Movement Disorders (revue)

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Sleep complaints and their relation with drug treatment in patients suffering from Parkinson's disease

Identifieur interne : 001A83 ( PascalFrancis/Corpus ); précédent : 001A82; suivant : 001A84

Sleep complaints and their relation with drug treatment in patients suffering from Parkinson's disease

Auteurs : Juan Carlos Gomez-Esteban ; Juan Jose Zarranz ; Elena Lezcano ; Fernando Velasco ; Roberto Ciordia ; Idoia Rouco ; Jose Losada ; Iker Bilbao

Source :

RBID : Pascal:06-0393861

Descripteurs français

English descriptors

Abstract

The aim of this research was to quantify sleep problems in patients suffering from Parkinson's disease by means of the new Parkinson's Disease Sleep Scale (PDSS) and to correlate such problems with the possible influence of current drug treatment. A total of 70 patients (36 men and 34 women) with a diagnosis of Parkinson's disease were enrolled. Their mean age was 69.7 ± 8.2 years, and duration of disease was 7.4 ± 4.8 years. All patients completed the PDSS and the Unified Parkinson's Disease Rating Scale (UPDRS Parts I-IV). Drug consumption and doses were registered. The mean score on the PDSS scale was 109.23 ± 19.75 and on the UPDRS III scale was 25.24 ± 11.35. The lowest scores were obtained in Item 3 (sleep fragmentation): 5.53 (2.46); and in Item 8 (nocturia): 5.75 (2.91). There was a weak correlation between the PDSS and UPDRS III (cc = -0.355, P = 0.003), PDSS and UPDRS I (cc = -0.272, P = 0.02), and PDSS and UPDRS IV (cc = -0.416, P < 0.001). Motor conditions, mental state, and drug complications influence sleep quality. Although this effect was significant, it was not of a great magnitude. Dopaminergic drugs did not increase daytime sleepiness. As a whole, sleep quality in patients who took dopaminergic agonists did not differ from that of patients who took levodopa in monotherapy.

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Pour connaître la documentation sur le format Inist Standard.

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A03   1    @0 Mov. disord.
A05       @2 21
A06       @2 7
A08 01  1  ENG  @1 Sleep complaints and their relation with drug treatment in patients suffering from Parkinson's disease
A11 01  1    @1 GOMEZ-ESTEBAN (Juan Carlos)
A11 02  1    @1 ZARRANZ (Juan Jose)
A11 03  1    @1 LEZCANO (Elena)
A11 04  1    @1 VELASCO (Fernando)
A11 05  1    @1 CIORDIA (Roberto)
A11 06  1    @1 ROUCO (Idoia)
A11 07  1    @1 LOSADA (Jose)
A11 08  1    @1 BILBAO (Iker)
A14 01      @1 Neurology Service, Movement Disorders Unit, Cruces Hospital @2 Baracaldo @3 ESP
A14 02      @1 Neurosciences Department, University of the Basque Country @2 Vizcaya @3 ESP
A20       @1 983-988
A21       @1 2006
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000133412770160
A44       @0 0000 @1 © 2006 INIST-CNRS. All rights reserved.
A45       @0 26 ref.
A47 01  1    @0 06-0393861
A60       @1 P
A61       @0 A
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C01 01    ENG  @0 The aim of this research was to quantify sleep problems in patients suffering from Parkinson's disease by means of the new Parkinson's Disease Sleep Scale (PDSS) and to correlate such problems with the possible influence of current drug treatment. A total of 70 patients (36 men and 34 women) with a diagnosis of Parkinson's disease were enrolled. Their mean age was 69.7 ± 8.2 years, and duration of disease was 7.4 ± 4.8 years. All patients completed the PDSS and the Unified Parkinson's Disease Rating Scale (UPDRS Parts I-IV). Drug consumption and doses were registered. The mean score on the PDSS scale was 109.23 ± 19.75 and on the UPDRS III scale was 25.24 ± 11.35. The lowest scores were obtained in Item 3 (sleep fragmentation): 5.53 (2.46); and in Item 8 (nocturia): 5.75 (2.91). There was a weak correlation between the PDSS and UPDRS III (cc = -0.355, P = 0.003), PDSS and UPDRS I (cc = -0.272, P = 0.02), and PDSS and UPDRS IV (cc = -0.416, P < 0.001). Motor conditions, mental state, and drug complications influence sleep quality. Although this effect was significant, it was not of a great magnitude. Dopaminergic drugs did not increase daytime sleepiness. As a whole, sleep quality in patients who took dopaminergic agonists did not differ from that of patients who took levodopa in monotherapy.
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C07 01  X  FRE  @0 Cycle veille sommeil @5 37
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C07 03  X  ENG  @0 Extrapyramidal syndrome @5 39
C07 03  X  SPA  @0 Extrapiramidal síndrome @5 39
C07 04  X  FRE  @0 Maladie dégénérative @5 40
C07 04  X  ENG  @0 Degenerative disease @5 40
C07 04  X  SPA  @0 Enfermedad degenerativa @5 40
C07 05  X  FRE  @0 Système nerveux central pathologie @5 41
C07 05  X  ENG  @0 Central nervous system disease @5 41
C07 05  X  SPA  @0 Sistema nervosio central patología @5 41
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Format Inist (serveur)

