Movement Disorders (revue)

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Medicine-taking behavior : Implications of suboptimal compliance in Parkinson's disease

Identifieur interne : 001D17 ( PascalFrancis/Corpus ); précédent : 001D16; suivant : 001D18

Medicine-taking behavior : Implications of suboptimal compliance in Parkinson's disease

Auteurs : Katherine A. Grosset ; John L. Reid ; Donald G. Grosset

Source :

RBID : Pascal:06-0077729

Descripteurs français

English descriptors

Abstract

Management of Parkinson's disease (PD) depends primarily on oral medication. There are several drug classes and multiple doses and formulations, which make optimizing therapy complex. Variable drug absorption and the short half-life of most antiparkinson treatments, especially levodopa, are a main focus in understanding complications and have encouraged alternative delivery systems to limit fluctuation and dyskinesia at later stages. Comparatively little attention is paid to the way patients take their oral medication. Variable medicine-taking behavior can affect the clinician's understanding of the diagnosis and rate of progression, and further prescription of PD medication. Medicine overuse in later stage PD is well documented and causes psychiatric disturbance and increases motor complications, but evidence of undertreatment and erratic intake is emerging, which is likely to affect motor control and quality of life adversely. Methods of quantifying compliance are compared for accuracy and limitations. Understanding medicine-taking behavior is a first step in optimizing therapy and requires consideration of a patient's personal beliefs about their medicines. Although the benefits of regularizing oral medicine-taking in a practical, achievable way in PD remain untested, such an approach might prolong and smooth the benefits of oral medication and is worthy of further research.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A08 01  1  ENG  @1 Medicine-taking behavior : Implications of suboptimal compliance in Parkinson's disease
A11 01  1    @1 GROSSET (Katherine A.)
A11 02  1    @1 REID (John L.)
A11 03  1    @1 GROSSET (Donald G.)
A14 01      @1 Institute of Neurological Sciences, Southern General Hospital @2 Glasgow @3 GBR @Z 1 aut. @Z 3 aut.
A14 02      @1 University Department of Medicine and Therapeutics, Western Infirmary @2 Glasgow @3 GBR @Z 2 aut.
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C01 01    ENG  @0 Management of Parkinson's disease (PD) depends primarily on oral medication. There are several drug classes and multiple doses and formulations, which make optimizing therapy complex. Variable drug absorption and the short half-life of most antiparkinson treatments, especially levodopa, are a main focus in understanding complications and have encouraged alternative delivery systems to limit fluctuation and dyskinesia at later stages. Comparatively little attention is paid to the way patients take their oral medication. Variable medicine-taking behavior can affect the clinician's understanding of the diagnosis and rate of progression, and further prescription of PD medication. Medicine overuse in later stage PD is well documented and causes psychiatric disturbance and increases motor complications, but evidence of undertreatment and erratic intake is emerging, which is likely to affect motor control and quality of life adversely. Methods of quantifying compliance are compared for accuracy and limitations. Understanding medicine-taking behavior is a first step in optimizing therapy and requires consideration of a patient's personal beliefs about their medicines. Although the benefits of regularizing oral medicine-taking in a practical, achievable way in PD remain untested, such an approach might prolong and smooth the benefits of oral medication and is worthy of further research.
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C03 02  X  FRE  @0 Parkinson maladie @5 02
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Format Inist (serveur)

NO : PASCAL 06-0077729 INIST
ET : Medicine-taking behavior : Implications of suboptimal compliance in Parkinson's disease
AU : GROSSET (Katherine A.); REID (John L.); GROSSET (Donald G.)
AF : Institute of Neurological Sciences, Southern General Hospital/Glasgow/Royaume-Uni (1 aut., 3 aut.); University Department of Medicine and Therapeutics, Western Infirmary/Glasgow/Royaume-Uni (2 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2005; Vol. 20; No. 11; Pp. 1397-1404; Bibl. 101 ref.
LA : Anglais
EA : Management of Parkinson's disease (PD) depends primarily on oral medication. There are several drug classes and multiple doses and formulations, which make optimizing therapy complex. Variable drug absorption and the short half-life of most antiparkinson treatments, especially levodopa, are a main focus in understanding complications and have encouraged alternative delivery systems to limit fluctuation and dyskinesia at later stages. Comparatively little attention is paid to the way patients take their oral medication. Variable medicine-taking behavior can affect the clinician's understanding of the diagnosis and rate of progression, and further prescription of PD medication. Medicine overuse in later stage PD is well documented and causes psychiatric disturbance and increases motor complications, but evidence of undertreatment and erratic intake is emerging, which is likely to affect motor control and quality of life adversely. Methods of quantifying compliance are compared for accuracy and limitations. Understanding medicine-taking behavior is a first step in optimizing therapy and requires consideration of a patient's personal beliefs about their medicines. Although the benefits of regularizing oral medicine-taking in a practical, achievable way in PD remain untested, such an approach might prolong and smooth the benefits of oral medication and is worthy of further research.
CC : 002B17; 002B17G; 002B17A03
FD : Système nerveux pathologie; Parkinson maladie; Comportement
FG : Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie
ED : Nervous system diseases; Parkinson disease; Behavior
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Sistema nervioso patología; Parkinson enfermedad; Conducta
LO : INIST-20953.354000134570810010
ID : 06-0077729

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Pascal:06-0077729

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