they do not capture all of the variance in tremor severity. Although additional tests of tremor severity (finger-nose-finger [FNF] test) might be of use, these would need to be modified to allow ET patients to mail their results to the study investigator for rating. We modified the standard FNF test (sFNF) by asking subjects to hold a pen during this activity and mark a paper target. The purpose of this report was to determine whether the modified FNF (mFNF) test was feasible and valid. Of 70 subjects, 65 (92.9%) were able to complete the mFNF, demonstrating that it was feasible. The scores of the mFNF correlated highly with those of the sFNF (r = 0.56-0.85; all P < 0.001), indicating the mFNF is a valid measure of tremor severity. In addition, using the regression equation. sFNF = 0.174(mFNF) + 0.743, a sFNF score can be derived easily from the mFNF score. The mFNF may be used to collect valuable data on tremor severity in pathological, genetic, and epidemiological field studies of ET, in which in-person or videotaped neurological examinations are not possible.
CC : 002B17; 002B24K; 002B17A07
FD : Système nerveux pathologie; Tremblement; Faisabilité; Validité; Doigt; Nez; Epidémiologie; Encéphale; Dépistage
FG : Mouvement involontaire; Trouble neurologique; Système nerveux central
ED : Nervous system diseases; Tremor; Feasibility; Validity; Finger; Nose; Epidemiology; Encephalon; Medical screening
EG : Involuntary movement; Neurological disorder; Central nervous system
SD : Sistema nervioso patología; Temblor; Practicabilidad; Validez; Dedo; Nariz; Epidemiología; Encéfalo; Descubrimiento
LO : INIST-20953.354000124690200200
ID : 05-0281447

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Pascal:05-0281447

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<div type="abstract" xml:lang="en">In essential tremor (ET) research, it is important to obtain standardized, objective data on tremor severity. Often, it is not possible to carry out in-person or videotaped neurological examinations. In place of these, handwriting samples can be collected, but they do not capture all of the variance in tremor severity. Although additional tests of tremor severity (finger-nose-finger [FNF] test) might be of use, these would need to be modified to allow ET patients to mail their results to the study investigator for rating. We modified the standard FNF test (sFNF) by asking subjects to hold a pen during this activity and mark a paper target. The purpose of this report was to determine whether the modified FNF (mFNF) test was feasible and valid. Of 70 subjects, 65 (92.9%) were able to complete the mFNF, demonstrating that it was feasible. The scores of the mFNF correlated highly with those of the sFNF (r = 0.56-0.85; all P < 0.001), indicating the mFNF is a valid measure of tremor severity. In addition, using the regression equation. sFNF = 0.174(mFNF) + 0.743, a sFNF score can be derived easily from the mFNF score. The mFNF may be used to collect valuable data on tremor severity in pathological, genetic, and epidemiological field studies of ET, in which in-person or videotaped neurological examinations are not possible.</div>
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<fC03 i1="01" i2="X" l="SPA">
<s0>Sistema nervioso patología</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Tremblement</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Tremor</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Temblor</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Faisabilité</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Feasibility</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Practicabilidad</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Validité</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Validity</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Validez</s0>
<s5>10</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Doigt</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Finger</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Dedo</s0>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Nez</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Nose</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Nariz</s0>
<s5>12</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Epidémiologie</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Epidemiology</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Epidemiología</s0>
<s5>13</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Encéphale</s0>
<s5>14</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Encephalon</s0>
<s5>14</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Encéfalo</s0>
<s5>14</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Dépistage</s0>
<s5>15</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Medical screening</s0>
<s5>15</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Descubrimiento</s0>
<s5>15</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Mouvement involontaire</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Involuntary movement</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Movimiento involuntario</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Trouble neurologique</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Système nerveux central</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Central nervous system</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Sistema nervioso central</s0>
<s5>39</s5>
</fC07>
<fN21>
<s1>199</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 05-0281447 INIST</NO>
<ET>Feasibility and validity of a modified finger-nose-finger test</ET>
<AU>LOUIS (Elan D.); APPLEGATE (Lakeisha M.); BORDEN (Sarah); MOSKOWITZ (Carol); ZHEZHEN JIN</AU>
<AF>G.H. Sergievsky Center, College of Physicians and Surgeons, Columbia University/New York, New York/Etats-Unis (1 aut., 2 aut., 3 aut.); Department of Neurology, College of Physicians and Surgeons, Columbia University/New York, New York/Etats-Unis (1 aut., 4 aut.); Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians, and Surgeons, Columbia University/New York, New York/Etats-Unis (1 aut.); Department of Bioslatistics, Mailman School of Public Health, Columbia University/New York, New York/Etats-Unis (5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2005; Vol. 20; No. 5; Pp. 636-639; Bibl. 9 ref.</SO>
<LA>Anglais</LA>
<EA>In essential tremor (ET) research, it is important to obtain standardized, objective data on tremor severity. Often, it is not possible to carry out in-person or videotaped neurological examinations. In place of these, handwriting samples can be collected, but they do not capture all of the variance in tremor severity. Although additional tests of tremor severity (finger-nose-finger [FNF] test) might be of use, these would need to be modified to allow ET patients to mail their results to the study investigator for rating. We modified the standard FNF test (sFNF) by asking subjects to hold a pen during this activity and mark a paper target. The purpose of this report was to determine whether the modified FNF (mFNF) test was feasible and valid. Of 70 subjects, 65 (92.9%) were able to complete the mFNF, demonstrating that it was feasible. The scores of the mFNF correlated highly with those of the sFNF (r = 0.56-0.85; all P < 0.001), indicating the mFNF is a valid measure of tremor severity. In addition, using the regression equation. sFNF = 0.174(mFNF) + 0.743, a sFNF score can be derived easily from the mFNF score. The mFNF may be used to collect valuable data on tremor severity in pathological, genetic, and epidemiological field studies of ET, in which in-person or videotaped neurological examinations are not possible.</EA>
<CC>002B17; 002B24K; 002B17A07</CC>
<FD>Système nerveux pathologie; Tremblement; Faisabilité; Validité; Doigt; Nez; Epidémiologie; Encéphale; Dépistage</FD>
<FG>Mouvement involontaire; Trouble neurologique; Système nerveux central</FG>
<ED>Nervous system diseases; Tremor; Feasibility; Validity; Finger; Nose; Epidemiology; Encephalon; Medical screening</ED>
<EG>Involuntary movement; Neurological disorder; Central nervous system</EG>
<SD>Sistema nervioso patología; Temblor; Practicabilidad; Validez; Dedo; Nariz; Epidemiología; Encéfalo; Descubrimiento</SD>
<LO>INIST-20953.354000124690200200</LO>
<ID>05-0281447</ID>
</server>
</inist>
</record>

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