NO : PASCAL 06-0393861 INIST
ET : Sleep complaints and their relation with drug treatment in patients suffering from Parkinson's disease
AU : GOMEZ-ESTEBAN (Juan Carlos); ZARRANZ (Juan Jose); LEZCANO (Elena); VELASCO (Fernando); CIORDIA (Roberto); ROUCO (Idoia); LOSADA (Jose); BILBAO (Iker)
AF : Neurology Service, Movement Disorders Unit, Cruces Hospital/Baracaldo/Espagne; Neurosciences Department, University of the Basque Country/Vizcaya/Espagne
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 7; Pp. 983-988; Bibl. 26 ref.
LA : Anglais
EA : The aim of this research was to quantify sleep problems in patients suffering from Parkinson's disease by means of the new Parkinson's Disease Sleep Scale (PDSS) and to correlate such problems with the possible influence of current drug treatment. A total of 70 patients (36 men and 34 women) with a diagnosis of Parkinson's disease were enrolled. Their mean age was 69.7 ± 8.2 years, and duration of disease was 7.4 ± 4.8 years. All patients completed the PDSS and the Unified Parkinson's Disease Rating Scale (UPDRS Parts I-IV). Drug consumption and doses were registered. The mean score on the PDSS scale was 109.23 ± 19.75 and on the UPDRS III scale was 25.24 ± 11.35. The lowest scores were obtained in Item 3 (sleep fragmentation): 5.53 (2.46); and in Item 8 (nocturia): 5.75 (2.91). There was a weak correlation between the PDSS and UPDRS III (cc = -0.355, P = 0.003), PDSS and UPDRS I (cc = -0.272, P = 0.02), and PDSS and UPDRS IV (cc = -0.416, P < 0.001). Motor conditions, mental state, and drug complications influence sleep quality. Although this effect was significant, it was not of a great magnitude. Dopaminergic drugs did not increase daytime sleepiness. As a whole, sleep quality in patients who took dopaminergic agonists did not differ from that of patients who took levodopa in monotherapy.
CC : 002B17; 002B17G; 002B17F
FD : Système nerveux pathologie; Parkinson maladie; Trouble sommeil; Sommeil; Traitement; Homme; Lévodopa
FG : Cycle veille sommeil; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Trouble neurologique
ED : Nervous system diseases; Parkinson disease; Sleep disorder; Sleep; Treatment; Human; Levodopa
EG : Sleep wake cycle; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Neurological disorder
SD : Sistema nervioso patología; Parkinson enfermedad; Trastorno sueño; Sueño; Tratamiento; Hombre; Levodopa
LO : INIST-20953.354000133412770160
ID : 06-0393861

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Pascal:06-0393861

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</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Levodopa</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>12</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Cycle veille sommeil</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Sleep wake cycle</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Ciclo sueño vigilia</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Encéphale pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Extrapyramidal syndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Système nerveux central pathologie</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Trouble neurologique</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>42</s5>
</fC07>
<fN21>
<s1>261</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 06-0393861 INIST</NO>
<ET>Sleep complaints and their relation with drug treatment in patients suffering from Parkinson's disease</ET>
<AU>GOMEZ-ESTEBAN (Juan Carlos); ZARRANZ (Juan Jose); LEZCANO (Elena); VELASCO (Fernando); CIORDIA (Roberto); ROUCO (Idoia); LOSADA (Jose); BILBAO (Iker)</AU>
<AF>Neurology Service, Movement Disorders Unit, Cruces Hospital/Baracaldo/Espagne; Neurosciences Department, University of the Basque Country/Vizcaya/Espagne</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 7; Pp. 983-988; Bibl. 26 ref.</SO>
<LA>Anglais</LA>
<EA>The aim of this research was to quantify sleep problems in patients suffering from Parkinson's disease by means of the new Parkinson's Disease Sleep Scale (PDSS) and to correlate such problems with the possible influence of current drug treatment. A total of 70 patients (36 men and 34 women) with a diagnosis of Parkinson's disease were enrolled. Their mean age was 69.7 ± 8.2 years, and duration of disease was 7.4 ± 4.8 years. All patients completed the PDSS and the Unified Parkinson's Disease Rating Scale (UPDRS Parts I-IV). Drug consumption and doses were registered. The mean score on the PDSS scale was 109.23 ± 19.75 and on the UPDRS III scale was 25.24 ± 11.35. The lowest scores were obtained in Item 3 (sleep fragmentation): 5.53 (2.46); and in Item 8 (nocturia): 5.75 (2.91). There was a weak correlation between the PDSS and UPDRS III (cc = -0.355, P = 0.003), PDSS and UPDRS I (cc = -0.272, P = 0.02), and PDSS and UPDRS IV (cc = -0.416, P < 0.001). Motor conditions, mental state, and drug complications influence sleep quality. Although this effect was significant, it was not of a great magnitude. Dopaminergic drugs did not increase daytime sleepiness. As a whole, sleep quality in patients who took dopaminergic agonists did not differ from that of patients who took levodopa in monotherapy.</EA>
<CC>002B17; 002B17G; 002B17F</CC>
<FD>Système nerveux pathologie; Parkinson maladie; Trouble sommeil; Sommeil; Traitement; Homme; Lévodopa</FD>
<FG>Cycle veille sommeil; Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Trouble neurologique</FG>
<ED>Nervous system diseases; Parkinson disease; Sleep disorder; Sleep; Treatment; Human; Levodopa</ED>
<EG>Sleep wake cycle; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Neurological disorder</EG>
<SD>Sistema nervioso patología; Parkinson enfermedad; Trastorno sueño; Sueño; Tratamiento; Hombre; Levodopa</SD>
<LO>INIST-20953.354000133412770160</LO>
<ID>06-0393861</ID>
</server>
</inist>
</record>

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