Action fluency in parkinson's disease : A follow-up study
Identifieur interne : 001B82 ( PascalFrancis/Corpus ); précédent : 001B81; suivant : 001B83Action fluency in parkinson's disease : A follow-up study
Auteurs : Matteo Signorini ; Chiara VolpatoSource :
- Movement disorders [ 0885-3185 ] ; 2006.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
The impairment in action fluency task present in Parkinson's disease (PD) patients has been previously interpreted as an indicator of conversion from PD to PD with dementia or as a grammatical deficit for verbs and ascribed to a frontostriatal loop pathophysiology. In the present study, 20 patients with PD without dementia were longitudinally tested with overall cognitive decline scales and semantic, letter, and action fluency tasks in a 24-month follow-up study. In comparison with healthy age-matched controls, PD patients showed a stable and consistent impairment on action fluency without any sign of cognitive decline. Our findings suggest that action fluency task may be an early sign of impairment of frontostriatal circuits in PD and it cannot be considered an indicator of conversion from PD to PD with dementia.
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Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 06-0244407 INIST |
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ET : | Action fluency in parkinson's disease : A follow-up study |
AU : | SIGNORINI (Matteo); VOLPATO (Chiara) |
AF : | Associuzione Fatebenefratelli per la Ricerca Biomedica e Sanitaria, San Ruffaele Arcangelo Hospital/Venice/Italie (1 aut., 2 aut.); Department of Science of Language, Ca' Foscari Venice University/Venice/Italie (1 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 4; Pp. 467-472; Bibl. 38 ref. |
LA : | Anglais |
EA : | The impairment in action fluency task present in Parkinson's disease (PD) patients has been previously interpreted as an indicator of conversion from PD to PD with dementia or as a grammatical deficit for verbs and ascribed to a frontostriatal loop pathophysiology. In the present study, 20 patients with PD without dementia were longitudinally tested with overall cognitive decline scales and semantic, letter, and action fluency tasks in a 24-month follow-up study. In comparison with healthy age-matched controls, PD patients showed a stable and consistent impairment on action fluency without any sign of cognitive decline. Our findings suggest that action fluency task may be an early sign of impairment of frontostriatal circuits in PD and it cannot be considered an indicator of conversion from PD to PD with dementia. |
CC : | 002B17; 002B17G; 002B17A03 |
FD : | Système nerveux pathologie; Parkinson maladie; Démence; Etude longitudinale |
FG : | Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie |
ED : | Nervous system diseases; Parkinson disease; Dementia; Follow up study |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease |
SD : | Sistema nervioso patología; Parkinson enfermedad; Demencia; Estudio longitudinal |
LO : | INIST-20953.354000156737350050 |
ID : | 06-0244407 |
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Pascal:06-0244407Le document en format XML
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<front><div type="abstract" xml:lang="en">The impairment in action fluency task present in Parkinson's disease (PD) patients has been previously interpreted as an indicator of conversion from PD to PD with dementia or as a grammatical deficit for verbs and ascribed to a frontostriatal loop pathophysiology. In the present study, 20 patients with PD without dementia were longitudinally tested with overall cognitive decline scales and semantic, letter, and action fluency tasks in a 24-month follow-up study. In comparison with healthy age-matched controls, PD patients showed a stable and consistent impairment on action fluency without any sign of cognitive decline. Our findings suggest that action fluency task may be an early sign of impairment of frontostriatal circuits in PD and it cannot be considered an indicator of conversion from PD to PD with dementia.</div>
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<AF>Associuzione Fatebenefratelli per la Ricerca Biomedica e Sanitaria, San Ruffaele Arcangelo Hospital/Venice/Italie (1 aut., 2 aut.); Department of Science of Language, Ca' Foscari Venice University/Venice/Italie (1 aut.)</AF>
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